Unveiling the Mysteries of the Chinese lens zonule balance tension: A statistical analysis

Background: This study aims to provide an estimated dataset of lens zonule balance tension (LZBT) measurements in cataractous lenses among Chinese patients and to conduct a statistical analysis of anterior segment parameters. Methods: This is a cross-sectional study. We included a total of 833 eyes...

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Main Authors: Lujie Zhang, Kai Wen, Ming Liu, Jie Wang, Yifang Huang, Yufeng Zhang, Ruihua Wei, Jing Sun
Format: Article
Language:English
Published: Elsevier 2024-10-01
Series:Heliyon
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Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024147433
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author Lujie Zhang
Kai Wen
Ming Liu
Jie Wang
Yifang Huang
Yufeng Zhang
Ruihua Wei
Jing Sun
author_facet Lujie Zhang
Kai Wen
Ming Liu
Jie Wang
Yifang Huang
Yufeng Zhang
Ruihua Wei
Jing Sun
author_sort Lujie Zhang
collection DOAJ
description Background: This study aims to provide an estimated dataset of lens zonule balance tension (LZBT) measurements in cataractous lenses among Chinese patients and to conduct a statistical analysis of anterior segment parameters. Methods: This is a cross-sectional study. We included a total of 833 eyes from 833 Chinese participants aged 23–91 years who underwent cataract surgery. Anterior segment parameters were measured using swept-source anterior segment optical coherence tomography (SS-AS OCT) to calculate lens gravity (LG) and crystalline lens volume (VOL). Axial length (AL) was measured using IOL-Master 700. LZBT was calculated using force decomposition and synthesis methods. Results: The mean LZBT in the horizontal direction was 8.48E-05 ± 3.23E-05 N across all eyes. The LZBT in the subtemporal-supraspinal and supraspinal-temporal directions was 2 times greater than in the vertical direction. The balanced force on the suspensory ligament in the horizontal direction was twice as strong as in the vertical direction. Additionally, anterior segment parameters such as lens equivalent diameter (LE-dia), radius of the anterior lens surface curvature (RAL), radius of the posterior lens surface curvature (RPL), anterior chamber depth (ACD), iris area, iris volume, and iris thickness showed positive correlations with AL. Conclusions: Accounting for gravitational effects, we concluded that zonule force is asymmetrically distributed. Importantly, this study establishes the normal range of LZBT across different meridians using force synthesis and decomposition, offering new insights and feasibility for studying suspensory ligament biomechanics.
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spelling doaj-art-fe75182cd10c407994cdf2557cbaa03d2024-11-12T05:19:11ZengElsevierHeliyon2405-84402024-10-011020e38712Unveiling the Mysteries of the Chinese lens zonule balance tension: A statistical analysisLujie Zhang0Kai Wen1Ming Liu2Jie Wang3Yifang Huang4Yufeng Zhang5Ruihua Wei6Jing Sun7Tianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital, China; Tianjin Children's Hospital, Tianjin Key Laboratory of Birth Defects for Prevention and Treatment, ChinaTianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital, ChinaTianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital, ChinaTianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital, ChinaTianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital, ChinaTianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital, ChinaTianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital, China; Corresponding author. No. 251, Fukang Road, Nankai District, Tianjin, 300110, China.Tianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital, China; Corresponding author. No. 251, Fukang Road, Nankai District, Tianjin, 300110, China .Background: This study aims to provide an estimated dataset of lens zonule balance tension (LZBT) measurements in cataractous lenses among Chinese patients and to conduct a statistical analysis of anterior segment parameters. Methods: This is a cross-sectional study. We included a total of 833 eyes from 833 Chinese participants aged 23–91 years who underwent cataract surgery. Anterior segment parameters were measured using swept-source anterior segment optical coherence tomography (SS-AS OCT) to calculate lens gravity (LG) and crystalline lens volume (VOL). Axial length (AL) was measured using IOL-Master 700. LZBT was calculated using force decomposition and synthesis methods. Results: The mean LZBT in the horizontal direction was 8.48E-05 ± 3.23E-05 N across all eyes. The LZBT in the subtemporal-supraspinal and supraspinal-temporal directions was 2 times greater than in the vertical direction. The balanced force on the suspensory ligament in the horizontal direction was twice as strong as in the vertical direction. Additionally, anterior segment parameters such as lens equivalent diameter (LE-dia), radius of the anterior lens surface curvature (RAL), radius of the posterior lens surface curvature (RPL), anterior chamber depth (ACD), iris area, iris volume, and iris thickness showed positive correlations with AL. Conclusions: Accounting for gravitational effects, we concluded that zonule force is asymmetrically distributed. Importantly, this study establishes the normal range of LZBT across different meridians using force synthesis and decomposition, offering new insights and feasibility for studying suspensory ligament biomechanics.http://www.sciencedirect.com/science/article/pii/S2405844024147433Lens zonules balance tensionLens gravityLens volume
spellingShingle Lujie Zhang
Kai Wen
Ming Liu
Jie Wang
Yifang Huang
Yufeng Zhang
Ruihua Wei
Jing Sun
Unveiling the Mysteries of the Chinese lens zonule balance tension: A statistical analysis
Heliyon
Lens zonules balance tension
Lens gravity
Lens volume
title Unveiling the Mysteries of the Chinese lens zonule balance tension: A statistical analysis
title_full Unveiling the Mysteries of the Chinese lens zonule balance tension: A statistical analysis
title_fullStr Unveiling the Mysteries of the Chinese lens zonule balance tension: A statistical analysis
title_full_unstemmed Unveiling the Mysteries of the Chinese lens zonule balance tension: A statistical analysis
title_short Unveiling the Mysteries of the Chinese lens zonule balance tension: A statistical analysis
title_sort unveiling the mysteries of the chinese lens zonule balance tension a statistical analysis
topic Lens zonules balance tension
Lens gravity
Lens volume
url http://www.sciencedirect.com/science/article/pii/S2405844024147433
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