Serum titin/creatinine ratio as a biomarker for discriminating disease severity in Duchenne and Becker muscular dystrophies by Yoshinori Nambu, Kayo Osawa, Taku Shirakawa, Aiko Sunami, Shoko Sonehara, Ryosuke Bo, Kandai Nozu, Masafumi Matsuo, Hiroyuki Awano

“…Among potential biomarkers, the levels of the fragmented products of titin, a structural muscle protein, may directly reflect the degree of muscle loss in DMD and BMD. …”
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Identification and Analysis of MHCⅡ Genes in Wuzhishan Pigs by LIU Yuanyuan, XIN Wenshui, CHAO Zhe, CAO Zongxi, CAI Yifei, LI Qiang, LI Lingwei, LIU Guangliang

“…Bioinformatics tools were employed to analyze the physicochemical properties, phylogenetic relationships, conserved motifs, structural domains, chromosomal localization, and syntenic relationships of these genes.ResultsEight MHCⅡ genes were identified in Wuzhishan pigs, designated as SLA-DRA, SLA-DQA, SLA-DQB, SLA-DRB, SLA-DOB, SLA-DMB, SLA-DMA and SLA-DOA. …”
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Parental Phasing Study Identified Lineage-Specific Variants Associated with Gene Expression and Epigenetic Modifications in European–Chinese Hybrid Pigs by Chenyu Li, Mei Ge, Keren Long, Ziyin Han, Jing Li, Mingzhou Li, Zhiyan Zhang

“…In this study, we established three crossbred pig families derived from distant genetic lineages and systematically identified variants from different lineages, including single nucleotide polymorphisms (SNPs) and structural variations (SVs). At the phase level, we quantitatively analyzed gene expression, four histone modifications (H3K4me3, H3K27ac, H3K4me1, and H3K27me3), and the binding strength of transcription factor (CTCF) in backfat (BF) and longissimus dorsi (LD) muscle. …”
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Enhancing the performance of lead-free CsInCl3 perovskite solar cells with Ag and Au plasmonic nanoparticles: A DFT and SCAPS-1D analysis by Muhammad Zulqarnain Abbasi, Anees Ur Rehman, Muhammad Sheraz, Wajahat Ullah Khan Tareen, Muhammad Kaleem, Shayan Tariq Jan, Haider Ali, Teong Chee Chuah

“…We carefully examined the electronic, optoelectronic, and structural properties of doped CsInCl3 using first-principles Density Functional Theory (DFT) calculations and SCAPS-1D simulations. …”
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Histologic and ultrastructural degeneration of rotator cuff tendons in elderly patients with glenohumeral arthritis and cuff tear arthropathy by Daisuke Mori, Azuma Kagaku, Ke Yong Wang, Takuya Tokunaga, Yoshikazu Kida, Yoshiharu Shimozono, Homare Nishiyama, Kazuha Kizaki, Noboru Funakoshi, Fumiharu Yamashita, Masahiko Kobayashi

“…Conclusions Our histologic and structural results showed that rotator cuff tendons in elderly OA patients without RC tears had relatively high mean Bonar scores, indicating degenerative change of the tendon, which was comparable to the degree of tendon degeneration in elderly CTA patients. …”
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Function of a novel human gene TOX promoting cell proliferation by DENG Weiwei, LI Jing, GAO Peng, HAO Dongxia, ZHANG Lu, SHI Taiping, WANG Ying

“…Bioinformatics analysis was used to identify structural characteristics of TOX, and RT-PCR (reverse transcription PCR) was used to detect its expression in cell lines. …”
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Analysis of mitochondrial-targeted antioxidant SkQ1 effectiveness on myocardial ischemia-reperfusion injury in a rat model: Focus on morphological and ultrastructural tissue study by E. A. Senokosova, E. A. Velikanova, R. A. Mukhamadiyarov, O. D. Sidorova, E. O. Krivkina, L. V. Antonova, E. V. Grigoriev

“…Cytochrome C was distributed evenly.Conclusion. 12 ng/mL of SkQ1 demonstrates pronounced antioxidant effects in the ischemic myocardium leading to a higher degree preservation of the heart muscle compared to 120 ng/mL of SkQ1 that was associated with an aggravated oxidative stress and structural changes of the tissue.…”
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Efficacy and mechanism of action of harmine derivative H-2-104 against Echinococcus granulosus infection in mice by Huijing Gao, Qinwei Xu, Jiang Zhu, Kadierya Kuerban, Bei Chen, Jun Zhao, Kalibixiati Aimulajiang, Liang Teng

“…H-2-104, a derivative of HM obtained through structural modification of its parent nucleus, represents a promising candidate for further investigation. …”
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Development of an electrocardiographic prediction model for outflow tract idiopathic premature ventricular contraction with decreased left ventricular ejection fraction by Pinliang Liao, Xiaolian Cai, Wen Zhang, Min Ou, Heling Ren, Maoqin Shu

“…Even in the absence of any underlying heart disease, isolated ventricular premature contractions (IPVCs) can still lead to cardiac structural remodeling and impaired heart function during long-term follow-up. …”
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MANAGEMENT OF ANGINA ATTACKS IN HEART FAILURE DUE TO NONCORONARY HEART DISEASE: TRIMETAZIDINE USAGE by M. Yu. Sitnikova, T. A. Lelyavina, V. L. Galenko

“…To study trimetazidine (TZ) impact on the frequency of hospitalizations, structural and functional myocardium parameters, exercise tolerance (ET) in congestive heart failure patients (CHF) of nonischemic etiology (after myocarditis or DCMP), having complaints on chest pains.Material and methods. …”
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E-cigarette use and susceptibility among Indonesian youth: the role of social environment, social media, and individual factors by Mouhamad Bigwanto, Melinda Pénzes, Nurul Kodriati, Emma Rachmawati, Nida Amalia, Róbert Urbán

“…Methods A school-based online survey of 1,600 Indonesian youth aged 15–24, conducted from March to August 2023 in Jakarta, Yogyakarta and East Kalimantan, assessed e-cigarette use, susceptibility, and predictors, including social environment, SM marketing exposure, and sensation-seeking behavior. Structural equation modeling and multinomial regression were used to analyze associations. …”
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Essential histidine residues in Bombyx mori nucleopolyhedrovirus GP64 mediate pH-dependent membrane fusion by Haijue Tian, Kai Chen, Xinyu Li, Ying Xu, Bifang Hao, Jinshan Huang

“…The identification of critical pH-sensing residues in BmNPV GP64 lays a foundation for future structural studies and understanding pH-dependent activation in other enveloped viruses.…”
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The “Silent Enemy” Called Renal Artery Stenosis: A Mini-Review by José Silva, Juan Tonheiro, Fernanda Rodrigues

“…FMD tends to create structural abnormalities of the artery, whereas atherosclerosis causes plaque formation and endothelial dysfunction of the artery. …”
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Neural-induced human adipose tissue-derived stem cell secretome exerts neuroprotection against rotenone-induced Parkinson’s disease in rats by Mahesh Ramalingam, Sujeong Jang, Jinsu Hwang, Hyong-Ho Cho, Byeong C. Kim, Han-Seong Jeong

“…Secretome treatment could reverse the ROT-induced damages in the neuronal structural and functional proteins, mitochondrial apoptosis, and caspase cascade. …”
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Phospholipase Cζ, the Molecular Spark of Fertilization and Male Infertility: Insights from Bench to Bedside by Aris Kaltsas, Maria-Anna Kyrgiafini, Zissis Mamuris, Fotios Dimitriadis, Athanasios Zachariou, Michael Chrisofos, Nikolaos Sofikitis

“…A narrative review was conducted to examine the molecular architecture and biochemical features of PLCζ, with particular emphasis on how its distinctive structural domains facilitate the hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP₂) and the induction of calcium (Ca²⁺) oscillations in the oocyte. …”
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Stress enhances expression of calcium‐binding proteins and NMDAR subunit genes in the rat hippocampus by Aravind Parthasarathy, Ramesha Hanumanthappa, Sarojini R. Bulbule, Kiran P.C., Hemalatha Nanjaiah, Gopinath G., Siddaiah B.M., David Muniswamy, Devaraju Kuramkote Shivanna

“…Expression of calcium‐binding protein genes in the hippocampus, antioxidant assays, structural alterations in hippocampal neurons, and depressive‐like behavior were determined. …”
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Antimicrobial resistance in a protracted war setting: a review of the literature from Palestine by Ramya Kumar, Osama Tanous, David Mills, Bram Wispelwey, Yara Asi, Weeam Hammoudeh, Omar Dewachi

“…Notably, most studies attributed AMR to local practices, often overlooking broader structural and socio-political drivers. This review underscores the need to contextualize AMR within the environment, particularly under conditions of sustained warfare.IMPORTANCEThis study goes beyond merely reviewing and summarizing data on AMR in the occupied Palestinian territories (oPt), a region enduring chronic war-like conditions. …”
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Systematic analysis of the antibacterial mechanisms of reuterin using the E. coli Keio collection by Jinyan Li, Teng Wang, Xi Yang, Yuhan Duan, Hirotada Mori

“…Furthermore, the deletion of biofilm-related genes (omrA and aaeR) was found to increase biofilm formation, which functions as a structural barrier, reducing the uptake of environmental drugs into the cells and contributing to resistance against reuterin. …”
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The impact of man-made virtual reality: from impressions to a person's worldview / Воздействие техногенной виртуальной реальности: от впечатлений к мировоззрению личности... by Olga Moskvitina / Ольга Александровна Москвитина

“…Possible distortions of the main aspects of a person's worldview are given: substantive, value, structural and functional in nature. As conditions for the occurrence of these distortions, the originality of the impressions received from the impact of TVR and the peculiarities of the work of the brain are put forward. …”
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A Brief Engagement Intervention Adapted for Racial and Ethnic Minority Young Adults in Mental Health Services: Protocol for a Pilot Optimization Trial by Kiara L Moore, Aaron H Rodwin, Marya Gwadz, Doris F Chang, Linda M Collins, Michelle R Munson

“…Emerging research suggests developmentally tailored interventions that enable personalized exploration of cultural and structural contexts; encourage trust in relationships with service providers; enhance hope for recovery; and increase self-efficacy to adhere to treatment can improve engagement among underserved REM young adults with mental health disorders. …”
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