Biomimetic Scaffolds Regulating the Iron Homeostasis for Remolding Infected Osteogenic Microenvironment

Biomimetic Scaffolds Regulating the Iron Homeostasis for Remolding Infected Osteogenic Microenvironment

Abstract The treatment of infected bone defects (IBDs) needs simultaneous elimination of infection and acceleration of bone regeneration. One mechanism that hinders the regeneration of IBDs is the iron competition between pathogens and host cells, leading to an iron deficient microenvironment that i...

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Main Authors: Mengting Yin, Zhiqing Liu, Zhongyi Sun, Xinyu Qu, Ziyan Chen, Yuying Diao, Yuxuan Cheng, Sisi Shen, Xiansong Wang, Zhuyun Cai, Bingqiang Lu, Shuo Tan, Yan Wang, Xinyu Zhao, Feng Chen
Format: Article
Language:English
Published: Wiley 2024-11-01
Series:Advanced Science
Subjects:
3D printing
antibacterial activity
bone repair
in situ growth
iron homeostasis
Online Access:https://doi.org/10.1002/advs.202407251
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