The effects of digoxin on heart failure mortality and re-admission in a single center cross-sectional study

Introduction: Mortality benefit of digoxin prescription in patients suffering from heart failure has been questioned many time. We evaluated these effects among admitted symptomatic heart failure patients. Methods: We retrospectively divided our patients into two groups: group A (n=205) were digoxin...

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Main Authors: Mahsa Behnemoon, Zahra Borumandkia
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2024-09-01
Series:Journal of Cardiovascular and Thoracic Research
Subjects:
Online Access:https://jcvtr.tbzmed.ac.ir/PDF/jcvtr-16-194.pdf
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author Mahsa Behnemoon
Zahra Borumandkia
author_facet Mahsa Behnemoon
Zahra Borumandkia
author_sort Mahsa Behnemoon
collection DOAJ
description Introduction: Mortality benefit of digoxin prescription in patients suffering from heart failure has been questioned many time. We evaluated these effects among admitted symptomatic heart failure patients. Methods: We retrospectively divided our patients into two groups: group A (n=205) were digoxin prescribed, and group B (n=96) were digoxin naïve patients. Both groups’ medical records were gathered for one year, and the study endpoints were compared between the two groups. Results: The mean age was 62.3±12.1 years and 54.8 % were male. All-cause mortality and readmission occurred in 26.7% and 31.7% of individuals, respectively, without significant differences between the two groups. However, in subgroup analysis, there was a significant relationship between in-hospital mortality and the presence of cardiovascular risk factors. Conclusion: Digoxin might increase in-hospital mortality in patients with underlying cardiovascular risk factors.
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series Journal of Cardiovascular and Thoracic Research
spelling doaj-art-fd51d6e1a61c409f902fbe4559bd9bb72024-11-24T09:40:14ZengTabriz University of Medical SciencesJournal of Cardiovascular and Thoracic Research2008-51172008-68302024-09-0116319419710.34172/jcvtr.33062jcvtr-33062The effects of digoxin on heart failure mortality and re-admission in a single center cross-sectional studyMahsa Behnemoon0Zahra Borumandkia1Department of Cardiology, School of Medicine, Urmia University of Medical Sciences, Urmia, IranMedical Center, Urmia University of Medical Sciences, Urmia, IranIntroduction: Mortality benefit of digoxin prescription in patients suffering from heart failure has been questioned many time. We evaluated these effects among admitted symptomatic heart failure patients. Methods: We retrospectively divided our patients into two groups: group A (n=205) were digoxin prescribed, and group B (n=96) were digoxin naïve patients. Both groups’ medical records were gathered for one year, and the study endpoints were compared between the two groups. Results: The mean age was 62.3±12.1 years and 54.8 % were male. All-cause mortality and readmission occurred in 26.7% and 31.7% of individuals, respectively, without significant differences between the two groups. However, in subgroup analysis, there was a significant relationship between in-hospital mortality and the presence of cardiovascular risk factors. Conclusion: Digoxin might increase in-hospital mortality in patients with underlying cardiovascular risk factors.https://jcvtr.tbzmed.ac.ir/PDF/jcvtr-16-194.pdfheart failuredigoxinmortalityreadmission
spellingShingle Mahsa Behnemoon
Zahra Borumandkia
The effects of digoxin on heart failure mortality and re-admission in a single center cross-sectional study
Journal of Cardiovascular and Thoracic Research
heart failure
digoxin
mortality
readmission
title The effects of digoxin on heart failure mortality and re-admission in a single center cross-sectional study
title_full The effects of digoxin on heart failure mortality and re-admission in a single center cross-sectional study
title_fullStr The effects of digoxin on heart failure mortality and re-admission in a single center cross-sectional study
title_full_unstemmed The effects of digoxin on heart failure mortality and re-admission in a single center cross-sectional study
title_short The effects of digoxin on heart failure mortality and re-admission in a single center cross-sectional study
title_sort effects of digoxin on heart failure mortality and re admission in a single center cross sectional study
topic heart failure
digoxin
mortality
readmission
url https://jcvtr.tbzmed.ac.ir/PDF/jcvtr-16-194.pdf
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