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78021
Validation of the American-Spanish Oxford Cognitive Screen (OCS-Sp): Normative data and psychometric properties in acute stroke patients
Published 2025-06-01“…Results: Following a linear regression model demonstrating age, gender, and particularly years of education affecting the performance of the OCS-Sp, the cut-off scores obtained for all subtests were adjusted by these demographic variables. …”
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78022
Q221K mutation in VP2 drives antigenic shift of infectious bursal disease virus
Published 2025-07-01“…Neutralization assays revealed that mAb 5B5 could inhibit replication of an engineered attIBDV carrying 221K in Leghorn male hepatoma (LMH) cells. Structural analysis further found that 221K is surface-exposed and alters local electrostatic potential, possibly facilitating immune evasion.DiscussionAll these demonstrated that 221K is a unique antigenic site in VP2 of nVarIBDV associated with immune escape, providing novel insights into the antigenicity of nVarIBDV and novel targets for efficient diagnostics, vaccine design, and molecular surveillance of IBDV.…”
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78023
Genomic analysis and lysogenic conversion of novel RAP44-like phages in Riemerella anatipestifer
Published 2025-08-01“…Genomic analysis revealed high similarity to the first characterized Riemerella phage, RAP44, particularly in structural gene modules. Lysogens exhibited resistance to superinfection by prophages, similar to the reference strain ATCC 11845. …”
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78024
Tracing the evolutionary trajectory of the IncP-2 plasmid co-harboring blaIMP-45 and blaVIM-1: an outbreak of Pseudomonas aeruginosa co-producing IMP-45 and VIM-1 carbapenemases in...
Published 2025-06-01“…Conjugation experiments were conducted to assess the conjugative potential of the IncP-2 plasmid co-harboring blaVIM-1 and blaIMP-45. Structural and molecular docking studies explored the PBP3 (P527S) mutation’s role in aztreonam resistance.ResultsFrom February 2022 to July 2024, 17 ST313 VIM-1-IMP-45 CRPA strains from 10 transplant patients were identified. …”
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78025
Experiences of support to return to work after stroke: longitudinal case studies from RETAKE trial
Published 2025-03-01“…Objectives This article aims to understand participants’ experiences of being supported to return to work and explores the social and structural factors which support, or act as barriers to, implementation of the Early Stroke Specialist Vocational Rehabilitation intervention. …”
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78026
The mediating role of attitude and environmental awareness in the influence of green advertising and eco-labels on green purchasing behaviors
Published 2025-06-01“…The convergent and discriminant validity of the research model was verified through confirmatory factor analysis and structural equation modeling. SPSS 20 and AMOS 24 were used for statistical analyses. …”
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78027
Effect of grinding wheel type and cooling method on grinding quality of SiCf/SiC ceramic matrix composites
Published 2025-04-01“…ObjectivesSiCf/SiC fiber-reinforced ceramic matrix composites have been widely used in aerospace, nuclear energy, and high temperature structural parts due to their excellent high-temperature resistance, high specific strength, and oxidation resistance. …”
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78028
Tricin selectively combats KRAS-mutant non-small cell lung cancer by inhibiting the PDGF-BB-induced SRC/MAPK/AP-1/PD-L1 signaling pathway and potentiating the antitumor effect of a...
Published 2025-06-01“…Currently, the identification of effective therapies for KRAS-mutant NSCLC is difficult for reasons of the structural and biochemical characteristics of the KRAS protein. …”
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78029
SEPLINE: Socioeconomic Position in Epidemiological Research—A National Guideline on Danish Registry Data
Published 2025-07-01“…Insights from these workshops were integrated into iterative refinements of the guideline.Conclusions and Implications: The guideline provides a structured framework for conducting socioeconomic epidemiological research using Danish registry data, offering specific information on data sources and recommendations about variable selection, measurement timing, and data handling. …”
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78030
Home Occupant Archetypes
Published 2019-11-01“…Parallelly, in-depth and semi-structured interviews were conducted, which are techniques used to gather qualitative behavioural data from the home occupants. …”
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78031
The Effectiveness of Emotion-Focused Therapy on Pain Anxiety and Resilience in Patients with Migraine
Published 2024-08-01“…., 2020). EFT, with its structured and phase-oriented approach, helps patients modify their emotional responses to pain by focusing on core emotional experiences and unmet attachment needs, enabling them to develop more adaptive coping strategies. …”
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78032
Classification of GBA1 variants and their impact on Parkinson’s disease: an in silico score analysis
Published 2025-08-01“…Here, we classified GBA1 missense variants using predictive and structural scores, and analysed their associations with enzyme activity, Saposin C (SapC) interaction and PD progression in 639 patients with heterozygous GBA1 variants from five cohorts. …”
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78033
Advancing dementia care: a review of Italy’s public health response within the WHO Global Action Plan and European strategies
Published 2025-08-01“…This study analyses IFAD activities from 2021 to 2023, offering insights into Italy’s public health response to dementia and its relevance to global strategies.Methods We conducted a structured, iterative review of all activities coordinated by the Italian Dementia Observatory (OssDem-Istituto Superiore di Sanità (ISS)) within IFAD 2021–2023. …”
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78034
Genotype-Phenotype Correlations in Denys-Drash Syndrome in Children
Published 2025-04-01“…Introduction: Denys-Drash syndrome (DDS) is a rare disease typically associated with a triad of early onset nephrotic syndromes (NS), susceptibility to Wilms tumor (WT), and genitourinary structural defects. DDS is caused by Wilms’ tumor suppression gene (WT1) variants, with the most frequent variants in exons 8 and 9. …”
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78035
The Impact of Conservative Accounting on the Speed of Leverage Adjustment in Response to Stock Price Crash Risk
Published 2025-03-01“…Dynamic trade-off theory further posits that companies seek to optimize their capital structures, with transaction costs playing a pivotal role in determining the speed of adjustment. …”
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78036
Direito e marxismo: a política de qualificação para trabalhadores desempregados na experiência do MTD em João Pessoa / Law and marxism: the qualification policy for unemployed work...
Published 2012-12-01“…With theorist basis on Marxist references that deal with educational formation and social/economic development the contradiction conditioned by the market structure is analysed. This structure allowed the lifesaving acceptance of a policy that is actually a form of domination towards the workers. …”
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78037
Quantification of Subsurface Hydrological Connectivity Using Wavelet Coherence Analysis
Published 2025-01-01“…While quantitative methods for subsurface structural connectivity have been developed, characterizing subsurface process connectivity remains a major challenge in hillslope hydrology research. …”
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78038
SHARD: an improved method for staining and visualizing multiplex immunofluorescence in optically cleared postmortem human brain tissue
Published 2024-10-01“…These 3D images allow for the analysis of large regions of interest and can be used to study structural and spatial changes that occur during neurodegeneration. …”
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78039
A computational DNA methylation method to remove contaminated DNA from spent embryo culture medium for noninvasive preimplantation genetic testingResearch in context
Published 2025-04-01“…At the heart of ART success is preimplantation genetic testing (PGT), which enables the detection of chromosomal anomalies, single-gene disorders, and structural rearrangements, enhancing embryo selection and mitigating genetic risk. …”
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78040
The relationship between prenatal perfluorine and polyfluoroalkyl substances (PFAS) exposure and infant neurodevelopment: Modifying effects of DHA revised
Published 2025-09-01“…Infant neurodevelopment was assessed at 6 and 12 months using the Ages and Stages Questionnaire (ASQ-3) score. Generalised linear models (GLMs) and Bayesian kernel machine regression (BKMR) were used to evaluate the associations between single or mixed PFAS exposure and infant neurodevelopment. …”
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