Computation strategies and clinical applications in neoantigen discovery towards precision cancer immunotherapy by Zhenchang Wang, Yu Gu, Xiao Sun, Hao Huang

“…Abstract Neoantigens, which are tumor-specific peptides generated by malignant cells, can be presented to T cells to elicit immune responses. Owing to their tumor-specific properties, neoantigens have emerged as one of the most promising biomarkers and targets for cancer immunotherapy. …”
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Takotsubo Cardiomyopathy: Patients Characteristics, Mortality, and Clinical Significance of Left Ventricular Outflow Tract Gradient, Retrospective Study by Yunis Daralammouri, Hamza Hamayel, Dina Abugaber, Sari Nabulsi

“…A total of 59 patients diagnosed with TC were reviewed during hospitalization, and 40 patients were followed up after discharge by phone contact and cardiology clinic. Most patients were female (91.5%), and nonsignificant coronary artery disease was present in 16.9% of patients. …”
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Macrozoobenthos communities in the area of marine pipeline route at Piltun-Astokhskoye oil field (shelf of northeastern Sakhalin) and their long-term variability by Ludmila S. Belan, Tatyana A. Belan, Alexander V. Moshchenko

“…Cumaceans and amphipod crustaceans are the most numerous groups; sea-urchins, bivalves and cumaceans have the highest biomass. …”
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High-intensity focused ultrasonic ablation of breast cancer by L. I. Moskvicheva

“…At present, for the treatment of this pathology, the methods of the organ-preserving surgical manual allowing to achieve the maximum cosme c eff ect along with the observance of the principles of cancer safety are ge  ng more and more developed,. …”
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CONSERVATION OF DIVERSITY OF LOCAL FRUIT AND WILD BERRY CULTIVARS IN THE ISSYK-KUL REGION OF KYRGYZSTAN by G. E. Sariyeva, M. K. Turdieva, Zh. T. Aitbaeva, S. K. Kadyrkulova, Sh. K. Kachekova, A. K. Kudaibergenova

“…The Issyk-Kul region is one of the most preferable for horticulture regions of Kyrgyzstan. …”
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A Hybrid CNN-LSTM Approach for Muscle Artifact Removal from EEG Using Additional EMG Signal Recording by Marcin Kołodziej, Marcin Jurczak, Andrzej Majkowski, Andrzej Rysz, Bartosz Świderski

“…Although numerous algorithms have been proposed, most rely solely on EEG data. In this study, we introduce a novel approach utilizing a hybrid convolutional neural network–long short-term memory (CNN-LSTM) architecture alongside simultaneous recording of facial and neck EMG signals. …”
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Decoding the Interplay Between Tidal Notch Geometry and Sea‐Level Variability During the Last Interglacial (Marine Isotope Stage 5e) High Stand by N. Georgiou, P. Stocchi, E. Casella, A. Rovere

“…We use a numerical model of cliff erosion embedded within a Monte Carlo simulation to investigate the most likely sea‐level scenarios responsible for shaping one of the best‐preserved tidal notches of Last Interglacial age in Sardinia, Italy. …”
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Evaluating the prognostic value of microbial communities in predicting recurrence of laryngeal carcinoma: a multicenter case-control study by Chi-Yao Hsueh, Xiaohui Yuan, Huiying Huang, Yujie Shen, Qiang Huang, Weida Dong, Danhui Li, Hui-Ching Lau, Xinhui Mao, Simin Liang, Lei Tao, Ming Zhang, Ji Sun, Hongli Gong

“…Abstract Laryngeal squamous cell carcinoma (LSCC) presents significant treatment challenges, especially regarding recurrence after larynx-preservation therapy. …”
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Mechanisms Associated with Mitophagy and Ferroptosis in Cerebral Ischemia-reperfusion Injury by Yugang Ma, Xuebin Wang, Yahui Li, Jing Zhao, Xue Zhou, Xingchen Wang

“…Vascular recanalization by intravenous thrombolysis and mechanical thrombolysis remain the most significant and effective methods for relief of ischemia. …”
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New insights from the application of ZooMS to Late Pleistocene fauna from Grotta di Castelcivita, southern Italy by Annette Oertle, Jacopo Crezzini, Adriana Moroni, Annamaria Ronchitelli, Stefano Benazzi, Armando Falcucci, Giulia Marciani, Matteo Rossini, Ivan Martini, Simona Arrighi, Tom Higham, Francesco Boschin, Katerina Douka

“…The unexpectedly high level of collagen preservation in the bones from the cave confirms the potential for further applications of biomolecular approaches to Pleistocene bones from southern Italy.…”
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Application of Machine Learning in Fault Detection And Classification in Power Transmission Lines by Michel Evariste Tshodi, Nathanael Kasoro, Freddy Keredjim, ALbert Ntumba Nkongolo, Jean-Jacques Katshitshi Matondo, Paul Mbuyi Balowe, Laurent Kitoko

“…The detection and classification of faults facilitates the delivery of superior quality of service, the preservation of the environment, the prevention of equipment damage, and the satisfaction of electricity line subscribers. …”
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Inhibitory Activity and Transcriptional Mechanism of PostbioYDFF against Pseudomonas aeruginosa by Yuqian LIU, Ming WANG, Wei YUAN, Jinhong ZANG, Jinshan ZHAO, Zhaojie LI, Ruiyan HU, Chuantao PENG

“…In the present study, the antibacterial activity of postbiotics PostbioYDFF against Pseudomonas aeruginosa (P. aeruginosa) and its mechanism of action were examined by analyzing its effects on biofilm formation and changes in the ultrastructure and transcriptome. …”
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Cell death signaling and immune regulation: new perspectives on targeted therapy for sepsis by Huang Wu, Jiale Cui, Jie Huang, Yuqi Feng, Jiaxin Zhao, Yalin Zhu, Xiaoming Deng, Xinyu Li, Wangzheqi Zhang, Changli Wang

“…Abstract Cell death is essential for the preservation of tissue homeostasis, regulating inflammatory responses, and shaping immune status. …”
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Left trisectionectomy combined with resection of the right hepatic vein and inferior vena cava after right hepatic vein embolization for advanced intrahepatic cholangiocarcinoma by Toshihiro Suzuki, Tomoki Ebata, Yukihiro Yokoyama, Takashi Mizuno, Tsuyoshi Igami, Junpei Yamaguchi, Shunsuke Onoe, Nobuyuki Watanabe, Masato Nagino

“…Portal vein embolization of the left and right anterior portal veins was performed. As the IRHV was present but thin, RHV was also embolized. Left hepatic trisectionectomy with resection of the involved IVC and RHV, preserving the IRHV, was done. …”
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Expanding cryospheric landform inventories – quantitative approaches for underestimated periglacial block- and talus slopes in the Dry Andes of Argentina by Tamara Köhler, Anna Schoch-Baumann, Rainer Bell, Johannes Buckel, Diana Agostina Ortiz, Dario Trombotto Liaudat, Lothar Schrott

“…In the periglacial belt around 30°S, these areas are often covered by extensive block- and talus slopes, whose distribution and potential permafrost content have received little attention so far. We present the first geomorphological mapping and predictive modeling of these underestimated landforms in a semi-arid high Andean catchment with representative cryospheric landform cover (30°S, 69°W). …”
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SUPRAORBITAL KEYHOLE CRANIOTOMY IN SURGERY OF INTRA- AND EXTRA-AXIAL BRAIN TUMORS by R. S. Dzhindzhikhadze, O. N. Dreval, V. A. Lazarev, A. Kh. Bekyashev, Sh. M. Sadikov, A. V. Polyakov

“…Priority objectives of surgical neurooncology (diagnosis verification, tumor cytoreduction, and preservation of patient’s functional status) can be achieved both through traditional neurosurgical approaches and through the use of keyhole surgery. …”
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Maintaining quality of life in multiple sclerosis: fact, fiction, or limited reality? Mantendo a qualidade de vida na esclerose múltipla: fato, ficção ou realidade circunscrita? by Alina Gomide Vasconcelos, Vitor Geraldi Haase, Eduardo de Paula Lima, Marco Aurélio Lana-Peixoto

“…Preservation of HRQOL levels against certain levels of disability may be restricted to a group of patients.…”
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MORPHOLOGICAL SUBSTANTIATION OF APPLICATION OF THE DEVELOPED STOMATOLOGIC MEDICAL PREPARATION BY THE BIOLOGICAL METHOD OF TREATINMENT OF THE PULPITIS by V. A. Ivashchenko, A. A. Adamchik, V. V. Tairov

“…In the course of the experimental study we detected the activation of reactive and compensatory processes in the tooth pulp tissue with the preservation of its viability by using the developed dental therapeutic preparation and the Biodentin as a comparison preparation on the 30th day of the experiment. …”
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Academic and Socioсultural Adaptation of Students in Russian Universities by P. A. Ambarova, G. E. Zborovsky, V. S. Nikolskiy, N. V. Shabrova

“…The article presents the results of the All-Russian sociological study of academic and sociocultural adaptation of students in Russian universities. …”
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Amphibians and Reptiles Exhibit Different Ecological and Evolutionary Spatial Patterns in the Amazon Basin by Jhon Jairo López‐Rojas, Diego Henrique Santiago, Mirco Solé, Ricardo Lourenço‐de‐Moraes

“…The findings align with the cradle‐museum hypothesis, suggesting that some regions serve as centers of ongoing diversification, others preserve ancient lineages, or serve as both. The cradle‐museum hypothesis should be carefully analyzed, as each taxon presents a distinct pattern. …”
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