The use of rituximab in the treatment of disimmune polyneuropathy: a description of clinical cases and a literature review
Dysimmune neuropathies are heterogeneous group of acquired immune-mediated diseases, accompanied by damage to the peripheral nervous system. As a standard therapy, prednisolone and intravenous immunoglobulins are used. Also encouraging efficacy is demonstrated by the use of a genetically engineered...
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| Format: | Article |
| Language: | Russian |
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ABV-press
2019-07-01
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| Series: | Нервно-мышечные болезни |
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| Online Access: | https://nmb.abvpress.ru/jour/article/view/327 |
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| _version_ | 1849399736287625216 |
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| author | V. N. Kiselev V. G. Potapenko |
| author_facet | V. N. Kiselev V. G. Potapenko |
| author_sort | V. N. Kiselev |
| collection | DOAJ |
| description | Dysimmune neuropathies are heterogeneous group of acquired immune-mediated diseases, accompanied by damage to the peripheral nervous system. As a standard therapy, prednisolone and intravenous immunoglobulins are used. Also encouraging efficacy is demonstrated by the use of a genetically engineered chimeric monoclonal antibody to the CD20 antigen found on the surface of normal and malignant B-cells – rituximab. Rituximab shows encouraging results. We reviewed the use of rituximab for dysimmune polyneuropathies and described our experience in administration of Lewis–Sumner syndrome and myelin-associated glycoprotein related neuropathy with rituximab. |
| format | Article |
| id | doaj-art-fd14c6c08ea045ceadb4071c9d4a1e94 |
| institution | Kabale University |
| issn | 2222-8721 2413-0443 |
| language | Russian |
| publishDate | 2019-07-01 |
| publisher | ABV-press |
| record_format | Article |
| series | Нервно-мышечные болезни |
| spelling | doaj-art-fd14c6c08ea045ceadb4071c9d4a1e942025-08-20T03:38:15ZrusABV-pressНервно-мышечные болезни2222-87212413-04432019-07-0192505810.17650/2222-8721-2019-9-2-50-58241The use of rituximab in the treatment of disimmune polyneuropathy: a description of clinical cases and a literature reviewV. N. Kiselev0V. G. Potapenko1Russian national Center for Emergency and Radiation Medicine n. a. A. M. NikiforovaCity Clinical Hospital № 31Dysimmune neuropathies are heterogeneous group of acquired immune-mediated diseases, accompanied by damage to the peripheral nervous system. As a standard therapy, prednisolone and intravenous immunoglobulins are used. Also encouraging efficacy is demonstrated by the use of a genetically engineered chimeric monoclonal antibody to the CD20 antigen found on the surface of normal and malignant B-cells – rituximab. Rituximab shows encouraging results. We reviewed the use of rituximab for dysimmune polyneuropathies and described our experience in administration of Lewis–Sumner syndrome and myelin-associated glycoprotein related neuropathy with rituximab.https://nmb.abvpress.ru/jour/article/view/327dysimmune polyneuropathychronic inflammatory demyelinating polyneuropathylewis–sumner syndromeparaproteinmyelin-associated glycoproteinmyelin-associated antibodiesglycoproteinrituximab |
| spellingShingle | V. N. Kiselev V. G. Potapenko The use of rituximab in the treatment of disimmune polyneuropathy: a description of clinical cases and a literature review Нервно-мышечные болезни dysimmune polyneuropathy chronic inflammatory demyelinating polyneuropathy lewis–sumner syndrome paraprotein myelin-associated glycoprotein myelin-associated antibodies glycoprotein rituximab |
| title | The use of rituximab in the treatment of disimmune polyneuropathy: a description of clinical cases and a literature review |
| title_full | The use of rituximab in the treatment of disimmune polyneuropathy: a description of clinical cases and a literature review |
| title_fullStr | The use of rituximab in the treatment of disimmune polyneuropathy: a description of clinical cases and a literature review |
| title_full_unstemmed | The use of rituximab in the treatment of disimmune polyneuropathy: a description of clinical cases and a literature review |
| title_short | The use of rituximab in the treatment of disimmune polyneuropathy: a description of clinical cases and a literature review |
| title_sort | use of rituximab in the treatment of disimmune polyneuropathy a description of clinical cases and a literature review |
| topic | dysimmune polyneuropathy chronic inflammatory demyelinating polyneuropathy lewis–sumner syndrome paraprotein myelin-associated glycoprotein myelin-associated antibodies glycoprotein rituximab |
| url | https://nmb.abvpress.ru/jour/article/view/327 |
| work_keys_str_mv | AT vnkiselev theuseofrituximabinthetreatmentofdisimmunepolyneuropathyadescriptionofclinicalcasesandaliteraturereview AT vgpotapenko theuseofrituximabinthetreatmentofdisimmunepolyneuropathyadescriptionofclinicalcasesandaliteraturereview AT vnkiselev useofrituximabinthetreatmentofdisimmunepolyneuropathyadescriptionofclinicalcasesandaliteraturereview AT vgpotapenko useofrituximabinthetreatmentofdisimmunepolyneuropathyadescriptionofclinicalcasesandaliteraturereview |