Transcanalicular laser-assisted and external dacryocystorhinostomy anatomical and functional success in primary acquired nasolacrimal duct obstruction: systematic review and meta-analysis
Abstract Background Primary acquired nasolacrimal duct obstruction (PANDO) is a condition in which tear ducts are blocked, leading to epiphora and dacryocystitis. This systematic review and meta-analysis aimed to measure the ability of transcanalicular dacryocystorhinostomy (TC-DCR) as an alternativ...
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2025-01-01
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Online Access: | https://doi.org/10.1186/s12886-024-03818-7 |
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author | Khalid W. Helmi Ahmed S. Abdulhamid Mohammed S. Alomari Ali S. Alsudais Badran S. Alqurashi Abdullah Alsharif Abdulrahman H. Alzahrani Abdulrahman M. Bahalaq Mohammed F. Qutub Hashem S. Almarzouki |
author_facet | Khalid W. Helmi Ahmed S. Abdulhamid Mohammed S. Alomari Ali S. Alsudais Badran S. Alqurashi Abdullah Alsharif Abdulrahman H. Alzahrani Abdulrahman M. Bahalaq Mohammed F. Qutub Hashem S. Almarzouki |
author_sort | Khalid W. Helmi |
collection | DOAJ |
description | Abstract Background Primary acquired nasolacrimal duct obstruction (PANDO) is a condition in which tear ducts are blocked, leading to epiphora and dacryocystitis. This systematic review and meta-analysis aimed to measure the ability of transcanalicular dacryocystorhinostomy (TC-DCR) as an alternative approach to PANDO compared to traditional external dacryocystorhinostomy (EX-DCR). Methods Our search included Embase, Medline, and the Cochrane Central Register of Controlled Trials (CENTRAL). We included only observational studies, randomized controlled trials (RCTs), and quasi-experimental studies that compared TC-DCR and EX-DCR. The outcomes measured were anatomical and functional success rates, intraoperative complications, postoperative complications, and surgical time. Statistically significant results were determined as a p value of less than 0.05; thus, a confidence interval of 95% was used. Dichotomous outcomes were reported via risk ratios (RR), whereas continuous outcomes were reported using standardized mean differences (SMD). Results There was a statistically significant difference in anatomical success (RR = 0.84, 95% CI 0.72–0.97; P = 0.02), favoring EX-DCR; functional success (RR = 0.87, 95% CI 0.78–0.97; P = 0.01), favoring EX-DCR; operative (OR) time (SMD = -2.42, 95% CI -2.92 – -1.91; P < 0.00001) favoring TC-DCR; and intraoperative complications (RR = 0.16, 95% CI 0.06–0.43; P = 0.0003), favoring TC-DCR. Moreover, the subgroup analysis comparing single-diode TC-DCR to EX-DCR revealed a statistically significant difference in terms of anatomical success and functional success; however, the comparison of multidiode TC-DCR to EX-DCR revealed no statistically significant difference. Conclusions More research should be conducted to compare the anatomical and functional success of muli-diode TC-DCR with EX-DCR because the analysis performed comparing them revealed no statistical significance. |
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spelling | doaj-art-fdf2bc4e2bb4420c81f173d8fc0b5be62025-01-12T12:12:21ZengBMCBMC Ophthalmology1471-24152025-01-012511910.1186/s12886-024-03818-7Transcanalicular laser-assisted and external dacryocystorhinostomy anatomical and functional success in primary acquired nasolacrimal duct obstruction: systematic review and meta-analysisKhalid W. Helmi0Ahmed S. Abdulhamid1Mohammed S. Alomari2Ali S. Alsudais3Badran S. Alqurashi4Abdullah Alsharif5Abdulrahman H. Alzahrani6Abdulrahman M. Bahalaq7Mohammed F. Qutub8Hashem S. Almarzouki9College of Medicine, King Saud Bin Abdulaziz University for Health SciencesCollege of Medicine, King Saud Bin Abdulaziz University for Health SciencesCollege of Medicine, King Saud Bin Abdulaziz University for Health SciencesCollege of Medicine, King Saud Bin Abdulaziz University for Health SciencesCollege of Medicine, King Abdulaziz UniversityCollege of Medicine, King Saud Bin Abdulaziz University for Health SciencesCollege of Medicine, King Saud Bin Abdulaziz University for Health SciencesCollege of Medicine, King Saud Bin Abdulaziz University for Health SciencesCollege of Medicine, King Saud Bin Abdulaziz University for Health SciencesCollege of Medicine, King Saud Bin Abdulaziz University for Health SciencesAbstract Background Primary acquired nasolacrimal duct obstruction (PANDO) is a condition in which tear ducts are blocked, leading to epiphora and dacryocystitis. This systematic review and meta-analysis aimed to measure the ability of transcanalicular dacryocystorhinostomy (TC-DCR) as an alternative approach to PANDO compared to traditional external dacryocystorhinostomy (EX-DCR). Methods Our search included Embase, Medline, and the Cochrane Central Register of Controlled Trials (CENTRAL). We included only observational studies, randomized controlled trials (RCTs), and quasi-experimental studies that compared TC-DCR and EX-DCR. The outcomes measured were anatomical and functional success rates, intraoperative complications, postoperative complications, and surgical time. Statistically significant results were determined as a p value of less than 0.05; thus, a confidence interval of 95% was used. Dichotomous outcomes were reported via risk ratios (RR), whereas continuous outcomes were reported using standardized mean differences (SMD). Results There was a statistically significant difference in anatomical success (RR = 0.84, 95% CI 0.72–0.97; P = 0.02), favoring EX-DCR; functional success (RR = 0.87, 95% CI 0.78–0.97; P = 0.01), favoring EX-DCR; operative (OR) time (SMD = -2.42, 95% CI -2.92 – -1.91; P < 0.00001) favoring TC-DCR; and intraoperative complications (RR = 0.16, 95% CI 0.06–0.43; P = 0.0003), favoring TC-DCR. Moreover, the subgroup analysis comparing single-diode TC-DCR to EX-DCR revealed a statistically significant difference in terms of anatomical success and functional success; however, the comparison of multidiode TC-DCR to EX-DCR revealed no statistically significant difference. Conclusions More research should be conducted to compare the anatomical and functional success of muli-diode TC-DCR with EX-DCR because the analysis performed comparing them revealed no statistical significance.https://doi.org/10.1186/s12886-024-03818-7Transcanalicular dacryocystorhinostomyExternal dacryocystorhinostomyNasolacrimal duct obstruction |
spellingShingle | Khalid W. Helmi Ahmed S. Abdulhamid Mohammed S. Alomari Ali S. Alsudais Badran S. Alqurashi Abdullah Alsharif Abdulrahman H. Alzahrani Abdulrahman M. Bahalaq Mohammed F. Qutub Hashem S. Almarzouki Transcanalicular laser-assisted and external dacryocystorhinostomy anatomical and functional success in primary acquired nasolacrimal duct obstruction: systematic review and meta-analysis BMC Ophthalmology Transcanalicular dacryocystorhinostomy External dacryocystorhinostomy Nasolacrimal duct obstruction |
title | Transcanalicular laser-assisted and external dacryocystorhinostomy anatomical and functional success in primary acquired nasolacrimal duct obstruction: systematic review and meta-analysis |
title_full | Transcanalicular laser-assisted and external dacryocystorhinostomy anatomical and functional success in primary acquired nasolacrimal duct obstruction: systematic review and meta-analysis |
title_fullStr | Transcanalicular laser-assisted and external dacryocystorhinostomy anatomical and functional success in primary acquired nasolacrimal duct obstruction: systematic review and meta-analysis |
title_full_unstemmed | Transcanalicular laser-assisted and external dacryocystorhinostomy anatomical and functional success in primary acquired nasolacrimal duct obstruction: systematic review and meta-analysis |
title_short | Transcanalicular laser-assisted and external dacryocystorhinostomy anatomical and functional success in primary acquired nasolacrimal duct obstruction: systematic review and meta-analysis |
title_sort | transcanalicular laser assisted and external dacryocystorhinostomy anatomical and functional success in primary acquired nasolacrimal duct obstruction systematic review and meta analysis |
topic | Transcanalicular dacryocystorhinostomy External dacryocystorhinostomy Nasolacrimal duct obstruction |
url | https://doi.org/10.1186/s12886-024-03818-7 |
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