NEXN deficiency leads to dilated cardiomyopathy in human pluripotent stem cell-derived cardiomyocytes by Mengqi Jiang, Xi Chen, Yuanxiu Song, Mingyu Wei, Jixiang Cao, Wenjing Lu, Feng Lan, Yun Bai, Ming Cui

“…Conclusion We demonstrated that NEXN was one of the important components in maintaining the structure and function of cardiomyocyte junctional membrane complexes (JMCs), excitation-contraction coupling and energy metabolism of cardiomyocytes, while the loss of its function would lead to DCM. …”
Get full text

FEATURES OF AUDIT OF SUSTAINABILITY REPORTING: EMPIRICAL EXPERIENCE OF THE EUROPEAN UNION COUNTRIES by Костянтин Безверхий, Ірина Парасій-Вергуненко, Олексій Пилипенко, Олександр Юрченко, Микола Матюха, Наталія Поддубна

“…The standards applied to the preparation and assurance of sustainability reports were reviewed, as they serve as the basis for the preparation and assurance of such reports. The structure and main features of the legal framework for disclosure of financial and non-financial information were outlined. …”
Get full text

GaN-Based Generic Bifunction LED for Potential Duplex Free-Space VLCs by Lilin Liu, Xiangying Zhang, Zhenkun Sun, Bing Yan, Dongdong Teng, Gang Wang

“…A generic bifunction GaN light-emitting diode (LED) structure, which has a 300&#x00A0;nm <italic>n^&#x002B; -ZnO</italic> epitaxial layer grown on a standard GaN LED epistack and a mesa size of <inline-formula> <tex-math notation="LaTeX">$200\, \mathrm{\mu} {\rm{m\, \times \, 600\, }}\mathrm{\mu} {\rm{m}}$</tex-math> </inline-formula>, exhibits a peak responsivity of 450&#x00A0;mA&#x002F;W to purple lights (380&#x2013;400&#x00A0;nm) under zero bias and a narrow bandpass of around 60&#x00A0;nm. …”
Get full text

A federated learning-based privacy-preserving image processing framework for brain tumor detection from CT scans by Abdullah Al-Saleh, Ghanshyam G. Tejani, Shailendra Mishra, Sunil Kumar Sharma, Seyed Jalaleddin Mousavirad

“…ResNet-50 and capsule networks are incorporated to achieve better feature extraction and maintain the structure of images’ spatial data. To get the best results, the hybrid Gorilla Badger optimization algorithm (HGBOA) is applied for selecting the key features. …”
Get full text

An intranasal ASO therapeutic targeting SARS-CoV-2 by Chi Zhu, Justin Y. Lee, Jia Z. Woo, Lei Xu, Xammy Huu Wrynla, Livia H. Yamashiro, Fei Ji, Scott B. Biering, Erik Van Dis, Federico Gonzalez, Douglas Fox, Eddie Wehri, Arjun Rustagi, Benjamin A. Pinsky, Julia Schaletzky, Catherine A. Blish, Charles Chiu, Eva Harris, Ruslan I. Sadreyev, Sarah Stanley, Sakari Kauppinen, Silvi Rouskin, Anders M. Näär

“…We identify an LNA ASO binding to the 5′ leader sequence of SARS-CoV-2 that disrupts a highly conserved stem-loop structure with nanomolar efficacy in preventing viral replication in human cells. …”
Get full text

A Lightweight Transformer-Based Spatiotemporal Analysis Prediction Algorithm for High-Dimensional Meteorological Data by Yinghao Tan, Junfeng Wu, Yihang Liu, Shiyu Shen, Xia Xu, Bin Pan

“…SA-Fit shortens training time and significantly reduces model parameters while using the Transformer structure to ensure prediction accuracy.…”
Get full text

Life in sympatry: coexistence of native Eurytemora affinis and invasive Eurytemora carolleeae in the Gulf of Finland (Baltic Sea) by Natalia Sukhikh, Anissa Souissi, Sami Souissi, Anne-Catherine Holl, Nikolaos V. Schizas, Victor Alekseev

“…In this study, we monitored the distribution area of the invasive copepod species in European waters, as well as the population structure of (native) E. affinis and (invasive) E. carolleeae, from 2006 to 2018 in the Gulf of Finland. …”
Get full text

Analysis of Hybrid Agile Project Management in the Telecommunications Industry by Nehir Tokgöz, Svitlana Samoylenko, Shiv Kumar Tripathi, Betül Aydin

“…This approach provided comprehensive insights into the case company’s agile practices, highlighting the complexity of its organizational structure and the impact on project management. The thematic analysis of these interviews emphasized the hybrid approach's role in balancing regulatory, security, and business needs. …”
Get full text

Genetic Mechanism and Identification Method of Low Resistivity Tight Conglomerate Oil Layer in Mahu Depression by CAO Zhifeng, LINGHU Song, WANG Xianhu, WANG Zhenlin, ZHANG Wei, ZHANG Yanli

“…Due to the undercompaction of mudstone, overpressure reservoir is formed, and the formation overpressure improves the pore structure of reservoir and develops micro-cracks, which will enhance the conductivity of formation. …”
Get full text

Effects of Pregelatinization on the Physicochemical Properties of Corn Grits and the Quality of Cooked Waxy Corn Wrapped in Plant Leaves by Yi Wang, Ruixuan Li, Yijiao Yan, Wanyi Niu, Yue Wang, Mingyi Shen, Ruifang Wang, Li Cheng

“…The modified grits were characterized using Rapid Visco Analyzer (RVA), differential scanning calorimetry (DSC), X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR), and scanning electron microscopy (SEM) to analyze pasting properties, retrogradation behavior, crystallinity, molecular structure, and morphology. The results showed that pregelatinization significantly reduced setback viscosity (from 274.83 to 154.52 mPa·s), crystallinity (from 11.12% to 3.62%), and retrogradation tendency while improving solubility, swelling power, and water-holding capacity. …”
Get full text

Prediction of mild cognitive impairment using blood multi-omics data by Daniel Frank Zhang, Daniel Frank Zhang, Cigdem Sevim Bayrak, Qi Zeng, Qi Zeng, Qi Zeng, Minghui Wang, Bin Zhang, Bin Zhang, Bin Zhang, Bin Zhang

“…We demonstrated, for the first time, that data at a genome structure level such as CNVs could be as informative as gene expression data to classify MCI patients from normal controls. …”
Get full text

Diversity and Key Organisms in the Biocrust of a Tropical Granite-Gneiss Rocky Outcrop by Mateus Fernandes Oliveira, Cleber Cunha Figueredo, Adaíses Simone Maciel-Silva

“…This study examines biocrust composition in a granite-gneiss outcrop in a rural landscape in Southeastern Brazil, identifying microhabitats and analyzing co-occurrence patterns and community structure. We recorded eleven bryophyte species and one diatom species, while six cyanobacteria, three charophytes, and two chlorophytes were identified at the genus level. …”
Get full text

Effects of Five Coarse Cereals on Glycemic Index and Edible Quality of Steamed Bread by ZHAO Chen-xu, QI Wen-tao, SONG Ge, HONG Yu, FANG Wei, HUANG Zheng-yu, WANG Yong

“…The sensory quality declined, with lower sensory scores, the internal structure gradually became rough, the hardness increased and the brightness decreased. …”
Get full text

A potent and selective reaction hijacking inhibitor of Plasmodium falciparum tyrosine tRNA synthetase exhibits single dose oral efficacy in vivo. by Stanley C Xie, Chia-Wei Tai, Craig J Morton, Liting Ma, Shih-Chung Huang, Sergio Wittlin, Yawei Du, Yongbo Hu, Con Dogovski, Mina Salimimarand, Robert Griffin, Dylan England, Elisa de la Cruz, Ioanna Deni, Tomas Yeo, Anna Y Burkhard, Josefine Striepen, Kyra A Schindler, Benigno Crespo, Francisco J Gamo, Yogesh Khandokar, Craig A Hutton, Tayla Rabie, Lyn-Marié Birkholtz, Mufuliat T Famodimu, Michael J Delves, Judith Bolsher, Karin M J Koolen, Rianne van der Laak, Anna C C Aguiar, Dhelio B Pereira, Rafael V C Guido, Darren J Creek, David A Fidock, Lawrence R Dick, Stephen L Brand, Alexandra E Gould, Steven Langston, Michael D W Griffin, Leann Tilley

“…We confirm that ML471 is a reaction hijacking inhibitor that is converted into a tight binding Tyr-ML471 conjugate by the PfTyrRS enzyme. A crystal structure of the PfTyrRS/ Tyr-ML471 complex offers insights into improved potency, while molecular docking into UAE provides a rationale for improved selectivity.…”
Get full text

Research of Electrophysical Properties of Thin Gate Dielectrics Obtained by Rapid Thermal Processing Method by N. S. Kovalchuk, A. A. Omelchenko, V. A. Pilipenko, V. A. Solodukha, S. V. Demidovich, V. V. Kolos, V. A. Filipenia, D. V. Shestovski

“…Carrying out photonic processing in anitrogen atmosphere at high temperatures of procedures for proceeding of the restructuring of the structure of the dielectric layer. For insulators obtained by a three-stage process with final processing in N2, an increase in dielectric strength and breakdown voltage by 1 V and 3.3 MV/cm, respectively, is observed in comparison with dielectrics, obtained by a two-stage process. …”
Get full text

Electro–optic coupling modulation on persistent photoconductivity and memristive states in thin-film devices with MoOx/ZnO heterostructured electrodes by Fushun Li, Xuanhe Li, Jiale Su, Zhenxin Yang, Haikun Zhu, Jinquan Huang, Deng-Ke Wang, Zheng-Hong Lu, Qiang Zhu

“…In this study, we introduced a concise thin-film device with an asymmetric MoOx/ZnO heterojunction electrode structure (HES) fabricated using an economical solution process. …”
Get full text

Trends of antibiotic resistance of Helicobacter pylori in Moscow by Igor V. Maev, Dmitry N. Andreev, Aleksei K. Fomenko, Mikhail S. Podporin, Svetlana V. Lyamina, Andrew V. Zaborovsky, Irina N. Khimina, Sergei V. Cheremushkin, Armine S. Bagdasarian, Natalia V. Cheremushkina, Elena G. Lobanova, Victor N. Tsarev, Oleg V. Zayratyants

“…Among strains collected from 2015 to 2019 (n=28), resistance to AMC was 0.0%, CLR 10.71%, TET 0.0%, and MET 50.0%. The structure of antibiotic resistance of strains collected from 2020 to 2024 (n=95) was as follows: AMC – 6.32%, CLR – 17.89%, TET – 4.21%, MET – 45.26%. …”
Get full text

The effect of Badland erosion on the loss of organic matter and changes in some soil properties in dry areas of Khuzestan province (Shoushtar Darb Khazineh basin) by Kamran Mohsenifar, Ali Helfi, Ebrahim Pnahpour

“…The results demonstrated the positive effect of watershed operations on the improvement of the soil condition in the protected areaConclusions: Due to the reduction of vegetation cover, organic matter, destruction of soil structure, and reduction of stability of soil particles, the soil erodibility index increases.…”
Get full text

Enhancing the Efficiency and Schedule of Solar Thermal Power Plants by Utilizing Thermal Storage Devices to Minimize Carbon Emissions by Lingeswaran P., Yadav Shailendra Kumar, Ganesh Babu L., Magesh Babu D., Karuppannan Anand, Iftekhar Hussain Beporam, Nanthakumar S.

“…The renewable energy method of photo thermal power generation has great promise for future advancements. The core structure and characteristics of energy flow of photo thermal power plants are often overlooked when operating and scheduling these facilities. …”
Get full text

The Plant Communities of the Class <i>Isoëto-Nanojuncetea</i> in Sardinia by Salvatore Brullo, Gianluigi Bacchetta, Salvatore Cambria, Valeria Tomaselli, Gianpietro Giusso del Galdo, Pietro Minissale, Giovanni Rivieccio, Maria Carmela Caria, Simonetta Bagella

“…It groups plant communities floristically characterized by a rich set of annual hygrophytes or more rarely hemicryptophytes and geophytes, which are also physiognomically, ecologically, and structurally well differentiated. Within this class, two orders are recognized in Sardinia, such as <i>Isoëtetalia</i> and <i>Nanocyperetalia</i>, which are represented by several alliances. …”
Get full text