Tongue-coating microbiota as a predictive biomarker of washed microbiota transplantation efficacy in pediatric autism: integration with clinical features by Hao-Jie Zhong, Zhao-Yu Pan, Yao-Fei Wei, Qian Yu, Lei Wu, Hong Wei, Xing-Xiang He

“…Methods This study investigated the structure and function of the tongue-coating microbiota in children with ASD and explored its correlation with ASD symptoms and gut microbiota. …”
Get full text

LorDist: a novel method for calculating the distance based on functional data analysis with application to longitudinal microbial data by Xinhe Qi, Menghan Zhang, Tongqing Wei, Jinran Lin, Xingming Zhao, Yin Yao, Yueqing Hu, Yan Zheng

“…By explicitly preserving the temporal structure inherent in microbiome data, LorDist enables robust detection of subtle yet critical biological shifts, paving the way for improved diagnostics and personalized therapeutic strategies in microbiome science.…”
Get full text

How Early Could the Milky Way’s Disk Form? by Vadim A. Semenov, Charlie Conroy, Aaron Smith, Ewald Puchwein, Lars Hernquist

“…In our enhanced-physics simulation, the galaxy develops a bistable ISM structure (warm, with T ∼ 10 ^4 K, and cold, with T < 100 K) and exhibits significantly more efficient, early, and bursty star formation than in TNG. …”
Get full text

Optimizing Effects of Organic Farming and Moderately Low Nitrogen Levels on Soil Carbon and Nitrogen Pools by Guanghua Wang, Yu Yang, Yuqi Chen, Shilong Yu, Xiaomin Huang, Min Jiang, Zujian Zhang, Lifen Huang

“…Notably, the organic cultivation mode increased the activities of enzymes involved in the carbon–nitrogen cycle in the cultivated layer and optimized the structure of humus, which gave the proportion of aggregates with a particle size greater than 0.5 mm more advantages. …”
Get full text

Phenotypic Traits, SSR Core Primer Screening, and Genetic Diversity Analysis of Toxicodendron vernicifluum From Different Seed Sources in Yunnan, China by Huiping Zeng, Xingze Li, Jiayu Feng, Cai Wang, Dan Zong, Tao Jiang, Xinglan Wei, Qiong Dong

“…Combining phenotypic traits, we used 24 selected primer pairs to analyze the genetic diversity and genetic structure of all T. vernicifluum samples. The results showed that seeds from the NLS and ZYG populations performed best. …”
Get full text

Gremlin1 repression-mediated mitochondrial network hyperfunction contributes to TCE-induced zebrafish cardiac defects by Huifang Deng, Zhijie Bai, Chaoji Huangfu, Ningning Wang, Miao Chen, Gaofu Li, Congshu Huang, Ting Ao, Xiang Tang, Tiantian Xia, Li Zhang, Pan Shen, Wei Zhou, Yue Gao

“…Consistently, grem1a knockdown in zebrafish induced cardiac phenotypes generally like those of the TCE-treated group, accompanying the disarrangement of myofibril structure. Single-cell RNA-seq depicted that mitochondrial respiration in grem1a-repressed cardiomyocytes was greatly enhanced, ultimately leading to a branch from the normal trajectory of myocardial development. …”
Get full text

Preparation and Application of Chitosan-Essential Oil Nanoemulsion Preservation Pads for Blueberry Preservation by Jieying SHI, Yanping MOU, Zhouxin LU, Jiaxin LU, Lei WANG, Kaiping CONG, Andi SUO, Tingting LI

“…To address postharvest fungal decay in blueberries, this study developed chitosan-based nanoemulsions containing oregano essential oils (OEO) and thyme essential oils (TEO) in varying concentrations via high-speed homogenization. The structure and properties of the nanoemulsion and the preservation pad were characterized by particle size, polydispersity index, embedding rate, loss rate and scanning electron microscopy (SEM). …”
Get full text

Spatiotemporal analysis of economic and ecological water resource resilience and its drivers in the Poyang Lake Basin based on the PSR model by FU Shuai, FENG Yingxiang, YU Jie, XU Bingxian, LI Lanhai, LI Xiuxiang, PENG Yuxin

“…Interactions between per capita GDP, industrial structure, and ecological background were found to have significant impact on system resilience.…”
Get full text

The potential &amp; limitations of monoplotting in cross-view geo-localization conditions by Bradley J. Koskowich, Michael J. Starek, Scott A. King

“…Traditional photogrammetry methods like structure-from-motion (SfM) or simultaneous localization and mapping (SLAM) can technically accomplish CVGL, but require a sufficiently dense collection of camera views in order to recover camera pose. …”
Get full text

Breaking polarization-breakdown strength paradox for ultrahigh energy storage density in NBT-based ceramics by Wenjun Cao, Yanwei Wu, Xiaoyu Yang, Daqin Guan, Xuecen Huang, Feng Li, Youmin Guo, Chunchang Wang, Binghui Ge, Xu Hou, Zhenxiang Cheng

“…Herein, we propose a strategy to overcome the paradox through a unique high-entropy design aimed at regulating phase structure and minimizing interfacial polarization. …”
Get full text

Extracellular matrix-degradable polymer nanostimulants elicit potent immune responses in orthotopic pancreatic cancer via sono-activatable dual-drug synergism by Meng Li, Danling Cheng, Yue Wang, Chongwen Xuan, Viktar Abashkin, Jindong Xia, Ling Ding, Jingchao Li

“…Simultaneously, the generated 1O2 can be cleaved by 1O2-responsive fragments, disrupting the nanoparticle structure and enabling controlled and precise release of the two immune drugs at the tumor site, thus minimizing off-target effects. …”
Get full text

Crude Radix Aconiti Lateralis Preparata (Fuzi) with Glycyrrhiza Reduces Inflammation and Ventricular Remodeling in Mice through the TLR4/NF-κB Pathway by Ping Yan, Wen Mao, Lushuai Jin, Mingsun Fang, Xia Liu, Jiali Lang, Lu Jin, Beibei Cao, Qiyang Shou, Huiying Fu

“…CFZ, CFZ+GC, and PFZ significantly improved left ventricular function and structure and reduced myocardial damage. CFZ+GC was more effective than CFZ and PFZ, whereas CFZ had higher toxicity than CFZ+GC and PFZ. …”
Get full text

Preliminary results of the implementation of the program to reduce morbidity and prevent mortality from diseases of the circulatory system in workers of locomotive crews by E. A. Zhidkova, E. M. Gutor, V. B. Pankova, M. F. Vilk, I. A. Popova, K. G. Gurevich, O. M. Drapkina

“…In 2018, 10476 questionnaires were collected (&gt;7% of employees), and in 2021 — 14403 questionnaires (&gt;10% of employees). The age structure of railways has not changed, which made it possible to analyze the frequency of occurrence of risk factors in dynamics.Results. …”
Get full text

Adsorption potential of CuO-embedded chitosan bead for the removal of acid blue 25 dye by Ismaila Olalekan Saheed, Nuraliah Irdina Zairuddin, Syaza Atikah Nizar, Megat Ahmad Kamal Megat Hanafiah, Ahmad Faiz Abdul Latip, Faiz Bukhari Mohd Suah

“…The micrograph of CS showed a non-porous membranous surface, while CS-CuO shows a relatively rough and irregularly shaped sheet-like structure perforated with pores network. The functional groups O−H, C═O, C−O and N−H on the CS-CuO support its attachment to AB25 dye as reflected in change of absorption signals on FTIR spectra. …”
Get full text

A novel drug prejudice scaffold-imidazopyridine-conjugate can promote cell death in a colorectal cancer model by binding to β-catenin and suppressing the Wnt signaling pathway by Min Hee Yang, Basappa Basappa, Suresha N. Deveshegowda, Akshay Ravish, Arunkumar Mohan, Omantheswara Nagaraja, Mahendra Madegowda, Kanchugarakoppal S. Rangappa, Amudha Deivasigamani, Vijay Pandey, Peter E. Lobie, Kam Man Hui, Gautam Sethi, Kwang Seok Ahn

“…In-depth analysis using structure-based bioinformatics showed that CHL-C strongly binds to β-catenin, with a binding affinity comparable to that of ICG-001, a well-known β-catenin inhibitor. …”
Get full text

Shifts in Fungal Communities and Potential Functions Under Masson Pine Forest-to-Tea Plantation Conversion in Subtropical China by Xiaofang Ma, Xiaofang Ou, Dan Chen, Yong Li, Cameron McMillan, Tida Ge, Ji Liu, Min Xue, Cong Wang, Weijun Shen

“…Herein, a field experiment was conducted in a Masson pine forest (F), a 5-year-old tea plantation without (FT-CK) fertilization or with (FT-N), and a 30-year-old tea plantation (FT-O) to assess the impact of Masson pine forest-to-tea conversion on soil fungal abundance, community structure, and functional guilds by using qPCR and high-throughput sequencing. …”
Get full text

A Bayesian Network Approach to Predicting Severity Status in Nuclear Reactor Accidents with Resilience to Missing Data by Kaiyu Li, Ling Chen, Xinxin Cai, Cai Xu, Yuncheng Lu, Shengfeng Luo, Wenlin Wang, Lizhi Jiang, Guohua Wu

“…With the integration of simulation data and physical knowledge, the BN enables dynamic inference and remains robust under missing-data conditions—common in real-time energy monitoring. Its hierarchical structure organizes variables across layers, capturing initial conditions, intermediate dynamics, and system responses vital to energy safety management. …”
Get full text

Lactobacillus Johnsonii YH1136 alleviates schizophrenia-like behavior in mice: a gut–microbiota–brain axis hypothesis study by Liqin Zheng, Jinge Xin, Huiqian Ye, Ning Sun, Baoxing Gan, Xuemei Gong, Shusheng Bao, Min Xiang, Hesong Wang, Xueqin Ni, Hao Li, Tao Zhang

“…Subsequent 16S rRNA sequencing of intestinal contents suggests that L. johnsonii YH1136 modulates the gut flora structure and composition by increasing the relative abundance of Lactobacillus and decreasing Dubosiella in SCZ mice. …”
Get full text

Research on a machine vision-based electro-killing pheromone-baited intelligent agricultural pest monitoring method by Guozhi Li, Zhengbo Liu, Zhengbo Liu, Zelin Feng, Jun Lyu, Bin Li, Guo Chen, Qing Yao

“…This model incorporates an AKConv module to enhance feature extraction, reducing false detections from limb separation. The CBAM-PANet structure improves detection rates of sticky pests, while the FocalNet module optimizes fine-grained feature capture, excluding non-target pests. …”
Get full text

Deep sequencing of yeast and mouse tRNAs and tRNA fragments using OTTR by Hans Tobias Gustafsson, Lucas Ferguson, Carolina Galan, Tianxiong Yu, Heather Upton, Ebru Kaymak, Zhiping Weng, Kathleen Collins, Oliver J Rando

“…Among the major classes of RNAs in the cell, tRNAs remain the most difficult to characterize via deep sequencing approaches, as tRNA structure and nucleotide modifications can each interfere with cDNA synthesis by commonly used reverse transcriptases (RTs). …”
Get full text