Comparison of depression with anxious distress and melancholic depression from the perspective of psychomotor disturbance
Abstract Aim In the DSM‐5, it is specified that severe cases of major depressive disorder with anxious distress (ANXD) may be accompanied with motor agitation. Agitation, on the other hand, is one of the main characteristics of major depressive disorder with melancholic features (MEL). The purpose o...
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| Format: | Article |
| Language: | English |
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Wiley
2024-12-01
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| Series: | PCN Reports |
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| Online Access: | https://doi.org/10.1002/pcn5.70022 |
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| author | Yu Tamada Takeshi Inoue Atsushi Sekine Hiroyuki Toda Minoru Takeshima Masaaki Sasaki Yota Fujimura Susumu Ohmae |
| author_facet | Yu Tamada Takeshi Inoue Atsushi Sekine Hiroyuki Toda Minoru Takeshima Masaaki Sasaki Yota Fujimura Susumu Ohmae |
| author_sort | Yu Tamada |
| collection | DOAJ |
| description | Abstract Aim In the DSM‐5, it is specified that severe cases of major depressive disorder with anxious distress (ANXD) may be accompanied with motor agitation. Agitation, on the other hand, is one of the main characteristics of major depressive disorder with melancholic features (MEL). The purpose of this study was to compare ANXD and MEL in terms of psychomotor disturbance. Methods A total of 106 patients with major depressive disorder were included in the study. Psychomotor disturbance was assessed using the CORE measure. The associations of ANXD and MEL with the CORE measure subscales of psychomotor retardation, agitation, and noninteractiveness were analyzed using multivariate logistic analysis. Results Retardation scores (odds ratio [OR] = 0.63, 95% confidence interval [CI] = 0.52–0.77) were associated with fewer diagnoses of ANXD, whereas agitation scores (OR = 2.23, 95% CI = 1.60–3.13) were associated with more diagnoses of ANXD. Both noninteractiveness (OR = 1.23, 95% CI = 1.06–1.42) and agitation (OR = 1.27, 95% CI = 1.02–1.58) scores were associated with increased diagnoses of MEL. Conclusion Among the characteristics of psychomotor disturbance, agitation is a common feature of both ANXD and MEL, and ANXD and the agitated type of MEL may be overlapping concepts. On the other hand, ANXD is distinguished from the retarded type of MEL by its low level of retardation, whereas MEL but not ANXD is characterized by noninteractiveness. |
| format | Article |
| id | doaj-art-ff319b8c878f42afbb6ddbf5e24f8253 |
| institution | Kabale University |
| issn | 2769-2558 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Wiley |
| record_format | Article |
| series | PCN Reports |
| spelling | doaj-art-ff319b8c878f42afbb6ddbf5e24f82532025-01-03T11:15:26ZengWileyPCN Reports2769-25582024-12-0134n/an/a10.1002/pcn5.70022Comparison of depression with anxious distress and melancholic depression from the perspective of psychomotor disturbanceYu Tamada0Takeshi Inoue1Atsushi Sekine2Hiroyuki Toda3Minoru Takeshima4Masaaki Sasaki5Yota Fujimura6Susumu Ohmae7Department of Psychiatry Tokyo Medical University Hachioji Medical Center, Hachioji Tokyo JapanDepartment of Psychiatry Tokyo Medical University Tokyo JapanDepartment of Psychiatry, The Medical Foundation of Keishin‐Kai Kyouwa Hospital Daisen JapanDepartment of Psychiatry National Defense Medical College Tokorozawa JapanDepartment of Psychiatry Tokyo Medical University Tokyo JapanDepartment of Psychiatry Toranomon Hospital Kajigaya Kawasaki JapanDepartment of Psychiatry Tokyo Medical University Hachioji Medical Center, Hachioji Tokyo JapanDepartment of Psychiatry Toranomon Hospital Tokyo JapanAbstract Aim In the DSM‐5, it is specified that severe cases of major depressive disorder with anxious distress (ANXD) may be accompanied with motor agitation. Agitation, on the other hand, is one of the main characteristics of major depressive disorder with melancholic features (MEL). The purpose of this study was to compare ANXD and MEL in terms of psychomotor disturbance. Methods A total of 106 patients with major depressive disorder were included in the study. Psychomotor disturbance was assessed using the CORE measure. The associations of ANXD and MEL with the CORE measure subscales of psychomotor retardation, agitation, and noninteractiveness were analyzed using multivariate logistic analysis. Results Retardation scores (odds ratio [OR] = 0.63, 95% confidence interval [CI] = 0.52–0.77) were associated with fewer diagnoses of ANXD, whereas agitation scores (OR = 2.23, 95% CI = 1.60–3.13) were associated with more diagnoses of ANXD. Both noninteractiveness (OR = 1.23, 95% CI = 1.06–1.42) and agitation (OR = 1.27, 95% CI = 1.02–1.58) scores were associated with increased diagnoses of MEL. Conclusion Among the characteristics of psychomotor disturbance, agitation is a common feature of both ANXD and MEL, and ANXD and the agitated type of MEL may be overlapping concepts. On the other hand, ANXD is distinguished from the retarded type of MEL by its low level of retardation, whereas MEL but not ANXD is characterized by noninteractiveness.https://doi.org/10.1002/pcn5.70022agitationanxious depressionCORE measurenoninteractivenessretardation |
| spellingShingle | Yu Tamada Takeshi Inoue Atsushi Sekine Hiroyuki Toda Minoru Takeshima Masaaki Sasaki Yota Fujimura Susumu Ohmae Comparison of depression with anxious distress and melancholic depression from the perspective of psychomotor disturbance PCN Reports agitation anxious depression CORE measure noninteractiveness retardation |
| title | Comparison of depression with anxious distress and melancholic depression from the perspective of psychomotor disturbance |
| title_full | Comparison of depression with anxious distress and melancholic depression from the perspective of psychomotor disturbance |
| title_fullStr | Comparison of depression with anxious distress and melancholic depression from the perspective of psychomotor disturbance |
| title_full_unstemmed | Comparison of depression with anxious distress and melancholic depression from the perspective of psychomotor disturbance |
| title_short | Comparison of depression with anxious distress and melancholic depression from the perspective of psychomotor disturbance |
| title_sort | comparison of depression with anxious distress and melancholic depression from the perspective of psychomotor disturbance |
| topic | agitation anxious depression CORE measure noninteractiveness retardation |
| url | https://doi.org/10.1002/pcn5.70022 |
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