Targeting histone deacetylase 6 mediates a dual anti‐melanoma effect: Enhanced antitumor immunity and impaired cell proliferation
The median survival for metastatic melanoma is in the realm of 8–16 months and there are few therapies that offer significant improvement in overall survival. One of the recent advances in cancer treatment focuses on epigenetic modifiers to alter the survivability and immunogenicity of cancer cells....
Saved in:
| Main Authors: | K.V. Woan, M. Lienlaf, P. Perez-Villaroel, C. Lee, F. Cheng, T. Knox, D.M. Woods, K. Barrios, J. Powers, E. Sahakian, H.W. Wang, J. Canales, D. Marante, K.S.M. Smalley, J. Bergman, E. Seto, A. Kozikowski, J. Pinilla-Ibarz, A. Sarnaik, E. Celis, J. Weber, E.M. Sotomayor, A. Villagra |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2015-08-01
|
| Series: | Molecular Oncology |
| Subjects: | |
| Online Access: | https://doi.org/10.1016/j.molonc.2015.04.002 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Progress of deacetylase SIRTs in pathogenesis of Parkinson's disease
by: FANG Xue, SHI Jin, LI Haining, YANG Juan
Published: (2024-11-01) -
Unveiling the role of histone deacetylases in neurological diseases: focus on epilepsy
by: Dan-Feng Cao, et al.
Published: (2024-11-01) -
Characterization of novel cold-active chitin deacetylase for green production of bioactive chitosan
by: Mohamed N. Abd El-Ghany, et al.
Published: (2025-01-01) -
Characterization of extracellular chitin deacetylase from Aneurinibacillus aneurinilyticus isolated from marine crustacean shell
by: Poonam Das, et al.
Published: (2025-01-01) -
P-glycoprotein and/or Histone Deacetylase 2 Regulates Steroid Responsiveness in Childhood Nephrotic Syndrome
by: Harshit Singh, et al.
Published: (2020-01-01)