Inhibition of Matrix Metalloproteinase-7 Attenuates Subpleural Fibrosis in Rheumatoid Arthritis-Associated Interstitial Lung Disease

Inhibition of Matrix Metalloproteinase-7 Attenuates Subpleural Fibrosis in Rheumatoid Arthritis-Associated Interstitial Lung Disease

<b>Background</b>: Rheumatoid arthritis-related interstitial lung disease (RA-ILD) is a significant complication of RA which lacks effective treatments with high mortality. This study aimed to investigate the role of matrix metalloproteinase-7 (MMP-7) in mediating RA-ILD. <b>Method...

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Main Authors: Li Xiong, Li-Mei Liang, Shu-Yi Ye, Xiao-Lin Cui, Shi-He Hu, Chen-Yue Lian, Wen-Jia Sun, Yang-Ping Lv, He-De Zhang, Meng Wang, Fei Xiang, Liang Xiong, Hong Ye, Wan-Li Ma, Lin-Jie Song
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Biomedicines
Subjects:
rheumatic diseases
rheumatoid arthritis
RA-ILD
pleural fibrosis
collagen-I
MMP-7
Online Access:https://www.mdpi.com/2227-9059/13/7/1581
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