Intron-derived small RNAs for silencing viral RNAs in mosquito cells.

Intron-derived small RNAs for silencing viral RNAs in mosquito cells.

Aedes aegypti and Ae. albopictus are the main vectors of mosquito-borne viruses of medical and veterinary significance. Many of these viruses have RNA genomes. Exogenously provided, e.g. transgene encoded, small RNAs could be used to inhibit virus replication, breaking the transmission cycle. We tes...

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Bibliographic Details
Main Authors: Priscilla Y L Tng, Leonela Z Carabajal Paladino, Michelle A E Anderson, Zach N Adelman, Rennos Fragkoudis, Rob Noad, Luke Alphey
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-06-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0010548&type=printable
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