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53421
A basigin antibody modulates MCTs to impact tumor metabolism and immunity
Published 2025-05-01“…Additionally, the antibody alters metabolic profiles in NSCLC-PDOs and T cells. Cryo-EM structural analysis and molecular dynamics simulations reveal that the extracellular Ig2 domain and transmembrane domain of basigin regulate MCT1 activity through an allosteric mechanism. …”
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53422
Comparative genomic analyses reveal different genetic basis of two types of fruit in Maloideae
Published 2025-08-01“…Comparative genomic analyses reveal that allele-specific structural variations result in the loss of EIF1 and/or EIF2, removing the suppression on ACS1 transcription and generating ethylene-dependent fruit. …”
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53423
Network characteristics of the youth’s insomnia and emotional symptoms and their gender differences
Published 2025-06-01“…Significant differences in network structures existed between genders, specifically in network invariance (M = 0.909, p = 0.025) and global strength (males = 75.155, females = 70.527; S = 4.628, p = 0.041). …”
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53424
Trends in intestinal aging: From underlying mechanisms to therapeutic strategies
Published 2025-07-01“…Intestinal aging is central to systemic aging, characterized by a progressive decline in intestinal structure and function. The core mechanisms involve dysregulation of epithelial cell renewal and gut microbiota dysbiosis. …”
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53425
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53426
Os agentes comunitários de saúde nas práticas educativas: potencialidades e fragilidades [Community health workers in educational activities: potentials and weaknesses] [Los agente...
Published 2018-10-01“…Data were obtained by scripted, semi-structured interview and analyzed using content analysis. …”
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53427
Cuidar de pessoas transexuais na ótica dos residentes de enfermagem [Care for transgender people from the nursing resident’s perspective] [Cuidar de personas transexuales en la ópt...
Published 2018-09-01“…Method: an exploratory, qualitative, descriptive study was conducted in 2017, in the urology unit of a university hospital Rio de Janeiro city, by semi-structured interview of 13 first- and second-year nursing residents of the clinical surgery program. …”
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53428
Development of early care for children and their families in the Russian Federation
Published 2022-09-01“…General scientific methods (content analysis, analytical, system-structured, comparative, statistical) and methodological methods of systematization, comparison, generalization, interpretation using the standard Excel-7.0 software package for IBM PC are applied.The object of the study: Children from birth to three years of age who need early care services.The subject of the study: Early care services provided for children of target groups and their families in the constituent entities of the Russian Federation.Results. …”
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53429
Impacto de la gamificación en el aprendizaje y satisfacción de estudiantes de odontología de una universidad peruana
Published 2025-05-01“…The intervention was structured in phases: planning, development and execution, with activities integrated into the theoretical content previously taught in class. …”
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53430
Processo de internação em clínica cirúrgica de um hospital público universitário [Process of hospitalization at surgical-clinic unit at a public university hospital] [Proceso de ho...
Published 2020-08-01“…Data were collected from February to April 2019 using two semi-structured interview scripts. The study was authorized by the research ethics committee. …”
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53431
Lecanemab in clinical practice: real-world outcomes in early Alzheimer’s disease
Published 2025-05-01“…Patients with biomarker-confirmed early-stage AD were screened via a structured referral system, including neurological evaluations, MRI, lumbar puncture or Amyloid-PET, genetic testing, and multidisciplinary team (MDT) consensus discussions. …”
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53432
Factors associated with uptake and acceptability of cervical cancer screening among female sex workers in Northeastern Uganda: A cross-sectional study.
Published 2025-01-01“…Data was collected using structured investigator administered questionnaire and analyzed using Stata statistical software version 15.0 (Stata Corp, Texas, USA). …”
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53433
Soft Power of Higher Education as a Global Leadership Factor
Published 2020-02-01“…In 2018, a series of semi-structured interviews was conducted among Ural Federal University employees, whose responsibilities were related to the promotion of the university on the global educational market. …”
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53434
A medicalização e patologização na perspectiva das mulheres transexuais: acessibilidade ou exclusão social [The medicalization and pathologization in the perspective of transgender...
Published 2017-12-01“…Method: descriptive, qualitative research with 40 transsexual women, performed between December 2016 and April 2017, using semi-structured interviews. Data were submitted to content analysis. …”
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53435
Exploring socio-ecological context and mental health of Ukrainian refugees in Italy through eco-map: a mixed-methods study
Published 2025-01-01“…The socio-ecological context was explored through a semi-structured ecomap distributing individuals into ecomap clusters. …”
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53436
Estàndards de formació: contingut, confecció i implementació
Published 2006-01-01“…Thus, although they constitute teaching objectives this is not in the sense of structured scientific knowledge of distinct subjects; rather they describe a set of aptitudes, known as competencies, which enable achievements of interest to be made in different areas. …”
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53437
Screening and Management of Obstructive Sleep Apnea and Daytime Sleepiness Among Professional Drivers in Tunisia: Protocol for a Machine Learning Study
Published 2025-08-01“…Participants will receive a structured questionnaire to evaluate five main outcomes: the likelihood of OSA, EDS, drowsy driving, related sleepiness near misses and accidents, as well as work productivity. …”
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53438
The differences in temperament–character traits, suicide attempts, impulsivity, and functionality levels of patients with bipolar disorder I and II
Published 2016-01-01“…Filiz Izci,1 Ebru Kanmaz Findikli,2 Serkan Zincir,3 Selma Bozkurt Zincir,4 Merve Iris Koc4 1Department of Psychiatry, School of Medicine, Istanbul Bilim University, Istanbul, 2Department of Psychiatry, School of Medicine, Kahramanmaras Sutcu Imam University, Kahramanmaras, 3Department of Psychiatry, Kocaeli Gölcük Military Hospital, Kocaeli, 4Department of Psychiatry, Erenköy Training and Research Hospital for Psychiatric and Neurological Disorders, Istanbul, Turkey Background: The primary aim of this study was to compare the differences in temperament-character traits, suicide attempts, impulsivity, and functionality levels of patients with bipolar disorder I (BD-I) and bipolar disorder II (BD-II).Methods: Fifty-two BD-I patients and 49 BD-II patients admitted to Erenköy Mental and Neurological Disease Training and Research Hospital psychiatry clinic and fifty age- and sex-matched healthy control subjects were enrolled in this study. A structured clinical interview for Diagnostic and Statistical Manual of Mental Disorders, 4th Edition Axis I Disorders, Temperament and Character Inventory, Barrett Impulsiveness Scale-11 (BIS-11), Hamilton Depression Inventory Scale, Young Mania Rating Scale, and Bipolar Disorder Functioning Questionnaire (BDFQ) were administered to patients and to control group.Results: No statistically significant difference in sociodemographic features existed between the patient and control groups (P>0.05). …”
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53439
Understanding and Overcoming Negative Attitudes That Hinder Adoption of Reablement in Dementia Care: An Explorative Qualitative Study
Published 2025-06-01“…This study aimed to explore the negative attitudes that hinder the adoption of reablement and to identify strategies to mitigate these factors.Methods: An exploratory qualitative approach involving semi-structured interviews was adopted. Interviews were conducted with reablement and/or dementia experts in five countries, namely Australia, Denmark, the Netherlands, Sweden, and the United Kingdom. …”
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53440
Comorbidade psiquiátrica diminui a qualidade de vida de pacientes com enxaqueca crônica Psychiatric comorbidities decrease quality of life in chronic migraine patients
Published 2007-09-01“…METHOD: Fifty patients with chronic migraine diagnosed according to the International Headache Society (2004) were interviewed and met diagnostic criteria for mental disorders, according to the structured interview SCID-I/P and were evaluated by the SF-36 Health Survey questionnaire. …”
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