Studies on chlorophenyl, thiophenyl, and biphenyl clubbed tetrahydro bipyrazole carbaldehydes: Synthesis, antimicrobial and antioxidant activity, SAR study, in-silico pharmacokinetics, toxicity, and molecular modeling
A library of chlorophenyl, thiophenyl, and biphenyl clubbed 3′,4,4′,5-tetrahydro-2′H-[1,3′-bipyrazole]-2′-carbaldehydes was produced via aldolic condensation followed by hetero-cyclization. Synthesized moieties were characterized by IR, 1H, and 13CNMR spectral analysis. The molecular docking was con...
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| Main Authors: | Avika, Nitin Kumar, Haya Yasin, Shikha Sharma, Suraj N. Mali, Shailesh S. Gurav |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2024-12-01
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| Series: | Chemical Physics Impact |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2667022424002573 |
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