In vitro and in silico Anti-diabetes mechanism of phytochemicals from Curculigo pilosa and its pharmacokinetic profiling via α-amylase inhibition

In vitro and in silico Anti-diabetes mechanism of phytochemicals from Curculigo pilosa and its pharmacokinetic profiling via α-amylase inhibition

Diabetes mellitus is characterized by elevated blood glucose resulting from carbohydrate metabolism via glucose metabolizing enzymes such as α-amylase. Curculigo pilosa is traditionally used as herbal medication as anti-diabetes therapy but its mechanism of action is yet to be explored. This study i...

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Bibliographic Details
Main Authors: Damilola A. Omoboyowa, Temitope C. Aribigbola, Simbo T. Akinsulure, Damilola S. Bodun, Ezekiel A. Olugbogi, Ebenezer A. Oni
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Aspects of Molecular Medicine
Subjects:
Diabetes
Curculigoside
α-amylase
In silico
In vitro
Online Access:http://www.sciencedirect.com/science/article/pii/S2949688825000024
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