Methods for Detection of Bacterial Endotoxin in Critical Care Medicine

Dedicated to reviewing the methods for detecting bacterial endotoxin in aqueous solutions and biological fluids, this review is focused on determining the content of endotoxin as a clinically relevant biomarker of sepsis caused by Gram-negative bacteria. The advantages and disadvantages of each meth...

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Main Authors: M. N. Kopitsyna, A. S. Morozov, I. V. Bessonov, V. M. Pisarev
Format: Article
Language:English
Published: Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia 2018-01-01
Series:Общая реаниматология
Subjects:
Online Access:https://www.reanimatology.com/rmt/article/view/1628
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author M. N. Kopitsyna
A. S. Morozov
I. V. Bessonov
V. M. Pisarev
author_facet M. N. Kopitsyna
A. S. Morozov
I. V. Bessonov
V. M. Pisarev
author_sort M. N. Kopitsyna
collection DOAJ
description Dedicated to reviewing the methods for detecting bacterial endotoxin in aqueous solutions and biological fluids, this review is focused on determining the content of endotoxin as a clinically relevant biomarker of sepsis caused by Gram-negative bacteria. The advantages and disadvantages of each method are described, and the characteristics of test systems currently used in clinical practice are listed and compared.
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institution Kabale University
issn 1813-9779
2411-7110
language English
publishDate 2018-01-01
publisher Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia
record_format Article
series Общая реаниматология
spelling doaj-art-fea6d3b4a79c40a09958b76a57bc62c12025-08-20T03:59:40ZengFederal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, RussiaОбщая реаниматология1813-97792411-71102018-01-0113510912010.15360/1813-9779-2017-5-109-1201586Methods for Detection of Bacterial Endotoxin in Critical Care MedicineM. N. Kopitsyna0A. S. Morozov1I. V. Bessonov2V. M. Pisarev3Joint-Stock Company Perspektivnye meditsinskie tekhnologiiJoint-Stock Company Perspektivnye meditsinskie tekhnologiiJoint-Stock Company Perspektivnye meditsinskie tekhnologiiV. A. Negovsky Research Institute of General Reanimatology, Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology; Central Research Institute of Epidemiology, RospotrebnadzorDedicated to reviewing the methods for detecting bacterial endotoxin in aqueous solutions and biological fluids, this review is focused on determining the content of endotoxin as a clinically relevant biomarker of sepsis caused by Gram-negative bacteria. The advantages and disadvantages of each method are described, and the characteristics of test systems currently used in clinical practice are listed and compared.https://www.reanimatology.com/rmt/article/view/1628bacterial endotoxinlipopolysaccharidegram-negative bacteriasepsislal-testendotoxin activity assaymethod of activated particles
spellingShingle M. N. Kopitsyna
A. S. Morozov
I. V. Bessonov
V. M. Pisarev
Methods for Detection of Bacterial Endotoxin in Critical Care Medicine
Общая реаниматология
bacterial endotoxin
lipopolysaccharide
gram-negative bacteria
sepsis
lal-test
endotoxin activity assay
method of activated particles
title Methods for Detection of Bacterial Endotoxin in Critical Care Medicine
title_full Methods for Detection of Bacterial Endotoxin in Critical Care Medicine
title_fullStr Methods for Detection of Bacterial Endotoxin in Critical Care Medicine
title_full_unstemmed Methods for Detection of Bacterial Endotoxin in Critical Care Medicine
title_short Methods for Detection of Bacterial Endotoxin in Critical Care Medicine
title_sort methods for detection of bacterial endotoxin in critical care medicine
topic bacterial endotoxin
lipopolysaccharide
gram-negative bacteria
sepsis
lal-test
endotoxin activity assay
method of activated particles
url https://www.reanimatology.com/rmt/article/view/1628
work_keys_str_mv AT mnkopitsyna methodsfordetectionofbacterialendotoxinincriticalcaremedicine
AT asmorozov methodsfordetectionofbacterialendotoxinincriticalcaremedicine
AT ivbessonov methodsfordetectionofbacterialendotoxinincriticalcaremedicine
AT vmpisarev methodsfordetectionofbacterialendotoxinincriticalcaremedicine