Gefitinib-induced skin ulceration in metastatic adenocarcinoma lung
We report a case of gefitinib-induced skin ulceration in a 50-year-old female with metastatic adenocarcinoma of lung who developed this adverse effect 2 weeks following initiation of gefitinib at a dose of 250 mg/day. The ulcer improved with stopping gefitinib for 2 weeks and also addition of topica...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Thieme Medical and Scientific Publishers Pvt. Ltd.
2014-01-01
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| Series: | Indian Journal of Medical and Paediatric Oncology |
| Subjects: | |
| Online Access: | http://www.ijmpo.org/article.asp?issn=0971-5851;year=2014;volume=35;issue=1;spage=109;epage=110;aulast=Sathyanarayanan |
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| _version_ | 1849315875606233088 |
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| author | Vishwanath Sathyanarayanan Kadabur Nagendrappa Lokesh Lakshmaiah Kuntejowdahalli Channaviriappa Linu Abraham Jacob |
| author_facet | Vishwanath Sathyanarayanan Kadabur Nagendrappa Lokesh Lakshmaiah Kuntejowdahalli Channaviriappa Linu Abraham Jacob |
| author_sort | Vishwanath Sathyanarayanan |
| collection | DOAJ |
| description | We report a case of gefitinib-induced skin ulceration in a 50-year-old female with metastatic adenocarcinoma of lung who developed this adverse effect 2 weeks following initiation of gefitinib at a dose of 250 mg/day. The ulcer improved with stopping gefitinib for 2 weeks and also addition of topical steroids and antibiotics. We are reporting this case to create awareness among treating oncologists of this adverse effect and also prompt interruption of therapy and topical steroids/antibiotics is useful to treat this adverse event. |
| format | Article |
| id | doaj-art-fce6b88a203d4b9fb948f2b6f5184f21 |
| institution | Kabale University |
| issn | 0971-5851 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Thieme Medical and Scientific Publishers Pvt. Ltd. |
| record_format | Article |
| series | Indian Journal of Medical and Paediatric Oncology |
| spelling | doaj-art-fce6b88a203d4b9fb948f2b6f5184f212025-08-20T03:52:02ZengThieme Medical and Scientific Publishers Pvt. Ltd.Indian Journal of Medical and Paediatric Oncology0971-58512014-01-0135110911010.4103/0971-5851.133736Gefitinib-induced skin ulceration in metastatic adenocarcinoma lungVishwanath SathyanarayananKadabur Nagendrappa LokeshLakshmaiah Kuntejowdahalli ChannaviriappaLinu Abraham JacobWe report a case of gefitinib-induced skin ulceration in a 50-year-old female with metastatic adenocarcinoma of lung who developed this adverse effect 2 weeks following initiation of gefitinib at a dose of 250 mg/day. The ulcer improved with stopping gefitinib for 2 weeks and also addition of topical steroids and antibiotics. We are reporting this case to create awareness among treating oncologists of this adverse effect and also prompt interruption of therapy and topical steroids/antibiotics is useful to treat this adverse event.http://www.ijmpo.org/article.asp?issn=0971-5851;year=2014;volume=35;issue=1;spage=109;epage=110;aulast=SathyanarayananEpidermal growth factor receptorgefitinibskin ulcerationtyrosine kinase inhibitor |
| spellingShingle | Vishwanath Sathyanarayanan Kadabur Nagendrappa Lokesh Lakshmaiah Kuntejowdahalli Channaviriappa Linu Abraham Jacob Gefitinib-induced skin ulceration in metastatic adenocarcinoma lung Indian Journal of Medical and Paediatric Oncology Epidermal growth factor receptor gefitinib skin ulceration tyrosine kinase inhibitor |
| title | Gefitinib-induced skin ulceration in metastatic adenocarcinoma lung |
| title_full | Gefitinib-induced skin ulceration in metastatic adenocarcinoma lung |
| title_fullStr | Gefitinib-induced skin ulceration in metastatic adenocarcinoma lung |
| title_full_unstemmed | Gefitinib-induced skin ulceration in metastatic adenocarcinoma lung |
| title_short | Gefitinib-induced skin ulceration in metastatic adenocarcinoma lung |
| title_sort | gefitinib induced skin ulceration in metastatic adenocarcinoma lung |
| topic | Epidermal growth factor receptor gefitinib skin ulceration tyrosine kinase inhibitor |
| url | http://www.ijmpo.org/article.asp?issn=0971-5851;year=2014;volume=35;issue=1;spage=109;epage=110;aulast=Sathyanarayanan |
| work_keys_str_mv | AT vishwanathsathyanarayanan gefitinibinducedskinulcerationinmetastaticadenocarcinomalung AT kadaburnagendrappalokesh gefitinibinducedskinulcerationinmetastaticadenocarcinomalung AT lakshmaiahkuntejowdahallichannaviriappa gefitinibinducedskinulcerationinmetastaticadenocarcinomalung AT linuabrahamjacob gefitinibinducedskinulcerationinmetastaticadenocarcinomalung |