UPLC-MS/MS analysis of axitinib and pharmacokinetic application in beagle dogs
Objective: To develop a method for determining the concentration of axitinib in beagle dog plasma and utilize this method to investigate the pharmacokinetics of orally administered axitinib in beagle dogs. Methods: Plasma samples were processed using acetonitrile precipitation and analyzed by UPLC-M...
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Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2024-10-01
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Series: | Heliyon |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844024154539 |
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