Impact of terminal ileal microbiota dysbiosis and tryptophan metabolism alterations on mental disorders in patients with Crohn’s disease

Abstract Background Crohn’s disease (CD) is a chronic non-specific inflammatory bowel disease with an increasing incidence worldwide. Patients with CD are facing elevated risk for mental disorders (MD) than healthy people, and chronic psychological stress is considered to trigger deterioration and r...

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Main Authors: Yin Lin, Fang-Tao Wang, Kai Xia, Ren-Yuan Gao, Yi-Ran Jiao, Min Fang, Chun-Qiu Chen
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Gastroenterology
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Online Access:https://doi.org/10.1186/s12876-025-04007-6
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