Dementia with lewy bodies patients with high tau levels display unique proteome profiles

Dementia with lewy bodies patients with high tau levels display unique proteome profiles

Abstract Background Clinical studies have long observed that neurodegenerative disorders display a range of symptoms and pathological features and, in some cases, overlap, suggesting that these diseases exist on a spectrum. Dementia with Lewy Bodies (DLB), a synucleinopathy, is a prominent example,...

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Bibliographic Details
Main Authors: Sinead Greally, Mukesh Kumar, Christoph Schlaffner, Hanne van der Heijden, Elisabeth S. Lawton, Deeptarup Biswas, Sabina Berretta, Hanno Steen, Judith A. Steen
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Molecular Neurodegeneration
Subjects:
Tau
α-synuclein
Neurodegeneration
Co-pathology
Proteomics
Mass spectrometry
Online Access:https://doi.org/10.1186/s13024-024-00782-0
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