Racial and Ethnic Disparities in Diabetes Prevention Outcomes: Insights from the Prediabetes Informed Decisions and Education Study by Yelba Castellon-Lopez, O. Kenrik Duru, Norman Turk, Gerardo Moreno, Keith C. Norris, Amanda Vu, Rintu P. Saju, Chi-Hong Tseng, Kia Skrine-Jeffers, Carol M. Mangione, Dominick Frosch, Tannaz Moin

“…We stratified the outcomes by race and ethnicity using a generalized linear mixed-effects model. Results: The study participants (n = 515) had an average age of 56 years (standard deviation [SD] = 11.0), hemoglobin A1c of 6.0% (SD = 0.20), and body mass index of 30.3 (SD = 5.2). …”
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A combined nutritional index and mortality in patients with peritoneal dialysis by Wenjun Lin, Juan Wu, Xiaojiang Zhan, Yueqiang Wen, Xiaoyang Wang, Xiaoran Feng, Fenfen Peng, Na Tian, Ning Su, Qingdong Xu, Niansong Wang, Xiangwei Liao, Xianfeng Wu

“…Cause-specific hazard models examined the association between TC/BA and mortality.Results Of 2907 patients, 754 (25.9%) patients died, including 351 (46.6%) deaths due to cardiovascular disease. A positive linear relationship was observed between TC/BA and all-cause mortality (nonlinear, p = 0.374). …”
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The gut microbiota features and the application value in predicting recurrent risks for gallstone patients who underwent laparoscopic cholecystectomy by Huiqiang Li, Weili Li, Xinzheng Liu, Jianhua Zhang, Chuncheng Lin, Shushen Ji, Huihui Jiang, Tao Wang, Zijian Su

“…The Chao1 index of the recurrent group was remarkably lower than the control group (P < 0.05). Linear discriminant analysis (LDA) effect size (LEfSe) analysis showed that Phocaeicola dorei (LDA score = 4.2, P < 0.05) was the feature microbiota in the recurrent group. …”
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First-in-human phase 1 study of the ICOS agonist feladilimab on patients with advanced solid tumors by David Turner, Antoine Italiano, Victor Moreno, Steven Hirschfeld, Juan Martin-Liberal, Michele Maio, Todd M Bauer, Christophe Le Tourneau, Danny Rischin, Catherine Ellis, Eric Angevin, Aaron Hansen, Helen Zhou, Ivan Diaz-Padilla, Frans Opdam, Sapna Yadavilli, Marc Ballas

“…Accumulation ratio ranged from 1.4 to 2.5 and was generally consistent with expected patterns of accumulation for a monoclonal antibody, and the drug showed linear dose proportionality. ICOS receptor occupancy was maximal at doses&gt;0.1 mg/kg. …”
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COMPARATIVE CHARACTERISTICS OF CLASSICAL AND EVERSION ENDARTERECTOMY OF THE CAROTID ARTERIES by I. P. Dudanov, B. C. Abuazab, V. V. Akhmetov

“…In patients who underwent eversion CE, in the early postoperative period, a significant decrease in the asymmetry coefficient was revealed in the study of background LSC valuesdue to an increase in the blood flow velocity in the ipsilateral middle cerebral artery (MCA) and a decrease in the linear velocity of the blood flow (LVBF) in the posterior cerebral artery (PCA) on the side of the initially stenotic ICA on the background of improvement of hemodynamic conditions in all cases (p &lt; 0.05). …”
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Vitamin D Levels in Pre-frail Older Adults and Its Correlation with Hand Grip Strength by Noto Dwimartutie, Siti Setiati, Tirza Z Tamin, Ani Retno Prijanti, Alida R Harahap, Dyah Purnamasari, Kuntjoro Harimurti, I Dewa Putu Pramantara

“…Correlations between vitamin D levels and hand grip strength were evaluated by Spearman’s rank correlation coefficient. Multiple linear regression analysis was carried out to assess contribution of variables that influence hand grip strength. …”
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Impact of outpatient palliative care on healthcare costs in Germany – an analysis of cancer and non-cancer patients based on health insurance data by Melissa Hemmerling, Sabrina Schütte, Sveja Eberhard, Katharina van Baal, Stephanie Stiel, Jona Theodor Stahmeyer

“…The data were analysed descriptively and linear regression models were conducted. Results The descriptive results showed in the group of all individuals, patients receiving outpatient PC had higher costs in all healthcare sectors compared to those who did not receive outpatient PC. …”
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Sex-Dependent Effects of Body Fat on Cardiac Function and Outcomes in Community-Dwelling Older Adults by Haowen Jiang, MBBS, Jie Jun Wong, MBBS, Glades H.M. Tan, BEng, Louis L.Y. Teo, MBBS, See Hooi Ewe, MBBS, PhD, Ru-San Tan, MBBS, Fei Gao, PhD, Angela S. Koh, MBBS, MPH, PhD

“…Correlations between baseline or interval changes (Δ) of WHR, BFM and PBF with follow-up or Δ values of outcomes were analyzed, with multivariable linear regression model adjustments for significant variables. …”
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Autonomic Nervous Regulation was Associated with Sleep Quality Among Peritoneal Dialysis Patients by Huang B, Qian Y, Gao Y, Chen Z, Zhang L, Mao H, Xing C, Ren H, Wang J

“…Serum creatinine (1157.0± 294.3 vs 969.6± 353.4 mmHg, p = 0.022) and phosphorus levels (2.1± 0.5 vs 1.7± 0.5 mmHg, p = 0.002) were higher in the poor sleep quality group compared to the good group. Linear regression analyses indicated that PSQI scores were associated with SKNA (β, − 2.54; 95% CI, − 4.90 to − 0.19; P=0.035), standard deviation of all sinus RR intervals (SDNN) (β, − 0.05; 95% CI, − 0.09 to − 0.01; P=0.015), and SD2 (β, − 0.04; 95% CI, − 0.07 to − 0.01; P=0.018).Conclusion: Poor sleep quality in PD patients may be associated with longer dialysis vintage, higher BMI, higher diastolic blood pressure, and higher level of serum uremic toxin, and affected by cardiac autonomic nerve function disorder.Keywords: peritoneal dialysis, end-stage kidney disease, skin sympathetic nerve activity, heart rate variability, autonomic nervous system, sleep quality…”
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The Relationship between Retinol-Binding Protein 4 and Markers of Inflammation and Thrombogenesis in Children with Kawasaki Disease by Maoling Yang, Haobo Weng, Qiongfei Pei, Fengchuan Jing, Qijian Yi

“…RBP4 had positive correlation with time point of intravenous immunoglobulin (IVIG), Hb, and percentage of leukomonocytes (L%) and negative correlation with the percentage of neutrophils (N%), MPV, C-reactive protein (CRP), neutrophil-to-lymphocyte ratio (NLR), prothrombin time (PT), fibrinogen (Fbg), and D-dimer (DD) in the KD group; RBP4 had positive correlation with the time point of IVIG and L% and negative correlation with N%, MPV, and NLR in the KD-NCALs group; and RBP4 had positive correlation with Hb and L% and negative correlation with N%, CRP, NLR, and PT in the KD-CALs group (p<0.05). Multiple linear regression analysis confirmed that Hb and CRP in the KD group, MPV and N% in the KD-NCALs group, and PT and CRP in the KD-CALs group were independent predictors of RBP4 (p<0.05). …”
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Impella 5.5 use in women: A multicenter study by Michaela Asher, MPhil, David Rekhtman, MD, Amit Iyengar, MD, MSE, John DePaolo, MD, PhD, Cindy Song, MD, Iris Feng, MD, Emma Morganroth, BS, Gabriel Dardik, MD, Max Shin, MD, Noah Weingarten, MD, Alyson Brown, BS, Joyce Wald, DO, Mauer Biscotti, MD, Koji Takeda, MD, PhD, Marisa Cevasco, MD, MPH

“…Laboratory values were examined with a linear mixed model, and a parsimonious multivariable logistic regression was developed to assess factors predictive of in-hospital mortality. …”
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Green One-Step Synthesis and Characterization of Fluorescent Carbon Quantum Dots from PET Waste as a Dual-Mode Sensing Probe for Pd(II), Ciprofloxacin, and Fluoxetine via Fluoresce... by Christian Ebere Enyoh, Qingyue Wang, Weiqian Wang, Miho Suzuki, Go Masuda, Daisuke Nakajima, Senlin Lu

“…The method exhibited linear detection ranges of 1–10 mg/L for Pd²⁺, 50–150 µg/L for CIP, and 100–400 ng/L for FLX, with corresponding limits of detection (LOD) of 1.26 mg/L, 3.3 µg/L, and 134 ng/L, respectively. …”
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A virtual coastal band-driven optimization-based bathymetric approach (VOBA) for optically shallow water with multispectral imagery by Yongming Liu, Shilin Tang, Bin Cao, Zhantang Xu, Xulong Liu, Kai Zeng, Yuye Huang, Wendi Zheng

“…This limitation restricts the accuracy of optimization-based bathymetric approaches, which can estimate water depth without in situ bathymetric data. Therefore, a simple linear relationship was established using in situ reflectance data of optically shallow waters from four different sites in China to derive a virtual coastal band (~445 nm) of Landsat-8 from the adjacent blue band. …”
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Electrochemical determination of paracetamol and chlorpheniramine  using AuNPs-rGO modified glassy carbon electrode by Huynh Van Chung, Nguyen Hai Phong, Dao Thi Cam Minh, Ho Xuan Anh Vu, Pham Khac Lieu, Nguyen Thi Thanh Huyen, Trinh Ngoc Dat, Doan Manh Dung, Do Thi Duyen, Dinh Quang Khieu

“…Under suitable experimental conditions, the SQW-ASV method using AuNPs-rGO-GCE showed a wide linear range from 23.7 µM to 140 µM for PAR and from 7.5 µM to 54 µM for CPM. …”
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Effect of graft sizing in valve-sparing aortic root replacement for bicuspid aortic valve: The Goldilocks ratioCentral MessagePerspective by Perry S. Choi, MD, Amit Sharir, BA, Yoshikazu Ono, MD, Masafumi Shibata, MD, Alexander D. Kaiser, PhD, Yuanjia Zhu, MD, PhD, Alison L. Marsden, PhD, Y. Joseph Woo, MD, Michael R. Ma, MD, Joon Bum Kim, MD, PhD

“…Outcomes included transvalvular gradient, regurgitation fraction, and orifice area. Linear mixed effects model and pairwise comparisons were employed to compare outcomes across groups. …”
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Associations between perceived stress profiles, social connection and work engagement in clinical registered nurses: a mediation analysis and generalized additive models by Yuan Liao, Miaochun Huang, Zhimin Gu, Chun Li, Yan Yu, Qimei Zhang, Xiangyu Lai, Jialin Liu, Kang He, Huiyun Chu, Yao Zhao, Xinyu Wu, Lihua Wu, Yu Li, Sujuan Fang

“…Results (1) The analysis revealed heterogeneity in stress levels among nurses, resulting in the identification of three distinct groups: low stress-high self-demand group (23.4%), high tension-low out-of-control group (57.5%), and high stress-low efficiency group (18.2%). (2) Clinical registered nurses that obtained support from their families were more inclined to be placed in the Low stress-high self-demand group. (3) Social connection significantly mediated the relationship between nurses’ work engagement and perceived stress. (4) Work engagement demonstrated a non-linear relationship with both perceived stress and social connection. …”
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Analysis of the Digestion Dynamics and Dietary Risk Assessment of Fluridone in Cotton Fields via QuEChERS Coupled with HPLC by Sen Wang, Ruitong Yang, Yuxuan Li, Zhiqiang Jin, Yutian Xia, Yipin Zhao, Xiaoqiang Han, Guoqiang Zhang, Chunjuan Wang, Ting Ma, Cailan Wu, Desong Yang

“…The results showed that in a certain concentration range, the concentration and peak area of fluridone showed a good linear relationship (R² > 0.99), with limit of detection (LOD) and limit of quantification (LOQ) values of 0.00090–0.00108 mg·kg⁻¹ and 0.0030–0.0033 mg·kg⁻¹, respectively. …”
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A novel method to predict the haemoglobin concentration after kidney transplantation based on machine learning: prediction model establishment and method optimization by Songping He, Xiangxi Li, Fangyu Peng, Jiazhi Liao, Xia Lu, Hui Guo, Xin Tan, Yanyan Chen

“…Finally, five kinds of machine learning methods, random forest, extreme gradient boosting, light gradient boosting machine, linear support vector classifier and support vector machine, were used to establish classification prediction models, and error-correcting output codes were used to optimize each model. …”
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Efficacy and dose–response relationships of antidepressants in the acute treatment of major depressive disorders: a systematic review and network meta-analysis by Shuzhe Zhou, Pei Li, Xiaozhen Lyu, Xuefeng Lai, Zuoxiang Liu, Junwen Zhou, Fengqi Liu, Yiming Tao, Meng Zhang, Xin Yu, Jingwei Tian, Feng Sun, Jing Ni

“…Moreover, amitriptyline, clomipramine, and reboxetine showed a linear increase in effect size from low to high doses. …”
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Athletic Shoulder Test Differences Exist Bilaterally in Healthy Pitchers by Aaron Trunt, Brandon T. Fisher, Lisa N. MacFadden

“…Bilateral differences in passive ROM, isokinetic, and isometric shoulder strength were examined using paired t-tests while linear relationships between isometric shoulder strength and fastball velocity were assessed using Pearson correlations…”
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