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60181
TMF Attenuates Cognitive Impairment and Neuroinflammation by Inhibiting the MAPK/NF-κB Pathway in Alzheimer’s Disease: A Multi-Omics Analysis
Published 2025-02-01“…Among flavonoids, 3′,4′,5,7-tetramethoxyflavone (TMF), a structural analog of luteolin, has gained attention for its favorable pharmacokinetics and potential neuroprotective properties. …”
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60182
Photoelectrochemical characterization and photocatalytic properties of mesoporous TiO2/ZrO2 films
Published 2006-01-01“…Optically transparent, crack-free mesoporous titania and zirconia-doped titania thin film photocatalysts were fabricated by sol-gel technique, using nonionic amphiphilic block copolymer Pluronic P123 as template. The structural and optical properties of these films were characterized using SEM, low-angle XRD, and UV/Vis spectroscopy, hexane adsorption investigation. …”
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60183
Comprehensive in vivo and in vitro metabolic profiling of amphenmulin: a novel pleuromutilin derivative characterized by UHPLC-Q-TOF-MS/MS
Published 2025-08-01“…These findings provide a structural basis for further investigation into the pharmacokinetics and safety profile of amphenmulin and serve as a reference for the development and optimization of other pleuromutilin derivatives.…”
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60184
Application of decellularization methods for scaffold production: advantages, disadvantages, biosafety and modifications
Published 2025-06-01“…Scaffolds derived from animal sources offer promising structural and biochemical properties but require thorough decellularization to minimize immunogenicity and maintain extracellular matrix integrity. …”
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60185
Enhancing the Catalytic Kinetics of Electrodes by using a Multidimensional Carbon Network for Applications in Vanadium Redox Flow Batteries
Published 2020-02-01“…Based on the above‐mentioned structural design, a battery containing the composite electrodes exhibited excellent cycling stability without any obvious efficiency decay after 1000 cycles, indicating its applicability for large‐scale VRFBs.…”
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60186
Expression and Localization of hspa5 in Response to Thermal Stress in the Spotted Sea Bass (Lateolabrax maculatus)
Published 2025-08-01“…Structural modeling indicated that the secondary structure of HSPA5 was predominantly composed of α-helices, accompanied by some irregular coiling.To investigate the response mechanism of hspa5 in L. maculatus under high-temperature stress, we analyzed its expression in liver tissue using real-time quantitative polymerase chain reaction (qPCR) under a 30 ℃ heat stress condition. …”
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60187
SCREEN ATTRACTIONS: BETWEEN VISUAL AND NARRATIVE / АТТРАКЦИОНЫ ЭКРАНА: МЕЖДУ ВИЗУАЛЬНЫМ И НАРРАТИВНЫМ
Published 2021-03-01“…Based on a number of provisions of aesthetics and film semiotics, the article interprets the structural features of the attractions of screen civilization and analyzes their varieties in the context of serial art products that reveal their structural and receptive specifics. …”
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60188
Modeling collective behavior in groups of mice housed under semi-naturalistic conditions
Published 2025-04-01“…Applying maximum entropy models on the coarse-grained co-localization patterns of mice unveils social rules in mouse hordes, quantifying sociability through pairwise interactions within groups, the impact of individual versus social preferences, and the effects of considering interaction structures among three animals instead of two. Reproducing co-localization patterns of individual mice reveals stability over time, with the statistics of the inferred interaction strength capturing social structure. …”
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60189
The hierarchical folding dynamics of topologically associating domains during early embryo development
Published 2025-07-01“…Abstract Background Recent research has indicated a close connection between the three-dimensional (3D) structure of chromatin and early embryo development, with precise higher-order chromatin folding playing a significant role in mediating gene expression. …”
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60190
The Impact of Age and Sex on Left Ventricular Function Based on Transthoracic Echocardiograms
Published 2025-06-01“…Background: This study aimed to reveal the age- and gender-related differences in left ventricular function among patients with normal cardiac structure. …”
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60191
Decoding Mycoplasma Nucleases: Biological Functions and Pathogenesis
Published 2025-04-01“…Certain nucleases, either membrane-bound or secreted, not only contribute to the growth of mycoplasmas but also serve as key virulence factors due to their unique spatial structures and physiological activity. The pathogenesis includes, but is not limited to, degradation of host DNA and RNA, leading to disruptions of nucleic acid metabolism and the induction of host cell apoptosis; degradation of neutrophil extracellular traps (NETs), allowing escape from neutrophil-mediated killing; and upregulation of inflammatory molecules to modulate the immune response of the host. …”
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60192
Sequential multiple assignment randomised trial to develop an adaptive mobile health intervention to increase physical activity in people poststroke in the community setting in Ire...
Published 2024-01-01“…To this end, we aim to use a Sequential Multiple Assignment Randomised Trial (SMART) design to develop an adaptive, user-informed mHealth intervention to improve PA poststroke.Methods and analysis The components included in the 12-week intervention are based on empirical evidence and behavioural change theory and will include treatments to increase participation in Structured Exercise and Lifestyle or a combination of both. 117 participants will be randomly assigned to one of the two treatment components. …”
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60193
Linking Digital Footprint Data into Longitudinal Population Studies
Published 2025-06-01“…Methods We propose a structured, four-stage framework to facilitate successful linkage of digital footprint data into LPS: (1) understand participant expectations and acceptability; (2) collect and link the data; (3) evaluate properties of the data; and (4) ensure secure and ethical access for research. …”
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60194
Perspectives of Physiotherapists on Immune Functioning in Oncological Rehabilitation in the Netherlands: Insights from a Qualitative Study
Published 2025-08-01“…For this qualitative research, semi-structured interviews were performed with Dutch oncology physiotherapists. …”
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60195
A dual-phase financial strategy for sustainable customer loyalty: Integrating fixed deposits and voucher systems in Sri Lankan supermarket retail
Published 2025-06-01“…The framework provides retail managers with a structured approach to capitalise on seasonal demand while building long-term customer relationships, particularly applicable to emerging markets where traditional loyalty programs may be insufficient. …”
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60196
School physical education and health based on the principles of body literacy: propositions and validation of an educational technology
Published 2025-07-01“…The developed ET comprises 17 pages, structured around three topics: School Physical Education as a promoter of health, the concept and principles of BL, and successful practical experiences. …”
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60197
Perceptions of a comprehensive telehealth intervention in patients with persistently poor type 2 diabetes control
Published 2025-01-01“…Methods: We conducted semi-structured interviews of a purposive sample of patients and staff in the comprehensive telehealth arm of the Practical Telehealth to Improve Control and Engagement for Patients with Clinic-Refractory Diabetes Mellitus study. …”
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60198
The path to teaching Excellence: Examining self-efficacy of pre-service teachers during school internship programs in Indonesia
Published 2025-01-01“…The study highlights the critical role of structured internships, mentorship, and reflective practices in enhancing PSTs' self-efficacy. …”
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60199
A qualitative exploration of service users' experiences of weight management conversations in a mental health setting
Published 2025-06-01“…Methods: Thirteen service users with serious mental illness (Nine inpatient, four community-based) participated in semi-structured 1–1 interviews exploring weight management support experiences. …”
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60200
Digital Platform Empowering China-Pakistan Economic Corridor Disaster Management: Enhancing Data Integration, Resilience, and Policy Innovation
Published 2025-06-01“…To ensure data integrity and security, four disaster management standards and a structured data integration framework were established, consolidating resources from seven thematic data corridors spanning natural hazard, ecological environment, and socioeconomic fields. …”
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