The Use of Tissue Concentrations of Biological and Small-Molecule Therapies in Clinical Studies of Inflammatory Bowel Diseases

The Use of Tissue Concentrations of Biological and Small-Molecule Therapies in Clinical Studies of Inflammatory Bowel Diseases

<b>Abstract:</b> The introduction of biological therapies has revolutionized inflammatory bowel disease (IBD) management. A critical consideration in developing these therapies is ensuring adequate drug concentrations at the site of action. While blood-based biomarkers have shown limited...

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Bibliographic Details
Main Authors: Ahmed B. Bayoumy, Luc J. J. Derijks, Bas Oldenburg, Nanne K. H. de Boer
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Pharmaceutics
Subjects:
inflammatory bowel disease
tissue concentrations
infliximab
ustekinumab
vedolizumab
methotrexate
Online Access:https://www.mdpi.com/1999-4923/16/12/1497
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