Immersive virtual reality learning environments for higher education: A student acceptance study by Stefan Aufenanger, Jasmin Bastian, Glória Bastos, Maria Castelhano, Célia Dias-Ferreira, Emmanuel Fokides, Damianos Gavalas, Vlasios Kasapakis, Androniki Agelada, Apostolos Kostas, George Koutromanos, Gregory Makrides, Leonel Morgado, Daniela Pedrosa, Tomasz Szemberg, Alivizos Sofos, Justyna Szpond

“…Researchers from Cyprus, Germany, Greece, Poland, and Portugal developed and evaluated five different immersive VRLEs, each focusing on diverse educational topics, including ancient Greek technology, sea urchin measurements, linear algebra, and historical expeditions. The study aims to determine effective instructional design principles for VRLEs and assess students' acceptance and learning outcomes.The VRLEs were designed based on literature-derived principles that emphasise ease of tool usage, authentic experiences, and continuous feedback. …”
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Association between lncRNA H19 and osteoporosis in postmenopausal patients with type 2 diabetes mellitus by Teng Yang, Xiuli Feng, Na Wang, Tongyu Zhang, Zhichen Zheng, Guofeng Wang

“…Additionally, multiple linear regression analysis demonstrated that age, HbA1c, FBG, TGF-β1, and BMD were key determinants of the expression of lncRNA H19. …”
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INFLUENCE OF THE CYP3A4 ISOENZYME METABOLIC ACTIVITY AND CYP2C19 GENE POLYMORPHISMS ON CLOPIDOGREL ANTIPLATELET EFFECT IN PATIENTS WITH ACUTE CORONARY SYNDROME UNDERGOING PERCUTANE... by K. B. Mirzaev, R. E. Kazakov, V. V. Smirnov, D. A. Andreev, D. A. Sychev

“…Clopidogrel laboratory resistance (P2Y12 Reaction Units (PRU)>208) was found out to be higher in the CYP2C19*2-carriers as compared with non-carriers: 53.8% in the patients with the CYP2C19*1/*2 genotype and 16.2% in subjects with the CYP2C19*1/*1 genotype (odds ratio [OR]=1.8; 95% confidence interval [95% CI]: 1.0–3.2; р=0.0067). Linear regression analysis has revealed that smaller mean diameter of stent slightly reduces the risk of clopidogrel resistance development. …”
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Simultaneous Determination of Unbound Plasma Concentration of Methotrexate and 7-Hydroxymethotrexate in Children Patients Receiving High-Dose Methotrexate Therapy by Dong WC, Gao SS, Shi B, Li HR, Jiang Y, Guo JL, Zhang ZQ, Zhang YZ

“…We investigated the connection between unbound and total plasma concentrations of MTX and 7-OH-MTX, as well as how these concentrations relate to liver and renal function.Results: The method that was developed is both simple and accurate. A weak linear relationship was observed between the concentrations of unbound and total 7-OH-MTX (r2 = 0.732). …”
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Kilohertz-Linewidth Brillouin Photonic Crystal Fiber Laser With Non-Resonance Pumping Configuration by Guoqing Ji, Zhiyuan Huang, Wenbin He, Ruochen Yin, Yu Zheng, Xin Jiang, Yuxin Leng, Meng Pang

“…No lasing line of high-order Stokes was observed in experiments as the laser pump power was gradually increased to ∼200 mW, giving a nearly-linear lasing slope.…”
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Correcting Tibiotalar Alignment Correlates with FAO Changes after Total Ankle Replacement by Ricardo Villar MD, Emily Teehan MS, Kira Lu, Ranqing Lan MS, Patricia Friedmann MS, Jensen Henry MD, Constantine Demetracopoulos MD

“…Correlation between changes in TTA and FAO was addressed by Pearson`s correlation test. Linear regression was used to investigate the association between changes in TTA with changes in FAO. …”
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The mediating role of accelerated biological aging in the association between household air pollution from solid cooking fuels and neuropsychiatric disorders by Rui Tang, Haisheng Wu, Ling Jiang, Jie Zhou, Xia Gao, Jiazhen Zheng, Ya-Ping Tang, Mingxi Tang

“…The associations of switching cooking fuels with KDM-BA acceleration (KDM-BAA) and neuropsychiatric diseases were elucidated by generalized linear models and Cox proportional hazard models, respectively. …”
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Phthalate exposure is associated with subclinical coronary atherosclerosis: The Aragon Workers' Health Study (AWHS) by Diana María Mérida, Carolina Torrijo-Belanche, Belén Moreno-Franco, Martín Laclaustra, Jimena Rey-García, Sofía Gimeno-Ruiz, Ana Bayán-Bravo, Pilar Guallar-Castillón

“…A 1-unit increase in the natural logarithm of MEP was associated with a 21 % higher prevalence of SCA (OR: 1.21; 95 % CI: 1.02–1.44), showing a linear relationship. Positive but non-significant associations were observed for MiBP and MnBP. …”
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Clinical and immunological biomarkers can identify proliferative changes and predict renal flares in lupus nephritis by Marta Calatroni, Emanuele Conte, Matteo Stella, Federica De Liso, Francesco Reggiani, Gabriella Moroni

“…Methods For histological class prediction, we evaluated the immunological tests performed on the day of kidney biopsy by linear and multiple regression analyses. For flare prediction, univariable and multivariable Cox analyses were made at baseline, 6, and 12 months. …”
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Platelet reactivity clinical and biochemical markers when taking acetylsalicylic acid as part of dual antiplatelet therapy in the myocardial infarction subacute period by T. P. Pronko, V. A. Snezhitskiy, A. V. Kapytski

“…Parameters influencing the ASPItest value according to univariate linear regression analysis: body mass index (β=0.53, 95% CI: 0.11-0.96; p=0.013); waist circumference (β=0.31, 95% CI: 0.14-0.49; p=0.0004); erythrocyte sedimentation rate (β=0.27, 95% CI: 0.12-0.42; p=0.0004); white blood cells count (β=1.47, 95% CI: 0.51-2.42; p=0.0027); platelets count (β=0.042, 95% CI: 0.019-0.064; p=0.00025); thrombocrit (β=36.8, 95% CI: 14.6-59.1; p=0.0012); mean platelet volume (β=1.94, 95% CI: 0.06-3.84; p=0.043); platelet distribution width (β=1.36, 95% CI: 0.22-2.51; p=0.02); creatinine (β=0.11, 95% CI: 0.011-0.21; p=0.03); C-reactive protein (β=0.18, 95% CI: 0.05-0.32; p=0.007); TRAP-test (β=0.18, 95% CI: 0.11-0.24; p=0.000001); fibrinogen (β=2.6, 95% CI: 1.17-4.02; p=0.0004). …”
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Development and Validation of a Hydrophilic Interaction Liquid Chromatography Tandem Mass Spectrometry Method for the Determination of Asparagine in Human Serum by Haoyang Lu, Xiaoyun Zeng, Lihua Yu, Zhanzhang Wang, Danna Lin, Xiaojia Ni, Dewei Shang, Ming Zhang, Jinqing Hu, Shuhua Deng, Xiuqing Zhu, Yuqing Chen, Huanshan Xie, Lihua Yang, Yuguan Wen

“…Serum ASN concentrations were determined over a linear calibration curve range of 2–200 μM, with acceptable accuracies and precisions. …”
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Prognostic significance of FT3 levels in hypertrophic cardiomyopathy patients with HFpEF by Zhen-Yu Yang, Zhi-Yuan Zhang, Wei-Jie Zhang, Da Liu, Fu-Shi Piao, Xiangyu Yan, Fang-Tao Shi, Min Yang, Jing Chen, Sheng-song Zhu, Hong-Hou He, Pei-Hong Wu, Cheng Qian, Min Lin, Jun-Qing Feng, Chun-jin Lai

“…Patients with lower FT3 exhibited poorer long-term outcomes, with RCS identifying a critical threshold of 2.885 pg/ml (P-non-linear < 0.05).ConclusionsFT3 is a robust prognostic marker in HCM-HFpEF patients, supporting its integration into risk stratification. …”
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Non‐invasive lung cancer diagnosis by detection of GATA6 and NKX2‐1 isoforms in exhaled breath condensate by Aditi Mehta, Julio Cordero, Stephanie Dobersch, Addi J Romero‐Olmedo, Rajkumar Savai, Johannes Bodner, Cho‐Ming Chao, Ludger Fink, Ernesto Guzmán‐Díaz, Indrabahadur Singh, Gergana Dobreva, Ulf R Rapp, Stefan Günther, Olga N Ilinskaya, Saverio Bellusci, Reinhard H Dammann, Thomas Braun, Werner Seeger, Stefan Gattenlöhner, Achim Tresch, Andreas Günther, Guillermo Barreto

“…The Em/Ad expression ratios of GATA6 and NKX2‐1 detected in EBCs were combined using linear kernel support vector machines (SVM) into the LC score, which can be used for LC detection. …”
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Integrating quantitative traits and growth hormone gene polymorphism in Indonesian crossbred chickens for genetic improvement and marker-assisted selection by Depison Depison, Gushairiyanto Gushairiyanto, Ratna Sholatia Harahap, Raden Abdul Muthalib, Abdul Azis, Yun Alwi, Sarwo Edy Wibowo

“…Data were analyzed through a one-way analysis of variance and General Linear Models to determine phenotypic and genotypic associations. …”
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Evaluación del potencial de mejoramiento genético en el crecimiento en altura de Acacia mangium Willd. Evaluation of the breeding potential in height growth for Acacia mangium Will... by Iván Javier Pastrana-Vargas, Miguel Espítia-Camacho, Olman Murillo-Gamboa

“…The prediction of genetic parameters individual and of families was conducted by the method BLUP (best linear unbiased prediction) and the variance components by REML (restricted maximum likelihood) procedure using the software SELEGEN. …”
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Preseason neuromuscular versus endurance training leads to greater improvements in isokinetic strength, muscle damage, and inflammation parameters in highly trained female soccer p... by Ali Belamjahad, Claire Tourny, Anthony C. Hackney, Nidhal Jebabli, Naoual Chariba, Fatiha Laziri, Ayoub Saeidi, Ismail Laher, Urs Granacher, Hassane Zouhal

“…NMT included strength, power, linear sprint and change-of-direction speed, and dynamic stability exercises. …”
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Advanced lung cancer inflammation index and its predictive value for all-cause and cardiovascular mortality among osteoarthritis patients: a NHANES-based study from 2001 to 2018 by Guiyou Wu, Guiyou Wu, Dongqiang Gu, Dongqiang Gu, Haigang Jia, Haigang Jia, Lei Hong, Lei Hong, Xishun Wang

“…These methodological strategies ensured comprehensive exploration of the ALI-mortality link in OA patients while minimizing bias and enhancing generalizability.ResultsThis research delved into the health records of 2,133 individuals, revealing a notable connection: those with OA and higher ALI scores exhibited significantly lower rates of both overall and CVD-related fatalities. Specifically, a non-linear relationship characterized by an L-shaped curve was observed, indicating that ALI scores below a critical threshold (inflection point at 61.18) were associated with progressively elevated mortality risks, while scores above this threshold exhibited a protective effect against mortality. …”
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Association between atherogenic index of plasma and all-cause mortality and cardiovascular disease among individuals with non-alcoholic fatty liver disease or metabolic dysfunction... by Jialu Lv, Jiangnan Yao, Leyi Zheng, Jiaxin Shao, Jijie Jin, Qianrong Zheng, Jiayi Teng, Jianghua Zhou, Fuman Cai, Pan Huang, Xuepei Jiang

“…The findings suggested a linear association between the AIP index and the risk of CVD in participants with NAFLD or MASLD. …”
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Characterization of external cross-talk from silicon photomultipliers in a liquid xenon detector by D. Gallacher, A. de St. Croix, S. Bron, B. M. Rebeiro, T. McElroy, S. Al Kharusi, T. Brunner, C. Chambers, B. Chana, Z. Charlesworth, E. Egan, M. Francesconi, L. Galli, P. Giampa, D. Goeldi, S. Lavoie, J. Lefebvre, X. Li, C. Malbrunot, P. Margetak, N. Massacret, S. C. Nowicki, H. Rasiwala, K. Raymond, F. Retière, S. Rottoo, L. Rudolph, X. Shang, M. A. Tétrault, T. Totev, S. Viel, N. V. H. Viet

“…The relative increase in intensity of SiPM ExCT emission between 4 and 5 V is consistent with expectation for the linear increase of gain with respect to overvoltage.…”
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Performance and comparison of FLCCheck: a novel serum free light chain assay for the Auxiliary Diagnosis of Multiple Myeloma by Jinghao Cao, Xi Chen, Yu Zhou, Yajuan Lu, Aoli Deng, Sainan Li, Yuhan Chen, Jing Du, Jun Xia

“…Results The FLCCheck assay demonstrated a validated linear range, high precision, and strong resistance to interference for both κ and λ light chain detection. …”
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