Measurement of neurodegeneration using a multivariate early frame amyloid PET classifier

Measurement of neurodegeneration using a multivariate early frame amyloid PET classifier

Abstract Introduction Amyloid measurement provides important confirmation of pathology for Alzheimer's disease (AD) clinical trials. However, many amyloid positive (Am+) early‐stage subjects do not worsen clinically during a clinical trial, and a neurodegenerative measure predictive of decline...

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Bibliographic Details
Main Authors: Dawn C. Matthews, Ana S. Lukic, Randolph D. Andrews, Miles N. Wernick, Stephen C. Strother, Mark E. Schmidt, for the Alzheimer's Disease Neuroimaging Initiative
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Alzheimer’s & Dementia: Translational Research & Clinical Interventions
Subjects:
Alzheimer's disease
amyloid
early frame amyloid
EFA
fluorodeoxyglucose
machine learning
Online Access:https://doi.org/10.1002/trc2.12325
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