A Multiphysics Dataset Generation Procedure for the Data-Driven Modeling of Traction Electric Motors by Simone Ferrari, Luigi Solimene, Riccardo Torchio, Costanza Anerdi, Fabio Freschi, Luca Giaccone, Gianmarco Lorenti, Francesco Lucchini, Piergiorgio Alotto, Gianmario Pellegrino, Maurizio Repetto

“…., electromagnetic, thermal, structural, etc.) can no longer be neglected, even in preliminary designs. …”
Get full text

A large C-terminal Rad52 segment acts as a chaperone to Form and Stabilize Rad51 Filaments by Emilie Ma, Fadma Lakhal, Eleni Litsardaki, Myriam Ruault, Maxime Audin, Natacha Levrier, Emilie Navarro, Mickaël Garnier, Laurent Maloisel, Jordane Depagne, Clémentine Brocas, Aurelien Thureau, Didier Busso, Xavier Veaute, Raphaël Guerois, Angela Taddei, Françoise Ochsenbein, Eric Coïc

“…The molecular basis of these two Rad52 functions remains unclear. Our integrative structural analyses of the Rad51-Rad52 interaction, combining NMR, SAXS, and modeling, reveal that an 85-residue segment of Rad52, conserved in fungi, folds upon binding to a broad surface of a Rad51 monomer. …”
Get full text

Targeted degradation of cell surface proteins through endocytosis triggered by cell-penetrating peptide-small molecule conjugates by Wanyi He, Congli Chen, Jiwei Zheng, Yanyan Li, Huaihuai Shi, Yimin Zhou, Meiqing Li, Ping Gong, Ke Liu, Ximing Shao, Xiaojun Yao, Hongchang Li, Liang Chen, Lijing Fang

“…Additionally, simpler structural design and broader therapeutic window for CPPTACs are expected since CPPs-mediated endocytosis and lysosomal degradation do not necessitate the three-component binding model typically required by other heterobifunctional degraders. …”
Get full text

Sulphanilamide degradation by undoped and copper doped ZnO, and ferromagnetic properties of fresh, aged, and heat-treated aged ZnO by Daphne Mary John, Sreerag Kaaliveetil, Yadhu J. Nair, S. Sruthy, P. Lasya, Ramanujam Brahmadesam Thoopul Srinivasa Raghava, G. Sivasubramanian, K.M. Sreedhar, K.M. Sreekanth

“…The synthesized samples were characterized by XRD and then FTIR techniques for structural besides compositional analysis. The approximate value of bandgap found out by NBE values of PL spectra showed a decrease in bandgap with doping. …”
Get full text

CCL5 Induces a Sarcopenic-like Phenotype via the CCR5 Receptor by Francisco Aguirre, Franco Tacchi, Mayalen Valero-Breton, Josué Orozco-Aguilar, Sabrina Conejeros-Lillo, Josefa Bonicioli, Renata Iturriaga-Jofré, Daniel Cabrera, Jorge A. Soto, Mauricio Castro-Sepúlveda, Marianny Portal-Rodríguez, Álvaro A. Elorza, Andrea Matamoros, Felipe Simon, Claudio Cabello-Verrugio

“…The participation of CCR5 was evaluated using the antagonist maraviroc (MVC). Protein and structural analyses were performed. The results showed that TA overexpression of CCL5 led to sarcopenia by reducing muscle strength and mass, muscle-fiber diameter, and sarcomeric protein content, and by upregulating E3-ligases. …”
Get full text

Fe-Cu-loaded γ-Al2O3 as an efficient heterogeneous Fenton catalyst for the advanced treatment of petrochemical wastewater by Shiqi Jiang, Changyong Wu, Qi Huang, Yin Yu, Peijian Zhang, Chenjie Wang, Xiyan Ou, Min Xu

“…Characterization techniques (SEM, BET, XRD, XPS) confirmed the structural features, while EPR and quenching experiments revealed that ·OH and HO2− were the dominant reactive species. …”
Get full text

Multifunctional microneedle-mediated photothermo-gas-ion synergic therapy accelerates MRSA infacted diabetic wound healing by Shihao Deng, Yunhao Tai, Chenxu Liu, Kenan Sun, Shaoze Lan, Liu Yang, Canming Ye, Li Huang, Runhuai Yang, Haisheng Qian, Jun Li

“…Secondly, the microneedles employ PH-responsive Zn2+, H2S release, and photothermal therapy to disrupt the structural integrity of Methicillin-Resistant Staphylococcus Aureus (MRSA) and dismantle the dense biofilm produced by this pathogen. …”
Get full text

Biopharmaceutical profiling of anti-infective sanggenons from Morus alba root bark for inhalation administration by Jacqueline Schwarzinger, Sigrid Adelsberger, Karin Ortmayr, Sarah Luise Stellnberger, Ammar Tahir, Gabriela Hädrich, Verena Pichler, Judith M. Rollinger, Ulrike Grienke, Lea Ann Dailey

“…To assess the suitability of MDAAs for inhalation administration, physicochemical (e.g. pH, pKa, logP, pH-dependent solubility) and biopharmaceutical (epithelial cytotoxicity, permeability, and uptake) properties of two bioactive MDAA stereoisomers sanggenon C (SGC) and sanggenon D (SGD) were evaluated as isolated natural compounds and within parent extracts (MA21, MA60). Despite their structural similarity, SGD exhibited a 10-fold higher solubility than SGC across pH 1.2–7.4, with slight increases at neutral pH. …”
Get full text

Production process, rheology, and sensory characterization of Algerian porridge and flatbread derived from Arum italicum tubers by Hayat Bourekoua, Radia Ayad, Hamida Mahroug, Fairouz Djeghim, Rayene Belmouloud, Aya Louifi, Alla Eddine Mansouri, Anis Chikhoune

“…This research aims to contribute to this field and focuses on the comprehensive analysis of Arum italicum tuber powder, encompassing physicochemical and structural characterization. Additionally, it explores the traditional making processes of products derived from these tubers. …”
Get full text

Precision computerised cognitive behavioural therapy (cCBT) intervention for adolescents with depression (SPARX-UK): protocol for the process evaluation of a pilot randomised contr... by Charlotte Lucy Hall, Chris Hollis, Kareem Khan, Peter Fonagy, Kirsty Sprange, Cathy Creswell, Yi Yang, Vibhore Prasad, Kapil Sayal, Nitish Jawahar, Ellen Townsend, Dorothee Auer, Praveetha Patalay, Aja Murray, Yvonne Kelly, Boliang Guo, Christopher R Tench, Paul Stallard, Louise Arseneault, Sieun Lee, Sally Merry, Charlotte Hall, Jo Gregory, Rory O’Connor, Emma Nielsen, Edmund Sonuga-Barke, Hannah Wright, Petr Slovak, Emily Lloyd, Josimar De Alcantara Mendes, Carolyn Ten Holter, Marina Jirotka, Aaron Kandola, Sonia Livingstone, Kasia Kostryka-Allchorne, Jake Bourgaize, Mariya Stoilova, Marianne Etherson, Chris Greenhalgh, Jim Warren, Vajisha Wanniarachchi, Kevin Glover, Mathijs Lucassen, Karolina Stasiak, Camilla Babbage, Adam Parker, Joanna Lockwood, Elvira Perez Vallejos, Rebecca Woodcock, Sarah Doherty, Lucy-Paige Willingham, Camilla May Babbage, Matthew Jeffery, Peiyao Tang, Holly Griffiths, Lily Roberts, A. Jess Williams, Lucy Hitcham

“…This will include analysing data usage of participants in the intervention arms; purposively sampled, semi-structured interviews of adolescents, parents/guardians, eCoaches and clinicians/practitioners from the SPARX-UK trial; and analysis of qualitative comments from a survey from those who dropped out early from the trial. …”
Get full text

Salinity tolerance in resting cysts of colpodid ciliates: Comparative transcriptomics analysis and chemical analysis of cyst walls to investigate their tolerance capability by Ryota Saito, Hiroki Yamanobe, Kazuma Yabuki, Tomohiro Suzuki, Takeru Saito, Shuntaro Hakozaki, Manfred Wanner, Ryota Koizumi, Tatsuya Sakai, Maribet Gamboa, Toshihiko Tanaka, Akiko Ono, Hoa Thanh Nguyen, Yuta Saito, Tetsuya Aoyama, Katsuhiko Kojima, Futoshi Suizu, Kozo Watanabe, Yoichiro Sogame

“…The resting cyst forms cyst-specific cellular structure known as the cyst wall. The outer shell-like layer, called the ectocyst, while the inner multiple layers, known as the endocyst. …”
Get full text

SET OF ORGANIZATIONALLY-DIDACTIC CONDITIONS OF THE MODEL OF STUDENTS’ AUTONOMY DEVELOPMENT SYSTEM IMPLEMENTATION by Roman A. Popov

“…The first organizational-didactic condition is usage of the mechanisms for the didactic structuring of the educational information content for its autonomous intake by students. …”
Get full text

The Role of Risk Factor in the Surgical Treatment of Hemorrhagic Stroke by V. G. Dashyan, I. M. Godkov, V. A. Khamurzov, R. Yu. Kryachev, A. A. Grin, V. V. Krylov

“…The following types of operations were performed: open removal of the ICH in 271 (54.2%) patients, puncture aspiration and local fibrinolysis of the ICH in 98 (19.6%) cases, endoscopic aspiration of the ICG in 131 (26.2%) patients.RESULTS The risk factors for lethal outcome in HT surgery are the age of patients older than 50 years (χ2=13.9, p<0.04), the volume of cerebral hemispheres more than 50 cm3 (χ2=7.8, p<0.01), the total volume of ICH and perifocal edema more than 100 cm3 (χ2=9.1, p<0.01), transverse dislocation of the median structures of the brain more than 5 mm (χ2=32.2, p<0.0001), axial dislocation of the brain (χ2=16 ,1, p<0.02), BP before surgery higher than 160 mm Hg (χ2=21.9, p<0.002), presence of IVH (χ2=36.9, p<0.00001), AOH (χ2=28.0, p<0.0001), surgery time — the first day after hemorrhage (χ2=64.4, p<0.00001), residual volume of ICH after surgery more than 15 cm3 (χ2=4.0, p<0.05) and recurrence of ICH (χ2=33.1, p<0.00001). …”
Get full text

Spatiotemporal evolution of interseismic coupling and stress accumulation near an asperity on a vertical strike-slip fault: Insights from three-dimensional viscoelastic numerical s... by LI Yebo, HUANG Luyuan, YAO Rui, TIAN Yiwei, YANG Shuxin

“…Overall, this study emphasizes the intricate interactions between fault dynamics and geological structures, and highlights the significance of detailed modeling for understanding earthquake mechanisms. …”
Get full text

Simulation of daylight in the classroom, using an adaptive shell (a case study of a classroom in the city of Yazd) by Narmin Khairy, Mostafa Khairy

“…Electronic science and knowledge of natural structures have also provided many possibilities to architects. …”
Get full text

Paleogeography and regional interpretation of facies in Tirgan Formation, west of Kopet-Dagh sedimentary basin, northeast of Iran by Atefeh Chenarani, Meysam Shafiee Ardestani, Mohamad Vahidinia

“…Estarkhi section), the Tirgan Formation includes in siliciclastic deposits with some marine marls, in that the detrital sediments was carried to the foreland basin as a result of erosion of high structures. In the same time, the western parts of the study area was covered by deposits belonging to a tidal-flat depositional setting, representing a deepening trend from the East towards the West of the area. …”
Get full text

Intrinsic ferroelectric CuVP2S6 for potential applications in neuromorphic recognition and translation by Chunyu Zhao, Weikang Dong, Yang Yang, Hongbin Yu, Jingyi Duan, Denan Kong, Kangshu Li, Xiaocang Han, Chao Yun, Tingjun Wang, Ping Wang, Yang Zhao, Jijian Liu, Qingmei Hu, Lin Jia, Ying Zhang, Hui Ai, Shanshan Wang, Dian Li, Tianyu Zang, Yao Guo, Xueyun Wang, Xiaoxu Zhao, Yao Zhou, Jiadong Zhou

Get full text

Algoritmo para generar formulas de características geométricas de las secciones planas, su implementación en DERIVE // Algorithm for the calculation of the geometric characteristic... by Rolando Rivero-Galán

“…</span></p><p><span style="font-family: Calibri; font-size: small;">______________________________________________________________</span></p><strong><span style="font-family: Calibri,Bold; font-size: small;"><strong><span style="font-family: Calibri,Bold; font-size: small;"><p>Abstract</p></span></strong></span></strong><span style="font-family: Calibri; font-size: small;"><span style="font-family: Calibri; font-size: small;"><p>In the sphere of the design of structures, is relative frequency the calculation of certain</p><p>characteristic or geometric properties of plane sections, like: the area of a traverse section, the</p><p>center of gravity, a moment of inertia or more general the determination of some geometric</p><p>characteristic defined by a double integral extended in the region of the plane that occupies the</p><p>section, piece or element.…”
Get full text

Research progress of fuel ethanol refining and life cycle carbon footprint by Pan LI, Lulu ZHANG, Hai CHEN, Xingguo WU, Wei CHEN, Jing BAI, Chun CHANG, Junhao HU

“…Power consumption is a major contributor to acidification potential and global warming potential, indicating a need for new technologies or alternative power structures can be developed to reduce environmental impact. …”
Get full text

Development status and key technologies of deep-sea towing autonomous underwater vehicles by Guanyu LU, Tiedong ZHANG, Zhenglin LI, Dapeng JIANG, Ming LEI, Wanzhen LUO

“…Regarding key technologies, the overall design of towing AUVs is complex and involves multiple aspects, such as the design and layout of various components. Different system structures and load-mounting positions must be considered, and multi-disciplinary design optimization can improve design efficiency and quality. …”
Get full text