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98981
Conserved function of bat TBK1 in activating innate immunity against RNA viruses: insights into the innate immune response in bats
Published 2025-07-01“…Co-expression of bat TBK1 with bat IRF1/3/7 can facilitate the upregulation of IFNβ mediated by bat TBK1, implying the activation signals potentially can be transmitted from bat TBK1 to IRF1/3/7, and then promote IFNβ production. Structurally, protein kinase domain (PKD), ubiquitin-like domain (ULD), and coiled-coil domain 1 (CCD1) are essential domains for bat TBK1 to function normally. …”
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98982
ADAMTS2: More than a procollagen N-proteinase
Published 2025-11-01“…This narrative review provides an in-depth overview of the discovery, structure, regulation, and enzymatic role of ADAMTS2, its role in fibrillar collagen maturation and in dEDS pathogenesis, as well as its newly discovered substrates and its potential role in complex disorders.…”
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98983
Casting of Aluminium Foam with Defined Porosity Using DoE
Published 2025-02-01“…To achieve these properties, the structure of the foam is important. The number, shape, regularity and distribution of pores are of great importance. …”
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98984
Evolution of the Three Spectral Components in the Prompt Emission of GRB 240825A
Published 2025-01-01“…The multisegment broken power-law feature observed in the flux lightcurves suggests the presence of an early afterglow in the keV–MeV band and hints at a possible two-jet structure. Furthermore, the observed transition from positive to negative on the spectral lag can be interpreted as misalignment in the cross-correlation function analysis of pulses, which is caused by evolution of the soft and hard components.…”
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98985
Orphan drugs and the principles of their marketing authorization procedures and clinical use
Published 2018-02-01“…One of the most complicated issues of modern medicine is diagnosis, treatment and prevention of rare diseases. In the structure of rare diseases the vast majority accounts for genetically determined disorders. …”
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98986
Multiple solitary fibrous tumors of the pleura with multicentric and unilateral involvement: a case report
Published 2023-07-01“…These tumors were arose from the pleura with a fibrous capsule structure. Their pathological findings were identical to the initial tumor without evidence of malignant transformation. …”
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98987
The diffusion characteristics of Fe-Ti during shear-extrusion solid-state bonding and the influence of the level of deformation
Published 2025-09-01“…Microstructural analysis confirmed effective metallurgical bonding achieved above 112 % deformation, forming a strip-like interface structure composed of FeTi and Fe2Ti intermetallic compounds. …”
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98988
Design of a fully autonomous oil sampling collection robot system for substation oil-filled equipment
Published 2025-07-01“…The robot has been successfully applied in a demonstration of oil sampling for oil-filled equipment at a 1000 kV ultra-high voltage substation, thereby validating the reliability of the robot’s structure and functionality.…”
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98989
Stromal vascular fraction in canine osteoarthritis: advantages, applications, and insights for veterinary practitioners
Published 2025-05-01“…The heterogeneous cellular structure of SVF allows it to achieve joint improvement through both cell-based tissue restoration and signaling functions that benefit joint health. …”
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98990
Near-zero nonlinear error pressure sensor based on piezoresistor sensitivity matching for wind tunnel pressure test
Published 2025-06-01“…By adjusting the piezoresistors' structure and position on the sensing membrane, four piezoresistors with equal sensitivity are obtained, and theoretical quasi-zero nonlinear error is achieved. …”
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98991
Methodological aspects of training future technology teachers for project activities in the field of design and decorative arts
Published 2024-06-01“…It is noted that project activity is defined as a way of achieving specific goals through planning, organization and management, which includes a clear structure and implementation methodology. The development of the methodology for the organization of project activities of future technology teachers in the field of design and decorative and applied arts is based on a clear understanding of the features of the educational components of this direction, the possibilities of adapting the educational process to practical tasks. …”
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98992
Temporal and spatial evolution of global major grain trade patterns
Published 2024-03-01“…This study uses a complex network analysis model to examine the evolution and trends of the global major grain trade from 1990 to 2020, focusing on network topology, centrality ranking, and community structure. There are three major findings. First, the global major grain trade network has expanded in scale, with a growing emphasis on diversification and balance. …”
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98993
Im/mobility in a disruptive time: the impact of Covid-19 on the size and directional flow of international student mobility
Published 2025-03-01“…Abstract The share of internationally mobile students has risen exponentially for the last two decades until the disruptive COVID-19 period, leading to a more diverse and multipolar network structure. However, the COVID-19 pandemic has caused restrictions across the globe. …”
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98994
Longitudinal Cell Tracking and Simultaneous Monitoring of Tissue Regeneration after Cell Treatment of Natural Tendon Disease by Low-Field Magnetic Resonance Imaging
Published 2016-01-01“…Clinical and ultrasonographical findings as well as T2-weighted MRI series indicated a gradual improvement of tendon function and structure.…”
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98995
Non-Abelian domain walls and gravitational waves
Published 2025-04-01“…We estimate the resulting gravitational wave spectrum and find that, thanks to their rich vacuum structure, non-Abelian domain walls manifest in a very interesting and complex phenomenology.…”
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98996
Coupling of straw returning and nitrogen-water integration on rice nitrogen recovery and soil carbon pool
Published 2025-08-01“…The optimized carbon pool structure established the foundation for integrated water-nitrogen management. …”
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98997
Formation and Evolution Simulations of Saturn, Including Composition Gradients and Helium Immiscibility
Published 2025-01-01“…At 4.57 Gyr, the model, proceeding outward, has the following structure: (i) a central core composed of 100% heavy elements and molecules, (ii) a region with a decreasing heavy-element mass fraction, down to a value of 0.1, (iii) a layer of uniform composition with the helium mass fraction Y enhanced over the primordial value, (iv) a helium rain region with a gradient in Y , (v) an outer convective, adiabatic region with uniform composition in which Y is reduced from the primordial value, and (vi) the very outer layers where cloud condensation of the heavy elements occurs. …”
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98998
Current Status, Challenges and Future Perspectives of Operation Optimization, Power Prediction and Virtual Synchronous Generator of Microgrids: A Comprehensive Review
Published 2025-07-01“…First, this review describes the concept and structure of microgrids, including components such as distributed power sources, energy storage devices, energy conversion devices and loads. …”
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98999
Exploring the inhibitory effect and mechanism of 3,4,5-trihydroxybiphenyl on α-glucosidase: an integrated experimental and computational approach
Published 2025-07-01“…The interaction between THB and α-glucosidase induced significant changes in the enzyme’s microenvironment and secondary structure. The primary driving force for the binding of THB to α-glucosidase was hydrogen bonding. …”
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99000
Molecular phylogeny of the wolf spider subfamily Allocosinae in South America (Araneae: Lycosidae)
Published 2025-07-01“…Analyses using both maximum likelihood and Bayesian frameworks were conducted to examine internal relationships and phylogenetic structure and to infer a timeline of diversification. …”
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