Drought-induced shifts in cowpea rhizoplane bacterial communities across different vegetative and reproductive stages by Durga P.M. Chinthalapudi, Nisarga Kodadinne Narayana, Sujan Poudel, John P. Brooks, Shankar Ganapathi Shanmugam, Raju Bheemanahalli

“…Beta diversity results revealed that genotype and drought significantly influenced microbial community structure across growth stages. Proteobacteria dominated the root zone of the EpicSelect4 genotype, while UCR369 showed an increase in Actinobacteria under drought conditions. …”
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Psychosocial Assessment as a Key Component in an Integrated, Personalized Care Pathway: A Protocol for a Low Back Pain Randomized Controlled Trial by Anna Anselmo, Maria Pagano, Francesco Corallo, Irene Cappadona, Davide Cardile, Fabrizio Russo, Alice Laudisio, Giuseppe F. Papalia, Angelo Quartarone, Rocco S. Calabrò

“…Repeated administration of the questionnaires will allow us to monitor the patient over time, assess any changes in their health status, and structure an intervention tailored to their needs. …”
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Robust production of monovalent bispecific IgG antibodies through novel electrostatic steering mutations at the CH1-Cλ interface by John D. Bagert, Vaheh Oganesyan, Chi-I Chiang, Mike Iannotti, Jia Lin, Chunning Yang, Sterling Payne, Will McMahon, Samuel Edwards, Andrew Dippel, Mark Hutchinson, Fengying Huang, Vineela Aleti, Chendi Niu, Chen Qian, Jessica Denham, Sofia Ferreira, Pallab Pradhan, Mark Penney, Chunlei Wang, Wenhai Liu, Even Walseng, Yariv Mazor

“…Asymmetric monovalent bispecific IgGs (bsIgGs) have the additional advantage of maintaining a native antibody-like structure, which can provide favorable pharmacology and pharmacokinetic profiles. …”
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Integrated neurobehavioral and organ-specific safety profiling of baicalin: acute/subacute toxicity studies by Jiali Yang, Jiali Yang, Jiali Yang, Mengyu Chen, Mengyu Chen, Mengyu Chen, Mengyu Chen, Wan Zhang, Wan Zhang, Jia Liu, Jia Liu, Jing Zhao, Jing Zhao, Xin Ping, Xin Ping, Xin Ping, Ye Lu, Ye Lu, Pei He, Pei He, Lin Pei, Lin Pei, Lin Pei, Lin Pei

“…Histopathological evaluations confirmed non-necrotic liver stress and unchanged hippocampal structure.ConclusionBaicalin showed high acute safety with an LD50 over 4,000 mg/kg in mice, and a subacute no-observed-adverse-effect level (NOAEL) of 2,000 mg/kg, indicating its potential as a neuroprotective agent. …”
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Isobutyrate Confers Resistance to Inflammatory Bowel Disease through Host–Microbiota Interactions in Pigs by Xiuyu Fang, Haiyang Liu, Junling Liu, Yongqing Du, Zihan Chi, Yiqi Bian, Xuan Zhao, Teng Teng, Baoming Shi

“…We established a model of dextran sulfate sodium-induced colitis in pigs, which have gastrointestinal structure and function similar to those of humans; we performed multiomic analysis to investigate the therapeutic effects and potential mechanisms of isobutyrate on IBD at both the animal and cellular levels and validated the results. …”
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Energy absorption and mechanical performance of kenaf yarn/fibreglass mesh/acrylonitrile butadiene styrene composites: Influence of mesh density by Mohamad Yusuf Salim, Muhamad Fauzi Muhammad Fitri, Muhammad Asyraf Muhammad Rizal, Rushdan Ahmad Ilyas, Mohd Haziq Dzulkifli, Shukur Abu Hassan, Abu Bakar Mohd Supian, Muhammad Rizal Razman

“…The best fibreglass mesh structure and density for mechanical performance and lightweight properties are unknown. …”
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Efficiency of using antibacterial coatings on titanium implants in the treatment of gunshot fractures by Denis V. Davydov, Leonid K. Brizhan, Artur A. Kerimov, Igor V. Khominets, Kazbek K. Bekshokov, Andrey A. Gritsyuk, Evgeniy A. Kukushko, Vladimir D. Besedin

“…Introduction High risk of infectious complications in gunshot wounds remains a pressing issue in military medicine. Analysis of the structure of sanitary losses shows that limb injuries account for 55 % to 81.4 %, with about 35 % of them accompanied by bone fractures. …”

Time-dependent scale-free brain dynamics during naturalistic inputs by Philipp Klar, Yasir Çatal, Gerhard Jocham, Robert Langner, Georg Northoff

“…We obtained three key findings: First, the brain’s β(t) showed a distinct temporal structure in visual and auditory regions during naturalistic inputs compared to the resting-state, investigated in the 7 Tesla Human Connectome Project dataset. …”
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Complex mechanical-thermal synthesis of nanostructured calcium hydrosilicates for cement composites by Evgeny A. Shoshin, Denis K. Timokhin, Alexander V. Strakhov, Maria P. Kochergina, Georgy A. Korolkov

“…The use of nanosized calcium hydrosilicates as additives accelerating the structure formation of cement compositions is becoming increasingly popular. …”
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CALPHAD-Assisted Analysis of Fe-Rich Intermetallics and Their Effect on the Mechanical Properties of Al-Fe-Si Sheets via Continuous Casting and Direct Rolling by Longfei Li, Xiaolong Li, Lei Shi, Shouzhi Huang, Cong Xu, Guangxi Lu, Shaokang Guan

“…Notably, Mn addition further refined the grain structure of casting ingots and enhanced the strength of both ingots and rolled sheets. …”
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Genomic architecture of purebred and crossbred Moghani lambs with Texel and Booroola sheep by Reza Talebi, Mohsen Mardi, Mehrshad Zeinalabedini, Tomasz Szmatoła, Mehrbano Kazemi Alamouti, Seyyedeh Azadeh Javadi Taklimi, Mohammad Reza Ghaffari

“…Genotyping-by-sequencing (GBS) was used to assess genetic diversity, admixture patterns, and selection signatures. Structure analysis revealed complex admixture in BMM and BRM, while TDM and TTM were more homogeneous. …”
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Complex Variation in Afrotropical Mammal Communities With Human Impact by Deogratias Tuyisingize, Lars Kulik, Delagnon Assou, Diorne Zausa, Solange Kamga, Onella Mundi, Stefanie Heinicke, Inza Kone, Samedi Jean Pierre Mucyo, Tenekwetche Sop, Christophe Boesch, Colleen Stephens, Anthony Agbor, Samuel Angedakin, Emma Bailey, Mattia Bessone, Charlotte Coupland, Josephine Head, Tobias Deschner, Paula Dieguez, Villard Ebot Egbe, Anne‐Céline Granjon, Thurston Cleveland Hicks, Sorrel Jones, Ammie K. Kalan, Kevin E. Langergraber, Juan Lapuente, Kevin C. Lee, Laura K. Lynn, Nuria Maldonado, Maureen S. McCarthy, Amelia Meier, Lucy Jayne Ormsby, Alex K. Piel, Lilah Sciaky, Volker Sommer, Fiona A. Stewart, Erin G. Wessling, Jane Widness, Roman M. Wittig, Pauline Strohbach, Mimi Arandjelovic, Yntze van derHoek, Hjalmar S. Kühl

“…We assessed variation in the structure and composition of Afrotropical medium and large mammal communities within and outside protected areas, and under varying human impact. …”
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In-silico design and evaluation of quinoline-dione derivatives as Mycobacterium tuberculosis DprE1 inhibitors by Maimuna Shehu Rufa’i, Ibrahim A. Abdulganiyyu, Abduljelil Ajala, Mohnad Abdalla, Reham M. Alahmadi, Maaweya E. Awadalla, Khadija Abdulganiyyu, Asma’u Mahe, Yahaya Sa’id Gwarzo, Nafisatu Kabir

“…This research primarily focusses on the in-silico development of novel 3-Methyl-3 H-naphtho[1,2,3-de]quinoline-2,7-dione derivatives as potential DprE1 inhibitors. Methodology A structure-based drug design strategy was employed to identify robust candidates, incorporating pharmacokinetic analyses, molecular docking, and molecular dynamics (MD) simulations. …”
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Histone Methyltransferases AcDot1 and AcRmtA Are Involved in Growth Regulation, Secondary Metabolism, and Stress Response in <i>Aspergillus carbonarius</i> by Angelo Agnusdei, Adrián González-García, Donato Gerin, Stefania Pollastro, Francesco Faretra, Luis González-Candelas, Ana-Rosa Ballester

“…Histone post-translational modifications (HPTMs) can affect gene expression by rearranging chromatin structure. Between these, histone methylation is one of the most studied in filamentous fungi, and different conserved domains coding for methyltransferase were found in <i>Aspergillus</i> spp. genomes. …”
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Evaluation of Soil Aggregate Sieving: The Impact of Field Moisture Content on Size Distribution and Stability by Jie Liu, Yuping Yang, Jian Zhou, Xintong Feng, Yuan Li, Yuze Li, Junlin Zi, Chunru Wang, Enli Wang, Yuehui Jia

“…Soil aggregation, a critical component of soil structure, is significantly influenced by soil moisture content, which can vary substantially across different field conditions. …”
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Cross-linking of fungal β-glucosidase on Al2O3 nanocrystals synthesized using Cajanus cajan L. Millsp. extracts for in suit genistein manufacture by Sikander Ali, Afra Ejaz, Muhammad Umar Hayyat, Muhammad Usman Ahmad, Zafar Siddique, Baber Ali, Sezai Ercisli, Tabarak Malik, Reem M. Aljowaie, Mohamed Soliman Elshikh, Muhammad Ammar Javed

“…In XRD analysis, peaks depicted the crystalline structure of Al2O3 NCs ranging from 10–50°. The size of NCs was confirmed by using different magnifications (1.01, 2.00, 3.00, 5.00, 7.02, and 10 K X) of SEM images obtained. …”
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Study on Antifungal Mechanism of Lipopeptide Extract from Bacillus amyloliquefaciens Against Alternaria alternata in Tomato by Yingying FAN, Yingying DAI, Yuanyuan ZHANG, Tingting SHEN, Yan WANG, Peicheng WANG, Fengjuan LIU, Cheng WANG

“…【Conclusion】The lipopeptide extract can inhibit the growth of A. alternata by destroying spore and mycelium structure and regulating the expression of key genes.…”
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A technique for separating viable islets of Langerhans from a fragment of human pancreatic tail by A. S. Ponomareva, L. A. Kirsanova, N. V. Baranova, G. N. Bubentsova, I. A. Miloserdov, E. A. Volkova, V. I. Sevastyanov

“…The morphological study of the EP fragments at different times of cold ischemia did not reveal significant differences in the histological presentation of the organ parenchyma; the islet structure appeared intact. Vital staining confirmed the separated IL viability in vitro for at least 1–3 days.Conclusion. …”
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HPDL Variant Type Correlates With Clinical Disease Onset and Severity by Eun Hye Lee, Olivia Kim‐Mcmanus, Jennifer H. Yang, Richard Haas, Maha S. Zaki, Ghada M. H. Abdel‐Salam, Yuji Nakamura, Mohamed S. Abdel‐Hamind, Darius Ebrahimi‐Fakhari, Julian E. Alecu, Nicola Brunetti‐Pierri, Varunvenkat M. Srinivasan, Vykuntaraju K. Gowda, Stephanie Gross, Yasemin Alanay, Paria Najarzadeh Totbati, Manya Yadavilli, Liana Friedman, Naomi Meave Ojeda, Joseph G. Gleeson

“…The biallelic genotypes were classified into truncating/truncating, truncating/missense, and missense/missense variants, mapped onto the predicted 3D protein structure, and correlated with severity. Results Patients with biallelic truncating variants presented with severe phenotypes and earlier ages of onset. …”
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RNA-seq analysis of shrimp tropomyosin-induced allergic reactions through PI3K/Akt pathway by Yanchu Li, Yanchu Li, Yuying Yang, Junyao Li, Rui Guo, Zhiqiang Niu, Weicheng Hu, Shucheng Liu, Shucheng Liu, Shuai Wei, Shuai Wei

“…The results indicated that TM upregulated the expression of phosphorylated PI3K/ Akt and NFκB pathways in Caco-2 cells, further damaged the TJ structure of intestinal epithelial cells and promoted the release of inflammatory factors. …”
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