Investigating the association between diabetes and carpal tunnel syndrome: A systematic review and meta-analysis approach.

<h4>Introduction</h4>In recent years, several studies have reported on the relationship between diabetes and carpal tunnel syndrome (CTS). However, due to their contradictory results, a systematic review and meta-analysis were conducted to investigate this subject.<h4>Methods</h...

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Main Authors: Elaheh Sanjari, Hadi Raeisi Shahraki, Lusine G Khachatryan, Abdollah Mohammadian-Hafshejani
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0299442&type=printable
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author Elaheh Sanjari
Hadi Raeisi Shahraki
Lusine G Khachatryan
Abdollah Mohammadian-Hafshejani
author_facet Elaheh Sanjari
Hadi Raeisi Shahraki
Lusine G Khachatryan
Abdollah Mohammadian-Hafshejani
author_sort Elaheh Sanjari
collection DOAJ
description <h4>Introduction</h4>In recent years, several studies have reported on the relationship between diabetes and carpal tunnel syndrome (CTS). However, due to their contradictory results, a systematic review and meta-analysis were conducted to investigate this subject.<h4>Methods</h4>This study is a systematic review and meta-analysis of studies published in ISI Web of Science, Scopus, PubMed, Cochrane, Google Scholar, and Embase databases. Heterogeneity in the studies included in the meta-analysis was evaluated using statistical tests such as the Chi-square test, I2, and forest plots. Publication bias was assessed using Begg's and Egger's tests.<h4>Results</h4>This investigation analyzed data from 42 studies conducted between 1985 and 2022, with a total of 3,377,816 participants. The meta-analysis demonstrated that the odds ratio (OR) of CTS in participants with a history of diabetes compared to those without was 1.90 (95% CI: 1.64-2.21; P-value < 0.001). Given that publication bias was observed in this study (Begg's test P-value = 0.01), the modified OR was calculated with consideration of missed studies, which was 1.68 (95% CI: 1.45-1.94; P-value < 0.001).<h4>Conclusion</h4>The results of this study suggest that diabetic patients have 90% higher odds of developing CTS compared to non-diabetic individuals, which is statistically significant.
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spelling doaj-art-ffb084376cca49ad9904fd3f0e3f952d2024-12-10T05:32:53ZengPublic Library of Science (PLoS)PLoS ONE1932-62032024-01-01194e029944210.1371/journal.pone.0299442Investigating the association between diabetes and carpal tunnel syndrome: A systematic review and meta-analysis approach.Elaheh SanjariHadi Raeisi ShahrakiLusine G KhachatryanAbdollah Mohammadian-Hafshejani<h4>Introduction</h4>In recent years, several studies have reported on the relationship between diabetes and carpal tunnel syndrome (CTS). However, due to their contradictory results, a systematic review and meta-analysis were conducted to investigate this subject.<h4>Methods</h4>This study is a systematic review and meta-analysis of studies published in ISI Web of Science, Scopus, PubMed, Cochrane, Google Scholar, and Embase databases. Heterogeneity in the studies included in the meta-analysis was evaluated using statistical tests such as the Chi-square test, I2, and forest plots. Publication bias was assessed using Begg's and Egger's tests.<h4>Results</h4>This investigation analyzed data from 42 studies conducted between 1985 and 2022, with a total of 3,377,816 participants. The meta-analysis demonstrated that the odds ratio (OR) of CTS in participants with a history of diabetes compared to those without was 1.90 (95% CI: 1.64-2.21; P-value < 0.001). Given that publication bias was observed in this study (Begg's test P-value = 0.01), the modified OR was calculated with consideration of missed studies, which was 1.68 (95% CI: 1.45-1.94; P-value < 0.001).<h4>Conclusion</h4>The results of this study suggest that diabetic patients have 90% higher odds of developing CTS compared to non-diabetic individuals, which is statistically significant.https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0299442&type=printable
spellingShingle Elaheh Sanjari
Hadi Raeisi Shahraki
Lusine G Khachatryan
Abdollah Mohammadian-Hafshejani
Investigating the association between diabetes and carpal tunnel syndrome: A systematic review and meta-analysis approach.
PLoS ONE
title Investigating the association between diabetes and carpal tunnel syndrome: A systematic review and meta-analysis approach.
title_full Investigating the association between diabetes and carpal tunnel syndrome: A systematic review and meta-analysis approach.
title_fullStr Investigating the association between diabetes and carpal tunnel syndrome: A systematic review and meta-analysis approach.
title_full_unstemmed Investigating the association between diabetes and carpal tunnel syndrome: A systematic review and meta-analysis approach.
title_short Investigating the association between diabetes and carpal tunnel syndrome: A systematic review and meta-analysis approach.
title_sort investigating the association between diabetes and carpal tunnel syndrome a systematic review and meta analysis approach
url https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0299442&type=printable
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AT lusinegkhachatryan investigatingtheassociationbetweendiabetesandcarpaltunnelsyndromeasystematicreviewandmetaanalysisapproach
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