信号转导与转录激活因子4基因多态性与子痫前期的相关性研究
【目的】探讨信号转导与转录激活因子4(STAT4)基因rs10181656及rs16833431位点多态性与子痫前期相关性 的关系。【方法】应用聚合酶链反应-限制性片段长度多态性法检测228名子痫前期患者(病例组)和179名健康孕妇(对照 组)的STAT4基因rs10181656 C/G及rs16833431 C/T位点的基因型频率。【结果】①rs10181656位点在病例组中C/C、C/G及G/ G基因型频率分别是35.96%、47.81%及16.23%,而对照组中的三种基因型的频率分别是46.37%、44.69%及8.94%,C/C、C/ G及G/G基因型频率在病例组和对照组中分布...
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Main Authors: | , , , , , |
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Format: | Article |
Language: | zho |
Published: |
Editorial Office of Journal of Sun Yat-sen University
2017-01-01
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Series: | Zhongshan Daxue xuebao. Yixue kexue ban |
Subjects: | |
Online Access: | http://xuebaoyx.sysu.edu.cn/zh/article/43568040/ |
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