KDM6A downregulation promotes tumor-prone cytokines expression in cancer-associated fibroblasts by activating enhancers by Jieying Zhang, Suoyu Xiang, Dan Liu, Xiaomeng Pei, Meng Chen, Yiheng Zhao, Yongbin Wang, Qiong Wang, Lan Kang, Zuoren Yu, Jun Mi, Wujun Xiong

“…Additionally, integrated analysis of ATAC sequencing and RNA sequencing revealed altered chromatin structure during fibroblast activation. CUT-tag sequencing and co-IP assays demonstrate that KDM6A is bound to WDR5, facilitating its association with the COMPASS complex and the polycomb repressive complex at the expected target loci. …”
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Enhanced thermal performance and hydrochloric acid gas (HCl) emission mitigation in ammonium perchlorate (AP)-Based solid propellants with potassium permanganate (KMnO4)/AP dual ox... by Izzat Najmi Yaacob, Ezanee Gires, Adi Azrif Basri, Kamarul Arifin Ahmad, Kamsani Kamal, Nor Afizah Salleh, Suraya Shahedi, Fikri Rasih, Zakwan Azizi, Sharul Sham Dol, Norkhairunnisa Mazlan

“…This novel KMnO4/AP was characterised in terms of morphological structure, elemental analysis, and thermal decomposition properties by using scanning electron microscope (SEM), energy dispersive X-ray analysis (EDX), and differential scanning calorimetry (DSC) and thermogravimetry analysis (TGA), respectively. …”
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Preliminary Analysis of a Novel Spaceborne Pseudo Tripe-Frequency Radar Observations on Cloud and Precipitation: EarthCARE CPR-GPM DPR Coincidence Dataset by Zhen Li, Shurui Ge, Xiong Hu, Weihua Ai, Jiajia Tang, Junqi Qiao, Shensen Hu, Xianbin Zhao, Haihan Wu

“…By integrating EarthCARE W-band doppler cloud radar observations with GPM Ku/Ka-band dual-frequency precipitation radar data, this study constructs a novel global “pseudo tripe-frequency” radar coincidence dataset comprising 2886 coincidence events (about one-third of the events detected precipitation), aiming to systematically investigating band-dependent responses to cloud and precipitation structure. Results demonstrate that the W-band is highly sensitive to high-altitude cloud particles and snowfall (reflectivity < 0 dBZ), yet it experiences substantial signal attenuation under heavy precipitation conditions, and with low-altitude reflectivity reductions exceeding 50 dBZ, its probability density distribution is more widespread, with low-altitude peaks increasing first, and then decreasing as precipitation increases. …”
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Effects of high impact exercise on systemic cytokines in women with mild knee osteoarthritis: A 12-month RCT by Ville-Markus Konola, Juhani Multanen, Johanna K. Ihalainen, Jukka E. Hintikka, Timo Jämsä, Hannu Kautiainen, Miika T. Nieminen, Satu Pekkala, Maarit Valtonen, Ari Heinonen

“…The serum cytokine levels, including interleukin-1 alpha (IL-1α), IL-2, IL-4, IL-5, IL-6, IL-10, IL-13, IL-17, interferon-gamma (IFN-γ), and tumor necrosis factor alpha (TNF-α), were determined via multiplex cytokine assays. The cartilage structure of the medial tibial condyle was assessed by MRI T2 mapping. …”
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OsHemA gene, encoding glutamyl-tRNA reductase (GluTR) is essential for chlorophyll biosynthesis in rice (Oryza sativa) by Zhao-qiong ZENG, Tian-zi LIN, Jie-yu ZHAO, Tian-hui ZHENG, Le-feng XU, Yi-hua WANG, Ling-long LIU, Ling JIANG, Sai-hua CHEN, Jian-min WAN

“…With intact thylakoid lamellar structure, the cbd1 plant showed light green leaves and reduced Chl and carotenoids (Cars) content significantly compared to the wild type. …”
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Development of hydrophobic jute fibers reinforced chitosan/guar gum biocomposite film for sustainable food packaging solution by Aminu Abdullahi, Tarangini Korumilli, K. Jagajjanani Rao

“…Microscopic analysis of the cross-sectional structure of the films revealed a dense, compact morphology and FTIR result shows evidence of chemical interaction of the composite components. …”
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Exploring novel roles of lipid droplets and lipid metabolism in regulating inflammation and blood–brain barrier function in neurological diseases by Luo Fu, Luo Fu, Ting Luo, Ting Luo, Zhongnan Hao, Yongli Pan, Yongli Pan, Wenqiang Xin, Lin Zhang, Lin Zhang, Zhuhong Lai, Haitao Zhang, Hua Liu, Wei Wei, Wei Wei

“…The blood–brain barrier (BBB) is a critical structure that maintains the brain’s homeostasis by regulating the transport of molecules and protecting it from harmful substances. …”
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Triclosan exposure induces liver fibrosis in mice: The heterogeneous nuclear ribonucleoprotein A1/pyruvate kinase M2 axis drives hepatic stellate cell activation by Xiao Ni, Ziyun Wei, Yuxuan Peng, Linlin Zheng, Jianing Shang, Fu Liu, Yunwei Li, Jieyu Liu

“…TCS possesses a stable structure, can easily accumulate in the environment, and may have numerous negative impacts on human health. …”
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MAGNETIC RESONANCE TOMOGRAPHY IN SLEEP APNEA SYNDROME DIAGNOSTICS by M. A. Shariya, E. A. Butorova, A. Yu. Litvin, D. V. Ustyuzhanin, Е. М. Elfimova, Sh. B. Gorieva, S. K. Ternovoy, I. E. Chazova

“…To study the specifics of soft tissues surrounding upper airways (STSUA) structure using magnetic resonance tomography (MRI) in patients with obesity and obstructive sleep apnea syndrome (OSAS). …”
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Genetic aspects of nonimmune hydrops fetalis by H. A. Sarkisyan, S. V. Dumova, E. I. Shabelnikova, A. A. Fadeeva, K. S. Zizyukina, I. Yu. Zyablova, A. P. Khokhlova, O. I. Savateeva, D. M. Muscherova, I. V. Zhuravleva

“…This work reflects the etiological structure of nonimmune hydrops fetalis with an emphasis on genetic disorders, and also notes the diagnostic, therapeutic and prognostic features of pregnancy management with nonimmune hydrops fetalis.…”
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Building a collaborative ecosystem across the IDeA-CTR networks in response to a public health emergency by A. Jerrod Anzalone, Sharon Patrick, Amber Abel, Brad Price, Elizabeth Reisher, Kent Ripplinger, Mary Emmett, Ronald Horswell, San Chu, William B. Hillegass, Francisco S. Sy, Brian Melancon, H. Timothy Bunnell, Lucio Miele, Mary Helen Mays, Joseph Keawe‘aimoku Kaholokula, Elizabeth S. Chen, Karen M. Crowley, Indra Neil Sarkar, Susan L. Santangelo, Clifford J. Rosen, Jeremy Harper, David Bard, William Beasley, Sally L. Hodder

“…Methods: We developed an organizational structure across the IDeA-CTRs to improve research productivity in resource-challenged areas of the U.S. …”
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Women’s and girls’ sexual empowerment differs by geographical context: a population-based validation study by Shannon N. Wood, Jessica L. Dozier, Celia Karp, Funmilola M. OlaOlorun, Elizabeth Omoluabi, Rosine Mosso, Pierre Z. Akilimali, Simon Peter Sebina Kibira, Frederick Makumbi, Georges Guiella, Peter Gichangi, Anoop Khanna, Sani Oumarou, Caroline Moreau

“…Findings Final models confirm the theoretical structure of the sexual empowerment measure, including two- dimensions: “existence of choice” and “exercise of choice”, each comprised of three items, with moderate internal consistency ranging from 0.59 to 0.69. …”
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Association mapping for total phenols, total flavonoids and antioxidant activity in a Mesoamerican bean diversity panel by Alison Fernando Nogueira, Alison Fernando Nogueira, Vânia Moda-Cirino, José dos Santos Neto, Jessica Delfini, Daniel Fernando Viana Fagundes, Paul Gepts, Leandro Simões Azeredo Gonçalves

“…After removing SNPs with high linkage disequilibrium, 707 SNPs were retained for population structure analysis. In total, 147 unique QTNs were significant for the three biochemical traits studied (TPC, FLA, and DPPH), of which 41 were detected at least twice by one of the seven multi-locus methods used or in different environments analyzed (Londrina, Guarapuava, and LSmeans). …”
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Left heart function and strain for predicting change in hemoglobin levels in pediatric kidney transplantation recipients by Shufan Yue, Fei Xiao, Rui Fan, Wei Li, Donghong Liu, Fengjuan Yao, Hong Lin, Chenglin Wu, Longshan Liu, Changxi Wang, Jun Li, Cuiling Li, Cuiling Li

“…Echocardiography was used to evaluate the cardiac structure, function, and strain both before and after KTx. …”
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Mechanism of Threshold Voltage Instability in Double Gate &#x03B1;-IGZO Nanosheet TFT Under Bias and Temperature Stress by Muhammad Aslam, Shu-Wei Chang, Yi-Ho Chen, Yao-Jen Lee, Yiming Li, Wen-Hsi Lee

“…Given the demand for CMOS-compatible, ultra-scaled, reliable, and high-performing devices, we fabricate and analyze scaled-channel a-IGZO-TFTs with an optimal double-gate structure, a thin nanosheet-based channel, and an effective high- <inline-formula> <tex-math notation="LaTeX">$\kappa$ </tex-math></inline-formula> dielectric namely HfO2. …”
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Donor-derived myeloid sarcoma in a kidney transplant recipient: clinical case study and relevance of a multidisciplinary approach in therapy and diagnosis by N. A. Chichagova, D. V. Gogolev, D. O. Kuzmin, A. N. Ananyev, A. A. Kutenkov, A.  A. Galkin, T.  B. Kapitulskaya, D. D. Fedotova, I. V. Ulyankina, O. N. Reznik, S. F. Bagnenko

“…Results of morphological study of the removed renal graft with immunohistochemistry (IHC) were obtained. The structure and phenotype of the tumor are consistent with myeloid sarcoma. …”
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Evaluation of dental implant with hydroxyapatite coating by laser-induced hydrothermal synthesis: in vitro and in vivo experimental study by Jung-Tae Lee, Sungtae Kim, Sung-Ho Lee, Dong-Wook Han, Keonhee Lee, Sangyun Lee, Daehyeok Kwon, Kyungwoo Lee, Hojeong Jeon, Tae-Gon Jung, Bongju Kim

“…This study aimed to evaluate both in vitro and in vivo outcomes of implants coated with a nano/micro-assembled hydroxyapatite (HA) structure using a laser-induced single-step coating (LISSC) technique. …”
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Development of Antimicrobial and Antioxidative Chicken Patties Using Liquid-Fermented <i>Ganoderma lucidum</i> and <i>Pleurotus djamor</i> Fruiting Body Biomass by Nur Asyiqin Zahia-Azizan, Chong Shin Yee, Muhammad Ameer Ushidee-Radzi, Zul Ilham, Muhamad Hafiz Abd Rahim, Siva Raseetha, Nazimah Hamid, Adi Ainurzaman Jamaludin, Wan Abd Al Qadr Imad Wan-Mohtar

“…All elemental, FT-IR, and NMR spectroscopy analyses revealed the existence of a comparable beta-glucan polymer structure, linkages, and absorptions when compared to the Laminarin standard. …”
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Ultra-transparent β-Ga2O3:Cr3+ glass-ceramics enabling high-efficiency true-transmission near-infrared light-emitting diodes by Shaoan Zhang, Yi Long, Penghui Zhang, Zaijin Fang, Zhenzhang Li, Huacong Ye, Guojun Zheng, Hong Jia, Jianrong Qiu, Yang Li

“…Near-infrared phosphor-converted light-emitting diodes (NIR pc-LEDs), one of the most promising NIR light sources, have garnered significant attention owing to their compact structure, long lifetime and energy conservation. Despite these advantages, commercial NIR pc-LEDs employing pseudotransmission configurations, where the NIR phosphor and silicone composites are directly coated on blue LED chips, suffer from critical limitations in thermal management that severely deteriorate their NIR output performance. …”
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CARDIOVASCULAR DISEASES REGISTRY (RECVAZA): DIAGNOSTICS, CONCOMITANT CARDIOVASCULAR PATHOLOGY, COMORBIDITIES AND TREATMENT IN THE REAL OUTPATIENT-POLYCLINIC PRACTICE by S. A. Boytsov, M. M. Luk’yanov, S. S. Yakushin, S. Yu. Martsevich, A. N. Vorobyov, A. V. Zagrebelny, K. G. Pereverzeva, E. A. Pravkina, A. D. Deev, E. Yu. Andreenko, A. I. Ershova, A. N. Meshkov, R. P. Myasnikov, S. S. Serdyuk, M. S. Kharlap, E. V. Bazaeva, A. N. Kozminsky, K. A. Moseychuk, E. N. Kudryashov

“…Aim. To study the structure of concomitant cardiovascular and comobid pathology, risk factors in patients with arterial hypertension (AH), coronary heart disease (CHD), with congestive heart failure (CHF) and atrial fibrillation (AF), and to evaluate the quality of diagnostics and treatment in the conditions of real outpatient-polyclinic practice by the Registry in Ryazanskaya region – a RF region with high level of cardiovascular mortality.Material and methods. …”
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