Natural plant-derived nanovesicles for effective psoriasis therapy via dual modulation of IL-17 and NRF2 pathway by Sreeram Peringattu Kalarikkal, Meghana N. Kumar, Soundaram Rajendran, Cathrine M.S. Bethi, Jahnavi Ravilla, Janakiraman Narayanan, Gopinath M. Sundaram

“…Plant-derived exosome-like nanovesicles (PDNVs) are exosome-mimetic structures isolated from plants with enhanced bioavailability and solubility. …”
Get full text

PID-CD: PID Control is What Change Detection Needs by Zhiwei Ye, Shirui Sheng, Qiyi He, Mingwei Wang, Chuan Xu, Zhina Song, Ziqian Fang, Liye Mei, Lingyu Yan, Xudong Lai

“…The PIDFA enhances and corrects the change region features using manifold structures and adaptive strategies, while the PIDFF introduces a third branch to guide multilevel feature fusion, progressively refining the boundaries of the change regions. …”
Get full text

Synergistic activation of the human phosphate exporter XPR1 by KIDINS220 and inositol pyrophosphate by Peng Zuo, Weize Wang, Zonglin Dai, Jiye Zheng, Shang Yu, Guangxi Wang, Yue Yin, Ling Liang, Yuxin Yin

“…Here we report cryo-EM structures of the human XPR1-KIDINS220 complex in substrate-free closed and substrate-bound outward-open states, as well as an XPR1 mutant in a substrate-bound inward-facing state. …”
Get full text

Selective electrocatalytic nitrate reduction to dinitrogen: Mechanisms, catalysts, and challenges by Jiayu Chen, Anni Wu, Yongfeng Xie, Yumin Zhang, Hu Zheng, Wei Teng

“…Various classes of electrocatalysts, including monometallic, bimetallic, and single-atom systems, oxide-based and carbon-based materials, examining how their structures regulate key intermediates and NN coupling. …”
Get full text

Prevalence and determinants of abortion among married women of reproductive age in rural and urban areas of the Southeastern Zone of Tigray, Ethiopia, 2024 a postwar study by Abrehaley Teklemariam Gebremariam, Girmatsion Fisseha Abreha, Kinfe Abraha Gebre-Egziabher, Awtachew Berhe Weldu

“…Data were collected through structured questionnaires. Quantitative data were analyzed using STATA version 17, employing descriptive statistics and logistic regression to identify factors associated with abortion. …”
Get full text

What do we know about nursing practice in relation to functional ability limitations, frailty and models of care among older people in home- and facility-based care: a scoping revi... by Ida Røed Flyum, Edith Roth Gjevjon, Anna Josse Eklund, Gunilla Borglin

“…Abstract Background Nursing practice in long-term care, must support the delivery of safe and evidence-based care, especially for older people with functional ability limitations and frailty, with the competency, knowledge and structured working modes such practice requires. Understanding, detecting and preventing these conditions is important in a context where care is given to a significant number of older people with complex care needs. …”
Get full text

A multi methods study to explore the impact of the COVID-19 pandemic on the psychological well-being of cancer nurses across Cheshire and Mersey by Lynda Appleton, Courtney Atkins, Sarah Watmough, Helen Poole

“…Methods A multi methods approach comprising a repeated measures survey (n = 69), semi-structured interviews (n = 29) and two focus groups was used. …”
Get full text

Compliance with Weekly Iron and Folic Acid Supplementation and Its Associated Factors among Adolescent Girls in Tamale Metropolis of Ghana by S. Dajaan Dubik, Kingsley E. Amegah, Amshawu Alhassan, Louis N. Mornah, Loveland Fiagbe

“…A cross-sectional study was conducted among 424 randomly sampled adolescent girls in the Tamale Metropolis of Ghana from April to July 2019 using an interviewer-administered structured questionnaire. Twenty school health coordinators were purposively selected to answer questions on the challenges they face in implementing the IFAS program at the school level. …”
Get full text

Fuzzy model-based analysis of user feedback for product development insights by Anna Sudár, Borbála Berki, Ildikó Horváth

“…The primary objective of this paper is to present a structured modeling framework, incorporating user feedback to support software product development. …”
Get full text

Point-of-caRE DiagnostICs for respiraTOry tRact infectionS (PREDICTORS) study: developing guidance for using C-reactive protein point-of-care tests in the management of lower respi... by Tom Fahey, Carmel Hughes, Akke Vellinga, Cristin Ryan, Gerard J Molloy, Cathal Cadogan, Joseph O’Shea

“…The panel emphasised the need for structured guidelines to align CRP POCT use with clinical context and highlighted its role in improving diagnostic confidence while supporting antibiotic stewardship.Conclusions This study provides a set of best practice guidance statements to support the use of CRP POCT in the management of LRTIs in primary care. …”
Get full text

Community health fairs as experiential learning: a qualitative exploration of benefits and challenges by Martha Rojo, Scott Wright, Jing Jin, Erickson Feliciano, Margaret Love, Sharon Stevenson

“…Methods Using a semi-structured guide developed by the researchers for this study, qualitative conversational interviews were conducted with 14 participants (7 students, 7 faculty) involved in an annual CHF. …”
Get full text

Developing and validating a machine learning-based model for predicting in-hospital mortality among ICU-admitted heart failure patients: A study utilizing the MIMIC-III database by De Su, Jie Zheng, Yue-kai Shao, Jun-ya Liu, Xin-xin Liu, Kun Yu, Bang-hai Feng, Hong Mei, Song Qin

“…Methods This study, based on the MIMIC-III database, extracted demographic characteristics, vital signs, laboratory test values, and comorbidity information of heart failure patients using structured query language. LASSO regression was employed for feature selection, and various machine learning algorithms were utilized to train models, including logistic regression (LR), random forest (RF), and gradient boosting (GB), among others. …”
Get full text

The relationship between cognitive disengagement syndrome and misophonia in children with attention deficit hyperactivity disorder: the mediating role of cognitive disengagement sy... by Hacer Gizem Gercek, Borte Gurbuz Ozgur, Zahittin Hayta, Asiye Sapanca, Hatice Aksu

“…All participants underwent a semi-structured clinical interview using the Kiddie Schedule for Affective Disorders and Schizophrenia for School-Age Children–Present and Lifetime Version, Turkish version (K-SADS-PL). …”
Get full text

Exploring the life experiences of school‐aged children afflicted by tethered spinal cord syndrome: An interpretative qualitative study by Nan Lin, Mingxian Ren, Yujun Xiang, Jiahuan Li, Dan Wang, Hongzhen Xu

“…The research design used an interpretative qualitative approach, utilising semi‐structured interviews as the primary data collection method. …”
Get full text

Evaluating modified early warning score compliance to minimise unnecessary ICU admissions: a needs assessment for quality improvement implementation by Amir Hassan, Malik W.Z. Khan

“…These measures can optimise ICU resource allocation and reduce unnecessary admissions, ensuring a structured, yet flexible triaging approach that balances protocol adherence with clinical discretion.…”
Get full text

Financial performance of hospitals in Europe – a scoping review by Katarzyna Dubas-Jakóbczyk, Costase Ndayishimiye, Przemysław Szetela, Christoph Sowada, Ewa Kocot

“…Although fragmented data indicate that hospitals in many European countries face financial problems, no structured, comparative data are available. The objective of this study was to identify, synthetize, and map the existing evidence on hospital financial performance (FP) across European countries. …”
Get full text

Uptake of early infant diagnosis (EID) at six weeks after cessation of breastfeeding among HIV exposed children: A cross sectional survey at six high volume health facilities in Ir... by Sophia Samson, Rose N. Mpembeni, Prosper F. Njau, Rogati S. Kishimba

“…Mothers and caregivers were interviewed using pretested structured questionnaires. Logistic regression analysis was used to assess factors influencing uptake of the test while controlling for potential confounders. …”
Get full text

The economic and social burden of pediatric cerebral palsy in Spain: a cost-of-illness study by Diana Marcela Nova-Díaz, Paloma Arana-Rivera, Eduardo Sánchez-Iriso, Sergio Aguilera-Albesa

“…Data collection included structured questionnaires and administrative records from regional healthcare and government sources, covering a 1-year period. …”
Get full text

Two lenses for exploring relationships between seabirds and fishers: Unveiling reciprocal contributions by Jaime Ojeda, Flavia Morello, Cristián G. Suazo, María S. Astorga‐España, Anne K. Salomon, Natalie C. Ban

“…From a human perspective, ethnographic methods (e.g., semi‐structured interviews) are analysed with Nature's Contributions to People and reciprocal contribution frameworks. …”
Get full text

Comparative efficacy of dietary interventions for glycemic control and pregnancy outcomes in gestational diabetes: a network meta-analysis of randomized controlled trials by Jiaoyang Di, Jingjing Fan, Fangxu Ma

“…The remaining trials compared standard dietary recommendations or structured meal planning. The DASH diet was the most effective intervention for glycemic control, significantly reducing FBG (SMD = -2.35, 95% CI [-4.15, -0.54]), 2h-PBG (SMD = -1.41, 95% CI [-2.56, -0.25]), and HOMA-IR (MD = -1.90, 95% CI [-2.44, -1.36]). …”
Get full text