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78342
NFIA-dependent upregulation of SMC4 promotes metastasis and metabolic reprogramming in glioma
Published 2025-08-01“…BackgroundGliomas, particularly glioblastoma, are aggressive brain tumors with poor prognosis and unmet therapeutic needs. Structural maintenance of chromosomes 4 (SMC4), a core component of the condensin complex, is dysregulated in multiple cancers, but its role in glioma metabolism and metastasis remains unclear.MethodsUsing integrated multi-omics analyses of glioma datasets, we assessed SMC4 expression and its correlation with clinical outcomes. …”
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78343
Evaluating of Four Irrigation Depths on Soil Moisture and Temperature, and Seed Cotton Yield Under Film-Mulched Drip Irrigation in Northwest China
Published 2025-07-01“…Soil temperature at the flowering and boll setting stage negatively affected seed cotton yield and was inversely correlated with soil water storage. The structural equation model (SEM) further indicated that both soil water storage and soil temperature primarily influenced seed cotton yield boll weight rather than boll number. …”
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78344
BIOMECHANICAL STUDY OF SINGLE ROOTED TEETH RESTORED WITH DOWEL CORS
Published 2018-03-01“…When restoring the coronal portion of premolar using dowel core maximum values of the equivalent stresses in all structural components of the examined bone tissue does not exceed the corresponding values of ultimate strength, the presence and design of the dowel core significantly affect the values of the equivalent stresses in the dentin of the tooth root, and has almost no effect on stresses in the periodontal and bone tissues of the lower jaw; the localization of the fields of maximum values of equivalent stress on the surface of the root portion of the dentin in the tooth a healthy load corresponds to the location and the value of the equivalent stress tooth under load which restores; the most unfavourable loading is the combined effect of the vertical component of the functional load and the horizontal component, targeted in vestibular- lingual direction. …”
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78345
Epileptic manifestations, cognitive impairment and autism spectrum disorders in patients with agenesis of the corpus callosum: the results of neuropsychological testing
Published 2019-03-01“…In brain MRI scans of all patients of Group I, ACC was combined with various congenital development defects; in 3 (25%) patients of Group II, the structural lesions were dominated by congenital (hemispheric, arachnoid) cysts.Conclusion. …”
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78346
Dose effects of ultraviolet and terahertz laser radiation on the plasma membrane of erythrocytes
Published 2025-08-01“…The objective was to study the biogenic activity of ultraviolet (UV) and terahertz (THz) ranges of LLLR on the structural and functional state of red blood cells of rats in vitro. …”
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78347
The mediating role of psychological distress in the association between migration experiences and stigma and coping strategies: a cross-sectional study on Ethiopian migrant returne...
Published 2024-11-01“…Psychological distress was measured using the 21- item version of the Depression, Anxiety and Stress Scale and coping strategies were measured with the Brief-COPE. Structural equation modeling was employed to estimate the relationship among variables. …”
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78348
Exploring the roles of self-determined motivation and perceived organizational support in organizational change
Published 2025-04-01“…The partial least squares-structural equation modelling (PLS-SEM) technique and SPSS PROCESS (model 14) were utilized to analyze the data. …”
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78349
Integrative genomic analysis and diagnostic modeling of osteoporosis: unraveling the interplay of autophagy, osteogenesis, adipogenesis, and immune infiltration
Published 2025-04-01“…BackgroundOsteoporosis (OP), marked by reduced bone density and structural decay, poses a heightened risk of fractures. …”
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78350
Modulating physical properties of ASnF3 (A = K, Rb) perovskites under pressure: Insights for enhanced optoelectronic performance via first-principles
Published 2025-09-01“…The Goldschmidt tolerance factor, formation energy, and Born stability criteria are used to verify the structural, thermodynamic, and mechanical stabilities, respectively. …”
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78351
Integrative habitat analysis and multi-instance deep learning for predictive model of PD-1/PD-L1 immunotherapy efficacy in NSCLC patients: a dual-center retrospective study
Published 2025-07-01“…Notably, peritumoral structural features emerged as significant predictors of treatment efficacy. …”
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78352
Effects of age at first separation from parents on suicidal ideation, suicide planning and suicide attempts among left-behind children: the causal mediating effect of traumatic eve...
Published 2025-07-01“…Causal mediation analysis (structural equation modelling) was used to evaluate the mediating effect of TEs, and bootstrap resampling was employed to assess the robustness of the causal mediation analysis.Results A total of 12 162 (6269 LBC) participants were included in this study; the prevalence rates of SI, SP and SA among LBC were 30.7%, 18.6% and 11.9%; and LBC had a higher risk of SI (OR: 1.32), SP (OR: 1.40) and SA (OR: 1.25) than non-LBC, all p<0.001. …”
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78353
Egységtörekvések a magyar lutheránus és kálvinista egyházban a 19. század első felében
Published 2015-12-01“…During the Synods of Buda and Pest in 1791 attempts have been made to establish structural links between the two churches. Starting with the 1840’s years the two churches were nearing each other in the field of schools and education. …”
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78354
Biventricular electromechanical dysfunction and molecular remodeling in a rat model of advanced pulmonary arterial hypertension
Published 2025-07-01“…Conclusions Our findings revealed that both ventricles showed structural remodeling but only the RV underwent electromechanical alteration, while the LV displayed metabolic and inflammatory alteration. …”
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78355
Immunoinformatic-driven design and evaluation of multi-epitope mRNA vaccine targeting HIV-1 gp120
Published 2025-05-01“…Their comprehensive computational findings, including physicochemical, structural, and 3D refinement analyses, substantiated the stability and quality of the translated vaccine. …”
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78356
Inequity in the transmission of malaria infection among children and adolescents: a cohort study in rural Guinea
Published 2025-08-01“…These findings highlight the need for targeted, equity-sensitive interventions that address structural vulnerabilities and seasonal dynamics to reduce the malaria burden and promote health equity.…”
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78357
Norbert Elias i les paradoxes educatives actuals Norbert Elias y las paradojas educativas actuales Norbert Elias and current educational paradoxes
Published 2011-09-01“…The authors believe that this perspective, which seeks never to lose sight of the profound inter-relationship between social and personal, structural and psychological elements, might be of use in dealing with some of the tensions which currently exist both in the education system as such and in education in general (families, leisure, sport and so on) and how they relate to one another. …”
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78358
Transcriptome and Anthocyanin Profile Analysis Reveals That Exogenous Ethylene Regulates Anthocyanin Biosynthesis in Grape Berries
Published 2025-07-01“…Transcriptomics analysis showed that there were a total of 825 and 1399 differentially expressed genes (DEGs) 12 h and 24 h after treatment. Moreover, key structural genes in the anthocyanin synthesis pathway were strongly induced, including <i>VvPAL</i>, <i>VvCHS</i>, <i>VvF3H</i>, <i>VvF3′5′H</i>, <i>VvDFR</i> and <i>VvUFGT</i>. …”
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78359
TRIM24 regulates chromatin remodeling and calcium dynamics in cardiomyocytes
Published 2025-07-01“…However, its precise role in cardiomyocytes remains unclear. Using molecular, structural and functional approaches, this study investigates the impact of TRIM24 on cardiomyocyte function and gene regulation. …”
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78360
The mediating role of self-compassion in the relationship between childhood trauma and the symptoms of body dysmorphic disorder
Published 2025-07-01“…Methods A cross-sectional design employing structural equation modeling (SEM) was utilized to construct an optimal model for BDD symptoms, where the mediating role of self-compassion was tested in the relationship between childhood trauma and BDD symptoms. …”
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