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59621
Exploring the role of toxic and therapeutic compounds in aryl hydrocarbon receptor (AhR) modulation: insights from molecular modeling study
Published 2025-06-01“…Yet, studying AhR’s role in toxicology, physiology, and disease is challenging due to limited structural data. To overcome this, computational molecular modeling techniques like molecular docking, molecular dynamics (MD) simulations, and homology modeling have become crucial tools in AhR research. …”
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59622
COMPARATIVE MORPHOFUNCTIONAL CHARACTERISTIC OF ADRENAL GLANDS IN ARTERIAL HYPERTENSION
Published 2015-10-01“…In each case, each of the adrenal glands were assessed: the presence and severity of focal and diffuse mononuclear infiltration, the number of lympho-cytes, monocytes, plasma cells and fibroblasts arranged in the respective zones of the cortex and medulla, the severity of hyperemia and edema of various structural parts, the number of zones cortex and medulla endocrinocytes with pycnotic nuclei in the reticular zone evaluated the distribution of secretory cells with lipofuscin and the degree of saturation of the cytoplasm of the secretory cells, in secretory cells of medul-la evaluated nuclear-cytoplasmic ratio, the severity of vacuolization and basophils cytoplasm revealed a number of regularities of morphological changes depending from the various clinical manifestations of hypertension, defining the ultimate option of dying. …”
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59623
Receipt of humanitarian cash transfers, household food insecurity and the subjective wellbeing of Syrian refugee youth in Jordan
Published 2025-01-01“…We employ stepwise model building and structural equation models. Setting: Jordan. Participants: Syrian refugee youth aged 16–30 (n 1572). …”
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59624
Protective bioactivity of Ziziphus jujuba dates polysaccharide on colitis via improving the intestinal barrier and modifying the gut microbiota
Published 2025-09-01“…Moreover, ZJP-I was found to increase the quantity of goblet cells and crypts, which in turn promoted the structural integrity of the colon. Additionally, it could partially restore the length of the colon and enhance the expression of tight junction proteins. …”
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59625
Investigating the role of environmental pollution in urban health and ways to reduce it (Case study: Karaj city)
Published 2025-03-01“…Using a simple random sampling method and the Cochran formula, a total of 400 participants were selected. Structural equation modeling was employed to analyze the data with SPSS software. …”
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59626
Tomato Pomace as a Valuable Resource: Characterization of Sunflower and Rapeseed Oil Extracts from Ox Heart Tomato (<i>Lycopersicon esculentum</i>)
Published 2025-05-01“…Fourier-transform infrared spectroscopy (FTIR) identified key functional groups and structural modifications, while differential scanning calorimetry (DSC) revealed differences in thermal stability across the samples. …”
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59627
SYNTHESIS OF A MULTI-MODE INTELLECTUAL SYSTEM OF MANAGEMENT OF A WEAKLY FORMED PROCESS
Published 2022-08-01“…The main ones are the difficulty of obtaining a mathematical model due to the incompleteness of knowledge of kinetic laws, the presence of various types of noniinearities in the mathematical model, non-stationarity, as well as significant structural and parametric uncertainty that manifests itself in the process of functioning. …”
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59628
Smart Data-Enabled Conservation and Knowledge Generation for Architectural Heritage System
Published 2025-06-01“…Validated through dual case studies—the Historical Educational Sites in South China (humanistic narratives) and the Dong ethnic drum towers (structural logic)—the framework demonstrates its capacity to automate knowledge generation, converting 20.5 GB of multi-source data into 2652 RDF triples that interconnect 1701 nodes across HBIM models and archival records. …”
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59629
Digital Twin-Based Ecogreen Building Design
Published 2021-01-01“…In order to solve the problem of insufficient capability of green building operation cost management, based on the digital twin technology in the manufacturing field, we analyze the characteristic requirements and theoretical basis of green building operation cost management for system, propose a green building operation cost management system based on digital twin, and refine the design of each structural layer of this system. It is necessary to set up a series of lines, although it takes a certain amount of time. …”
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59630
Why do many educated individuals leave Zimbabwe? Economic realities and the draw of developed countries
Published 2024-06-01“…Targeted interventions to address structural issues and to promote a more inclusive economic environment in Zimbabwe are deemed necessary.…”
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59631
Social and psychological climate as a factor in professional training of students of technical universities
Published 2025-02-01“…In addition, the key elements that form a team as a stable system, including self-management mechanisms and structural interactions, have been identified. The practical significance of the research lies in the possibility of applying the data obtained for team management in higher education and teacher training. …”
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59632
The Autophagy Receptor TAX1BP1 and the Molecular Motor Myosin VI Are Required for Clearance of Salmonella Typhimurium by Autophagy.
Published 2015-10-01“…The absence of TAX1BP1 causes an accumulation of ubiquitin-positive Salmonella, whereas loss of myosin VI leads to an increase in ubiquitylated and LC3-positive bacteria. Our structural studies demonstrate that the ubiquitin-binding site of TAX1BP1 overlaps with the myosin VI binding site and point mutations in the TAX1BP1 zinc finger domains that affect ubiquitin binding also ablate binding to myosin VI. …”
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59633
User Experience Analysis of an Original Website Designed with Simplicity from the Perspective of Technology Acceptance Model
Published 2023-06-01“…Data were analyzed by Structural Equation Modeling (SEM), in the context of five hypotheses. …”
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59634
Preferences for Capturing Market Share of Halal Products in the 5.0 Era Through the UTAUT-3 Model for MSME in Lhokseumawe City
Published 2025-04-01“…Quantitative data were analyzed using the Partial Least Squares Structural Equation Modeling (PLS-SEM) method, while qualitative data were examined through triangulation and the Analytical Network Process (ANP) method. …”
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59635
How significantly are principal and teacher entrepreneurial leadership related to teacher efficacy and organizational effectiveness in China?
Published 2025-04-01“…A quantitative research design was employed, utilizing structural equation modeling (SEM). Data were collected through paper-based questionnaires administered to 400 teachers in Shandong Province, China. …”
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59636
Non-traditional plant raw materials in the production technology of flour confec-tionery products
Published 2024-10-01“…The purpose of the research is to theoretically substantiate the enrichment of flour confectionery products with non-traditional plant raw materials in order to improve the nutrient composition, organoleptic, structural and mechanical indicators, and increase shelf life. …”
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59637
Mediation and moderation analysis of the association between physical capability and quality of life among stroke patients.
Published 2025-01-01“…Patients' mental and physical function was assessed using the Brunnstrom recovery stage (BRS), mini-balance evaluation system test (Mini-BEST), Barthel index (BI), Activities-specific Balance Confidence scale (ABC), and Hamilton depression scale (HAM-D). The structural equation model (SEM) was used to test the moderated mediation model in Mplus 8.0 software. …”
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59638
Determination of neurometabolism in patients with mild and moderate cognitive impairments
Published 2016-02-01“…PET hypometabolism characterizes either structural organic abnormalities in the brain in the presence SCVA or initial manifestations of the neurodegenerative process. 3. …”
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59639
The Impact of Foreign Direct Investment on Economic Development in South Asia and Southeastern Asia
Published 2025-06-01“…These recommendations are grounded in empirical evidence and tailored to the region’s structural characteristics, offering actionable insights for policy-makers.…”
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59640
Effects of Temperature and Secondary Orientations on the Deformation Behavior of Single-Crystal Superalloys
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