Associations of NPPA promoter true methylation and hydroxymethylation with ischemic stroke and its functional outcome

Associations of NPPA promoter true methylation and hydroxymethylation with ischemic stroke and its functional outcome

Abstract Background Atrial natriuretic peptide (ANP) has been associated with ischemic stroke (IS), but the underlying molecular mechanisms are not clear. The objective of this study was to examine whether DNA methylation and hydroxymethylation in the coding gene of ANP (NPPA) were associated with I...

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Main Authors: Jialing Yao, Linghua Song, Jun Jiang, Jianan Zhang, Linan Chen, Wenxiu Fan, Ying Lu, Xiaolong Zhang, Jiexiang Jing, Yibing Jin, Mingzhi Zhang, Yongang Hao, Hao Peng
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Epigenetics Communications
Subjects:
Atrial natriuretic peptide
DNA methylation
DNA hydroxymethylation
Ischemic stroke
Online Access:https://doi.org/10.1186/s43682-024-00029-5
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