Exosomal PSM-E inhibits macrophage M2 polarization to suppress prostate cancer metastasis through the RACK1 signaling axis

Exosomal PSM-E inhibits macrophage M2 polarization to suppress prostate cancer metastasis through the RACK1 signaling axis

Abstract Background It is well-established that understanding the mechanism of prostate cancer (PCa)-associated metastasis is paramount for improving its prognosis. Metastasis is known to involve the communication between tumor-associated macrophages (TAMs) and tumor cells. Exosomes are crucial in m...

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Main Authors: Xingliang Qin, Ruoxi Niu, Yongyao Tan, Yuxin Huang, Weishu Ren, Weiwei Zhou, Huiquan Wu, Junlong Zhang, Mingze Xu, Xiang Zhou, Hongyu Guan, Xun Zhu, Yu Chen, Kaiyuan Cao
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Biomarker Research
Subjects:
Prostate cancer
Exosome
PSM-E
Macrophage polarization
Online Access:https://doi.org/10.1186/s40364-024-00685-8
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https://doi.org/10.1186/s40364-024-00685-8

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