Age-Related Increases in PDE11A4 Protein Expression Trigger Liquid–Liquid Phase Separation (LLPS) of the Enzyme That Can Be Reversed by PDE11A4 Small Molecule Inhibitors by Elvis Amurrio, Janvi H. Patel, Marie Danaher, Madison Goodwin, Porschderek Kargbo, Eliska Klimentova, Sonia Lin, Michy P. Kelly

“…Interestingly, age-related increases in PDE11A4 protein ectopically accumulate in spherical clusters that group together in the brain to form linear filamentous patterns termed “PDE11A4 ghost axons”. …”
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Low-Carbohydrate Diet Patterns That Favor High-Quality Carbohydrates Are Associated with Beneficial Long-Term Changes in Biomarkers of Inflammation and Oxidative Stress in the Fram... by Ghaida F Aloraini, Nicola M McKeown, Gail T Rogers, Sai Krupa Das, Alice H Lichtenstein, Paul F Jacques

“…Least-square mean change in the inflammation and oxidative stress score across quintile categories of LCDS was estimated using multivariable linear regression models, adjusted for potential confounders. …”
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Neuroanatomical mapping of huntingtin-associated protein 1 across the rostral and caudal clusters of mouse raphe nuclei and its immunohistochemical relationships with serotonin by Marya Afrin, Marya Afrin, Md Nabiul Islam, Mirza Mienur Meher, Mirza Mienur Meher, Mir Rubayet Jahan, Kanako Nozaki, Koh-hei Masumoto, Akie Yanai, Koh Shinoda, Koh Shinoda

“…Our results indicated that in the rostral cluster, HAP1-ir cells were extensively distributed across the caudal linear raphe, median raphe, dorsal raphe, supralemniscal raphe, caudal part of the dorsal raphe, pre-pontine and pontine raphe nuclei. …”
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Snow cover setting-up dates in the north of Eurasia: relations and feedback to the macro-scale atmospheric circulation by V. V. Popova, A. V. Shiryaeva, P. A. Morozova

“…In the same time negative linear correlation revealed between snow extent and AO index changes during 1950–2008 from statistically insignificant values (in 1950–70 and 1996–2008) to coefficient values –0.82 ÷ –0.85 in 1973–1994 (Fig. 4, а, б). …”
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Determining mosquito age using surface-enhanced Raman spectroscopy and artificial neural networks: insights into the influence of origin and sex by Zili Gao, Yuzhen Zhang, Laura C. Harrington, Courtney C. Murdock, Elisabeth Martin, Dalton Manbeck-Mosig, Steve Vetrone, Nicolas Tremblay, Christopher M. Barker, John M. Clark, Lili He, Wei Zhu

“…The ANNs utilized a multilayer perceptron with two hidden layers of 100 neurons and rectified linear unit (ReLU) activation. Classification tasks used cross-entropy loss; regression applied mean squared error. …”
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THE ECONOMIC TRANSFORMATION: THE ROLE OF SUSTAINABLE BANKING IN QUALITY GROWTH by PULBERE (GHELASE) CARMEN CORNELIA, NECULITA MIHAELA

“…Missing data points were estimated using linear interpolation and extrapolation to predict future values. …”
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Impact of health literacy and primary language on the decision to pursue trial of labor after prior cesarean delivery by Daisy Leon-Martinez, Christine Dehlendorf, Molly Zeme, W. John Boscardin, Anjali J. Kaimal, William A. Grobman, Miriam Kuppermann

“…Decision quality was assessed by calculating mean scores for decision-quality scales and using linear regression to estimate adjusted mean differences (aMD) by health literacy and NEPL. …”
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Correlation between ore mineralogical composition at different depths and Bond Work Index for the Erdenetiin Ovoo Cu-Mo porphyry deposit, Mongolia by Batmunkh Tumen-Ayush, Chinzorig Bavuu, Narangerel Adiyasuren, Davaajargal Darambazar, Ganbileg Davaajav, Khaliun Amartuvshin, Sondor Ganbat, Tsend-Ayush Tserendagva, Altankhuyag Dorjyunden, Ganzorig Chimed

“…An equation-based approach to the Bond Work Index estimation model demonstrates a strong linear correlation (R²=0.895) with the measured Bond Work Index from experimental tests, with the highest Bond Work Index measured at 19.06 kWh/t. …”
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Inverse Association of Longitudinal Variations in Fat Tissue Radiodensity and Area by Giulia Besutti, Marta Ottone, Efrem Bonelli, Simone Canovi, Roberto Farì, Francesco Farioli, Annarita Pecchi, Guido Ligabue, Massimo Pellegrini, Pierpaolo Pattacini, Paolo Giorgi Rossi

“…The associations between each compartment area and radiodensity variations (standardized values) were evaluated in univariate linear models and models adjusted by age and sex. …”
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Association between circulatory immune cell to high-density lipoprotein cholesterol ratios and testosterone level in adult men: findings from NHANES 2011–2016 by Yangyang Mei, Bo Zhang, Yiming Chen, Renfang Xu, Dong Xue, Qianfeng Zhuang, Xingliang Feng

“…In the fully adjusted models, log-transformed NHR, PHR, MHR, and LHR were all linearly negatively associated with total testosterone levels and linearly positively associated with the risk of TD. …”
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Strong Association of Waist Circumference (WC), Body Mass Index (BMI), Waist-to-Height Ratio (WHtR), and Waist-to-Hip Ratio (WHR) with Diabetes: A Population-Based Cross-Sectional... by Fu-Liang Zhang, Jia-Xin Ren, Peng Zhang, Hang Jin, Yang Qu, Yao Yu, Zhen-Ni Guo, Yi Yang

“…The median of each quartile was used for a linear trend test. Results. For all four body fat-measuring indices of body mass index (adjusted OR: 3.300, 95% CI: 2.370, 4.595), WC (adjusted OR: 5.131, 95% CI: 3.433, 7.669), WHR (adjusted OR: 3.327, 95% CI: 2.386, 4.638), and WHtR (adjusted OR: 5.959, 95% CI: 3.922, 9.054), patients in the highest quartile were more likely to have diabetes than those in the lowest quartile. …”
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Stress reactivity during short trauma narratives in adolescents with post-traumatic stress disorder (PTSD) and complex PTSD by Oswald D. Kothgassner, Sarah Macura, Andreas Goreis, Diana Klinger, Bettina Pfeffer, Sofia M. Oehlke, Karin Prillinger, Johanna X. Kafka, Heidi Elisabeth Zesch, Anna Felnhofer, Paul L. Plener

“…However, understanding the differences in physiological stress reactivity and negative cognitive-emotional patterns between adolescents with PTSD and C-PTSD remains a notable research gap.Objective: This study examined group differences in autonomic nervous system (ANS) reactivity during the sharing of a short trauma narrative, including resting and recovery phases, and compared subjective experiences of stress, shame, and guilt among adolescents with PTSD, C-PTSD, and trauma-exposed controls.Methods: In a repeated-measures design, 52 adolescents (14–18 years) with PTSD (n = 17), C-PTSD (n = 18), and a control group (n = 17) were assessed for heart rate, heart rate variability, and subjective experiences of stress, shame, and guilt during a standardized trauma interview, as well as during baseline and recovery phases.Results: Linear mixed-effects models revealed a significant interaction between group and time point (F = 4.134, p < .001). …”
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Paracentesis complication rates and use of ultrasound: impact of a point-of-care ultrasound training course in the veterans affairs healthcare system by Robert Nathanson, Rahul Khosla, Rebecca Theophanous, Zahir Basrai, Abdulkareem A. Agunbiade, Christopher Schott, Jeremy Boyd, Michael J. Mader, Kevin J. Murray, Jacqueline A. Pugh, Erin P. Finley, Nilam J. Soni

“…Rates of paracentesis performed in non-radiology settings with and without ultrasound guidance and procedural complications were collected from the VA corporate data warehouse (CPT and ICD-10 procedure and diagnosis codes) and pre- and post-course surveys of course participants. A best fit linear regression line was established for quarterly rates of each group and the y-intercept and slope of each line was compared. …”
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Radiofrequency Performance Analysis of Metal-Insulator-Graphene Diodes by Leslie Paulina Cruz-Rodríguez, Mari Carmen Pardo, Anibal Pacheco-Sanchez, Eloy Ramírez-García, Francisco G. Ruiz, Francisco Pasadas

“…Additionally, the diode demonstrated a non-linearity of 6.64 at 0.7 V and an asymmetry of 806.6 in a bias window of ±1 V, which resulted in a competitive value compared to other state-of-the-art rectifying technologies. …”
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Sedimentación de partículas con distribución de tamaño fractal Sedimentation of fractal size distribution particles by Roberto R. Filgueira, Yakov A. Pachepsky, Lidia L. Fournier, Mirta G. García, Guillermo O. Sarli

“…The agreement between the model and the experimental data, using non linear regression, was excellent. Resulting fractal fragmentation dimensions ranged from 2.404 to 2.512, for samples from La Plata, Argentina, and between 2.434 and 2.819 for soils from California, USA. …”
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VMMCD: VMamba-Based Multi-Scale Feature Guiding Fusion Network for Remote Sensing Change Detection by Zhong Chen, Hanruo Chen, Junsong Leng, Xiaolei Zhang, Qi Gao, Weiyu Dong

“…By leveraging VMamba’s global modeling ability with linear computational complexity, the computational resources needed for extracting global features are reduced. …”
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Prediction Equations for Calculating Maximal Inspiratory Pressure from Spirometry and Thoracic Ultrasound After COVID-19 with Gastroesophageal Reflux Disease in Indonesian Adults... by Siti Chandra Widjanantie, Ari Fahrial Syam, Nury Nusdwinuringtyas, Agus Dwi Susanto, Rudy Hidayat, Aria Kekalih, Maria Regina Rachmawati, Maryastuti Maryastuti, Triya Damayanti, Putri Prathiwi, Won Ah Choi, Seong Woong Kang

“…The data were analyzed using Pearson correlational analysis and multiple linear regression. Results: Sixty-two participants were recruited: mean age 37.23 ± 9.76 years and average MIP 49.85 ± 18.13 cmH2O. …”
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Impact of black carbon exposure on length of hospital stay in asthma patients: a retrospective cohort study in yulin, China by Yu Chen, Qian Huang, Huimeng Liu, Baosen Meng, Can Zhang, Xiaohui Li, Chunlai Yang, Mengchun Wang, Peiying Yang, Li Cheng, Baibing Mi, Yu Zheng

“…Daily PM2.5 components concentrations (BC, Organic Matter, Sulfates, Nitrates, Ammonium) were derived from 10-km resolution CMAQ model data. General linear models (GLM) and restricted cubic spline (RCS) assessed exposure-response relationships across lag0-lag10, stratified by age groups and seasons. …”
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Prognostic value of triglyceride-glucose index combined with stress hyperglycemia ratio for all-cause mortality in critically ill patients with stroke by Tengli Li, Zhiheng Yi, Yangshen Huang, Yuhan Tan, Shan Gao, Tingting Wang, Shaowei Guo

“…RCS analysis confirmed linear positive correlations between the TyG index, SHR, and mortality at all time points (all P for non-linearity > 0.05). …”
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Plasmodium falciparum merozoite surface protein 2 genetic polymorphism and multiplicity of infection in selected malarious areas of Northwest Ethiopia by Agenagnew Ashagre, Jimma Dinsa Deressa, Daniel Abebe Mekonnen, Melat Abdu, Tegegne Eshetu, Migbaru Keffale, Aberham Abere, Mulugeta Aemero Tegegne

“…The merozoite surface protein 2 allele frequency and multiplicity of infection were computed. Linear regression was employed to evaluate the associations between the multiplicity of infection, parasite density, and age by calculating Spearman’s rank correlation coefficients. …”
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