Antibiotic resistance mediated by gene amplifications

Abstract Apart from horizontal gene transfer and sequence-altering mutational events, antibiotic resistance can emerge due to the formation of tandem repeats of genomic regions. This phenomenon, also known as gene amplification, has been implicated in antibiotic resistance in both laboratory and cli...

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Bibliographic Details
Main Authors: Kalinga Pavan T. Silva, Anupama Khare
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:npj Antimicrobials and Resistance
Online Access:https://doi.org/10.1038/s44259-024-00052-5
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