New Alternatives for Autoimmune Disease Treatments: Physicochemical and Clinical Comparability of Biosimilar Etanercept by Mariana P. Miranda-Hernández, Carlos A. López-Morales, Francisco C. Perdomo-Abúndez, Rodolfo D. Salazar-Flores, Nancy D. Ramírez-Ibanez, Nestor O. Pérez, Aarón Molina-Pérez, Jorge Revilla-Beltri, Luis F. Flores-Ortiz, Emilio Medina-Rivero

“…Identity analyses showed a total correspondence of the primary and higher-order structure between the two products. In regard to intrinsic heterogeneity, both products showed to be highly heterogenous; however the biosimilar etanercept exhibited similar charge and glycan heterogeneity intervals compared to the reference product. …”
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Meat Products 3D Printing Technology and Application Progress by Shuailei XIAO, Yu JIANG, Qiang TONG

“…In recent years, 3D printing technology has been used in the food field to realize the advantages of complex food structure, personalized customization and reduce resource consumption. …”
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PREPARATION AND PHYSICAL PROPERTIES OF OPAL MATRICES WITH NANOPARTICLES OF TITANIUM AND IRON OXIDES by M. I. Samoylovich, А. F. Belyanin, A. S. Bagdasaryan

“…The composition and structure of the nanocomposites were studied by electron microscopy, X-ray diffraction and Raman spectroscopy. …”
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Clinical Efficacy and Safety of Ivacaftor/Lumacaftor Combination in Patients with Cystic Fibrosis: International Studies Review by Nataliya Yu. Kashirskaya, Nika V. Petrova, Rena A. Zinchenko

“…Cystic fibrosis is an autosomal recessive disease caused by structure abnormalities in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. …”
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Determining Passenger Profile According to Types of Transport in Konya: A Clustering Analysis by Nilüfer Canöz, Zeynep Ergen Işıklar, Ahmet Ertek

“…In this study, the travel preferences and demographic structure of travellers were associated with a cluster analysis through the types of transportation that exist in the province of Konya. …”
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A Cloud-Computing-Based Data Placement Strategy in High-Speed Railway by Hanning Wang, Weixiang Xu, Futian Wang, Chaolong Jia

“…In this paper, a new data placement strategy named hierarchical structure data placement strategy is proposed. The proposed method combines the semidefinite programming algorithm with the dynamic interval mapping algorithm. …”
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What’s the TEE: Metrics of Temperature Extremes in Europe NUTS Regions (1980-2024) by Sara R. Ronnkvist, Zoé Haskell-Craig, Abbie Robinson, Risto Conte Keivabu, Mathew E. Hauer, Domenico Bovienzo, Emilio Zagheni

“…Although publicly available, climate data format and spatial resolution rarely matches the structure, scale, and extent used to disseminate government statistics on health, economic, and demographic variables, and manipulating raw data is computationally expensive. …”
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Complex travelling wave solutions of fractional nonlinear coupled malaria model: bifurcation, chaos, and multistability by Abdullah, Muhammad Shakeel, Shah Muhammad, Hameed Gul Ahmadzai

“…These findings offer new understanding into the modeling of disease spread and provide a strong structure for future research in malaria control. Finally, the study contributes to the development of more accurate predictive models with potential applications in the biomedical sciences, extending the role of fractional calculus in comprehension complex biological systems.…”
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Network analysis of loneliness, mental, and physical health in Czech adolescents by Zdenek Meier, Jakub Helvich, Jana Furstova, Lukas Novak, Dana Purova, Radka Zidkova, Peter Tavel

“…The network analysis based on undirected graphical models was used as an exploratory technique to assess and test the structure of the data. Results The association between loneliness and health decreased with age. …”
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Chicken NLRP3 monoclonal antibody development and its antigenic epitope identification by Mengmeng Xu, Mengmeng Huang, Guodong Wang, Jingzhe Han, Hangbo Yu, Yulong Zhang, Runhang Liu, Ziwen Wu, Hongyu Cui, Yanping Zhang, Suyan Wang, Yongzhen Liu, Yuntong Chen, Yulu Duan, Liuan Li, Yulong Gao, Xiaole Qi

“…The developed mAb provides an important tool for detecting chicken NLRP3 and facilitates further study of its antigenic structure and biochemical characteristics.…”
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Ferroptosis inducers – erastin and analogues (review) by E. V. Sanarova, A. V. Lantsova, L. L. Nikolaeva, N. A. Oborotova, L. M. Borisova

“…Erastin is a unique molecule that has a quinazoline fragment in its structure. Not so long ago it became known that the antitumour effect of this compound is due to the induction of ferroptosis – an iron-dependent form of cell death caused by lipid peroxidation. …”
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Modeling and Analysis of Noise Reduction Method in SPAD-Based LiDAR System by Kai Ma, Tao Yin, Na Tian, Zhe Wang, Tian Zhao, Jian Liu, Nanjian Wu, Liyuan Liu

“…Multi-event mode and time-gating method are extensively employed due to their effective suppression ability of the ambient light interference with easily implemented circuit structure. However, the current research on these two operational modes is limited to qualitative description, lacking a comprehensive theoretical analysis. …”
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Recent advances in studying natural bioactive polysaccharides with in vitro gastrointestinal digestion models by Jing-Ya Zeng, Xu Yang, Jian-Hui Xiao, Yan Yang, Mi-shuai Zhang, Ru-Ming Liu

“…They are capable of accurately predicting the relationships between the composition, structure, and digestive characteristics of polysaccharides, while effectively assessing their impact on gastrointestinal health. …”
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Strain heterogeneity in RuO2 for efficient acidic oxygen evolution reaction in proton exchange membrane water electrolysis by Xuejie Cao, Licheng Miao, Wenqi Jia, Hongye Qin, Guangliang Lin, Rongpeng Ma, Ting Jin, Lifang Jiao

“…Experiments and calculations analyses confirm that the bulk tensile strain effectively stabilizes the entire structure of electrocatalysts, while the regions of compressive strain are identified as highly active catalytic sites, where the weakened binding energy of oxo-intermediates improves the catalytic activity.…”
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Synthesis and Pharmacological Valorization of Derivatives of 4-Phenyl-1,5-Benzodiazepin-2-One by Terence Nguema Ongone, Redouane Achour, Mostafa El Ghoul, Latifa El Ouasif, Khalid Taghzouti, Meryem El Jemli, Yahia Cherrah, Katim Alaoui, Amina Zellou

“…The objective of our work is to make a pharmacological study of molecules derived from 4-phenyl-1,5-benzodiazepin-2-one carrying long chains so that they have a structure similar to surfactants, with the benzodiazepine as a hydrophilic head and a carbon chain as a hydrophobic tail. …”
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Interaction between Brine and Wolfberry and Its Effect on the Quality of Wolfberry Betel Nut by LI Hao, MA Chen-wei, HUANG Qun, WANG Xiao-yu, CAO Jian-hua, SUN Min, FENG Tao

“…The results indicated that alkaline components in the areca nut brine disrupt the structure of wolfberry, promoting the conversion of bound water to free water and triggering the rehydration phenomenon. …”
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Disentangling the development of collective flow in high energy proton proton collisions with a multiphase transport model by Liang Zheng, Lian Liu, Zi-Wei Lin, Qi-Ye Shou, Zhong-Bao Yin

“…Abstract In this work, we investigate the collective flow development in high energy proton proton (pp) collisions with a multiphase transport model (AMPT) based on PYTHIA8 initial conditions with a sub-nucleon structure. It is found that the PYTHIA8 based AMPT model can reasonably describe both the charged hadron productions and elliptic flow experimental data measured in pp collisions at $$\sqrt{s}=13$$ s = 13 TeV. …”
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A COMPARISON OF DIFFERENT LIPOPOLYSACCHARIDE CHEMOTYPES FROM ESCHERICHIA COLI AND SALMONELLA UPON SYNTHESIS OF TNFα AND IL-6 BY MACROPHAGE-LIKE THP-1 CELLS by E. V. Voloshina, S. V. Zubova, S. V. Prokhorenko, N. I. Kosjakova, I. R. Prokhorenko

“…A contribution of lipid A structure into biological activity of LPS is more significant for Re-chemotype than for S-chemotype, independently on bacterial species.…”
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Influence of Seismic Source Parameters on the Excitation Wavelet in Seismic Explorations Based on Numerical Simulation by Ruohua Qiu, Zhaoxing Dong, Yanjun Qi, Yanhui Wang, Lidong Xie, Honghua Liu

“…The optimum charge weight is 16–18 kg, and the ideal charging structure is in a concentrated, short-column shape. …”
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Drug repurposing reveals posaconazole as a CYP11A1 inhibitor enhancing anti-tumor immunity by Jhuma Pramanik, Sanu Korumadathil Shaji, Megan Zaman, Bethany Brown, Baojie Zhang, Yumi Yamashita-Kanemaru, Natalie Z.M. Homer, Hosni A.M. Hussein, Qiuchen Zhao, Klaus Okkenhaug, Rahul Roychoudhuri, Abhik Mukhopadhyay, Bidesh Mahata

“…Undertaking in silico structure-based drug repurposing approach, we found posaconazole as an inhibitor of CYP11A1. …”
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