Transcanalicular laser-assisted and external dacryocystorhinostomy anatomical and functional success in primary acquired nasolacrimal duct obstruction: systematic review and meta-analysis

Abstract Background Primary acquired nasolacrimal duct obstruction (PANDO) is a condition in which tear ducts are blocked, leading to epiphora and dacryocystitis. This systematic review and meta-analysis aimed to measure the ability of transcanalicular dacryocystorhinostomy (TC-DCR) as an alternativ...

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Main Authors: Khalid W. Helmi, Ahmed S. Abdulhamid, Mohammed S. Alomari, Ali S. Alsudais, Badran S. Alqurashi, Abdullah Alsharif, Abdulrahman H. Alzahrani, Abdulrahman M. Bahalaq, Mohammed F. Qutub, Hashem S. Almarzouki
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Language:English
Published: BMC 2025-01-01
Series:BMC Ophthalmology
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Online Access:https://doi.org/10.1186/s12886-024-03818-7
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author Khalid W. Helmi
Ahmed S. Abdulhamid
Mohammed S. Alomari
Ali S. Alsudais
Badran S. Alqurashi
Abdullah Alsharif
Abdulrahman H. Alzahrani
Abdulrahman M. Bahalaq
Mohammed F. Qutub
Hashem S. Almarzouki
author_facet Khalid W. Helmi
Ahmed S. Abdulhamid
Mohammed S. Alomari
Ali S. Alsudais
Badran S. Alqurashi
Abdullah Alsharif
Abdulrahman H. Alzahrani
Abdulrahman M. Bahalaq
Mohammed F. Qutub
Hashem S. Almarzouki
author_sort Khalid W. Helmi
collection DOAJ
description Abstract Background Primary acquired nasolacrimal duct obstruction (PANDO) is a condition in which tear ducts are blocked, leading to epiphora and dacryocystitis. This systematic review and meta-analysis aimed to measure the ability of transcanalicular dacryocystorhinostomy (TC-DCR) as an alternative approach to PANDO compared to traditional external dacryocystorhinostomy (EX-DCR). Methods Our search included Embase, Medline, and the Cochrane Central Register of Controlled Trials (CENTRAL). We included only observational studies, randomized controlled trials (RCTs), and quasi-experimental studies that compared TC-DCR and EX-DCR. The outcomes measured were anatomical and functional success rates, intraoperative complications, postoperative complications, and surgical time. Statistically significant results were determined as a p value of less than 0.05; thus, a confidence interval of 95% was used. Dichotomous outcomes were reported via risk ratios (RR), whereas continuous outcomes were reported using standardized mean differences (SMD). Results There was a statistically significant difference in anatomical success (RR = 0.84, 95% CI 0.72–0.97; P = 0.02), favoring EX-DCR; functional success (RR = 0.87, 95% CI 0.78–0.97; P = 0.01), favoring EX-DCR; operative (OR) time (SMD = -2.42, 95% CI -2.92 – -1.91; P < 0.00001) favoring TC-DCR; and intraoperative complications (RR = 0.16, 95% CI 0.06–0.43; P = 0.0003), favoring TC-DCR. Moreover, the subgroup analysis comparing single-diode TC-DCR to EX-DCR revealed a statistically significant difference in terms of anatomical success and functional success; however, the comparison of multidiode TC-DCR to EX-DCR revealed no statistically significant difference. Conclusions More research should be conducted to compare the anatomical and functional success of muli-diode TC-DCR with EX-DCR because the analysis performed comparing them revealed no statistical significance.
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spelling doaj-art-fdf2bc4e2bb4420c81f173d8fc0b5be62025-01-12T12:12:21ZengBMCBMC Ophthalmology1471-24152025-01-012511910.1186/s12886-024-03818-7Transcanalicular laser-assisted and external dacryocystorhinostomy anatomical and functional success in primary acquired nasolacrimal duct obstruction: systematic review and meta-analysisKhalid W. Helmi0Ahmed S. Abdulhamid1Mohammed S. Alomari2Ali S. Alsudais3Badran S. Alqurashi4Abdullah Alsharif5Abdulrahman H. Alzahrani6Abdulrahman M. Bahalaq7Mohammed F. Qutub8Hashem S. Almarzouki9College of Medicine, King Saud Bin Abdulaziz University for Health SciencesCollege of Medicine, King Saud Bin Abdulaziz University for Health SciencesCollege of Medicine, King Saud Bin Abdulaziz University for Health SciencesCollege of Medicine, King Saud Bin Abdulaziz University for Health SciencesCollege of Medicine, King Abdulaziz UniversityCollege of Medicine, King Saud Bin Abdulaziz University for Health SciencesCollege of Medicine, King Saud Bin Abdulaziz University for Health SciencesCollege of Medicine, King Saud Bin Abdulaziz University for Health SciencesCollege of Medicine, King Saud Bin Abdulaziz University for Health SciencesCollege of Medicine, King Saud Bin Abdulaziz University for Health SciencesAbstract Background Primary acquired nasolacrimal duct obstruction (PANDO) is a condition in which tear ducts are blocked, leading to epiphora and dacryocystitis. This systematic review and meta-analysis aimed to measure the ability of transcanalicular dacryocystorhinostomy (TC-DCR) as an alternative approach to PANDO compared to traditional external dacryocystorhinostomy (EX-DCR). Methods Our search included Embase, Medline, and the Cochrane Central Register of Controlled Trials (CENTRAL). We included only observational studies, randomized controlled trials (RCTs), and quasi-experimental studies that compared TC-DCR and EX-DCR. The outcomes measured were anatomical and functional success rates, intraoperative complications, postoperative complications, and surgical time. Statistically significant results were determined as a p value of less than 0.05; thus, a confidence interval of 95% was used. Dichotomous outcomes were reported via risk ratios (RR), whereas continuous outcomes were reported using standardized mean differences (SMD). Results There was a statistically significant difference in anatomical success (RR = 0.84, 95% CI 0.72–0.97; P = 0.02), favoring EX-DCR; functional success (RR = 0.87, 95% CI 0.78–0.97; P = 0.01), favoring EX-DCR; operative (OR) time (SMD = -2.42, 95% CI -2.92 – -1.91; P < 0.00001) favoring TC-DCR; and intraoperative complications (RR = 0.16, 95% CI 0.06–0.43; P = 0.0003), favoring TC-DCR. Moreover, the subgroup analysis comparing single-diode TC-DCR to EX-DCR revealed a statistically significant difference in terms of anatomical success and functional success; however, the comparison of multidiode TC-DCR to EX-DCR revealed no statistically significant difference. Conclusions More research should be conducted to compare the anatomical and functional success of muli-diode TC-DCR with EX-DCR because the analysis performed comparing them revealed no statistical significance.https://doi.org/10.1186/s12886-024-03818-7Transcanalicular dacryocystorhinostomyExternal dacryocystorhinostomyNasolacrimal duct obstruction
spellingShingle Khalid W. Helmi
Ahmed S. Abdulhamid
Mohammed S. Alomari
Ali S. Alsudais
Badran S. Alqurashi
Abdullah Alsharif
Abdulrahman H. Alzahrani
Abdulrahman M. Bahalaq
Mohammed F. Qutub
Hashem S. Almarzouki
Transcanalicular laser-assisted and external dacryocystorhinostomy anatomical and functional success in primary acquired nasolacrimal duct obstruction: systematic review and meta-analysis
BMC Ophthalmology
Transcanalicular dacryocystorhinostomy
External dacryocystorhinostomy
Nasolacrimal duct obstruction
title Transcanalicular laser-assisted and external dacryocystorhinostomy anatomical and functional success in primary acquired nasolacrimal duct obstruction: systematic review and meta-analysis
title_full Transcanalicular laser-assisted and external dacryocystorhinostomy anatomical and functional success in primary acquired nasolacrimal duct obstruction: systematic review and meta-analysis
title_fullStr Transcanalicular laser-assisted and external dacryocystorhinostomy anatomical and functional success in primary acquired nasolacrimal duct obstruction: systematic review and meta-analysis
title_full_unstemmed Transcanalicular laser-assisted and external dacryocystorhinostomy anatomical and functional success in primary acquired nasolacrimal duct obstruction: systematic review and meta-analysis
title_short Transcanalicular laser-assisted and external dacryocystorhinostomy anatomical and functional success in primary acquired nasolacrimal duct obstruction: systematic review and meta-analysis
title_sort transcanalicular laser assisted and external dacryocystorhinostomy anatomical and functional success in primary acquired nasolacrimal duct obstruction systematic review and meta analysis
topic Transcanalicular dacryocystorhinostomy
External dacryocystorhinostomy
Nasolacrimal duct obstruction
url https://doi.org/10.1186/s12886-024-03818-7
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