Exploring the therapeutic potential of xanthones in diabetes management: Current insights and future directions

Exploring the therapeutic potential of xanthones in diabetes management: Current insights and future directions

The search for effective antidiabetic agents, both synthetic and natural, has intensified over the years. This review provides a comprehensive examination of xanthone compounds as potential antidiabetic agents, exploring their sources, chemical structures, and pharmacological properties. Xanthones h...

Full description

Saved in:

Bibliographic Details
Main Authors:	Riya Saikia, Kalyani Pathak, Pallab Pramanik, Md Ariful Islam, Shreyasi Karmakar, Saptasikha Gogoi, Manash Pratim Pathak, Dibyajyoti Das, Jon Jyoti Sahariah, Mohammad Zaki Ahmad, Aparoop Das
Format:	Article
Language:	English
Published:	Elsevier 2024-12-01
Series:	European Journal of Medicinal Chemistry Reports
Subjects:	Diabetes mellitus Xanthones SAR Glucose upregulation Diabetic retinopathy Diabetic neuropathy
Online Access:	http://www.sciencedirect.com/science/article/pii/S277241742400061X
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Examining Prenylated Xanthones as Potential Inhibitors Against Ketohexokinase C Isoform for the Treatment of Fructose-Driven Metabolic Disorders: An Integrated Computational Approach
by: Tilal Elsaman, et al.
Published: (2025-01-01)

Nanohybrid cerasomes: Advancements in targeted drug and gene delivery
by: Kalyani Pathak, et al.
Published: (2024-12-01)

ANTIBACTERIAL ACTIVITY OF XANTHONE FROM ETHYL ACETATE EXTRACT OF THE STEAM BARK OF Garcinia picrorrhiza Miq
by: Muharni Muharni, et al.
Published: (2017-08-01)

Exploring green solvent systems and enhanced solubility of xanthone in triglyceride-based tricaprin-tricaprylin mixtures with thermodynamic insights
by: Hua Liu, et al.
Published: (2024-12-01)

α-Mangostin: A Xanthone Derivative in Mangosteen with Potent Anti-Cancer Properties
by: Amin F. Majdalawieh, et al.
Published: (2024-10-01)

Synthesis, In vitro antimicrobial activity, and In silico bioinformatical approach of xanthone-fatty acid esters against Staphylococcus aureus, Escherichia coli, and Candida albicans
by: Yehezkiel Steven Kurniawan, et al.
Published: (2025-04-01)

Clinical Profile and Risk Factors for Complication of Type 2 Diabetes Mellitus at the National Referral Hospital, Bhutan: A Descriptive Cross‐Sectional Study
by: Tshering Norbu, et al.
Published: (2024-11-01)

Diabetic autonomic neuropathy of the gastrointestinal tract
by: Edwin Kuźnik, et al.
Published: (2020-06-01)

Metformin ameliorates peripheral neuropathy in diabetic rats by downregulating autophagy via the AMPK pathway
by: Fangqin You, et al.
Published: (2025-01-01)

APPLICATIONS OF DIABETIC FOOT EXERCISE TO INCREASE FOOT SENSITIVITY IN ELDERLY WITH TYPE 2 DIABETES MELLITUS
by: Siti Aisah, et al.
Published: (2023-10-01)

Foot screening and customized health education program for patients with diabetic peripheral neuropathy: A nurse-led, real-world observational study
by: Shuhong Liu, et al.
Published: (2025-06-01)

Ankle reflex and neurological symptom score: a primary level screening method for diabetic peripheral neuropathy
by: Xueya Ma, et al.
Published: (2024-02-01)

Shared signaling pathways and comprehensive therapeutic approaches among diabetes complications
by: Moein Ebrahimi, et al.
Published: (2025-01-01)

PREDICTION OF DIABETIC RETINOPATHY AMONG DIABETIC NEUROPATHY IN T2DM PATIENTS USING DATA MINING ALGORITHM
by: Nur Balqis Oon, et al.
Published: (2024-10-01)

Regarding Treatment of Painful Diabetic Neuropathy With 10 kHz Spinal Cord Stimulation: Long-Term Improvements in Hemoglobin A1c, Weight, and Sleep Accompany Pain Relief for People With Type 2 Diabetes [Letter]
by: Zhou PB, et al.
Published: (2025-01-01)

Frequency of neuropathy symptoms in diabetic patients
by: Gnanamoorthy Tharani, et al.
Published: (2024-01-01)

Serum Calprotectin Level in Type 2 Diabetic Patients with and without Diabetic Peripheral Neuropathy: A Comparison Study
by: Israa Abdelmalik Salem, et al.
Published: (2024-12-01)

Association of socioeconomic status with diabetic microvascular complications: a UK Biobank prospective cohort study
by: Yikeng Huang, et al.
Published: (2025-01-01)

MULTIDISCIPLINARY APPROACH TO THE DIAGNOSIS AND TREATMENT OF INFECTIOUS COMPLICATIONS OF DIABETIC FOOT SYNDROME
by: Vladimir A. Beloborodov, et al.
Published: (2024-03-01)

Antimalarial activity of caged xanthone isolated compounds from Cratoxylum sumatranum stem bark: In vitro and in silico approaches
by: Firman; Wardana Wicaksana
Published: (2024-10-01)

Vitamin B12 and diabetic neuropathies
by: V.A. Serhiyenko, et al.
Published: (2024-11-01)

Deterioration in ankle reflex is associated with a reduced estimated glomerular filtration rate in patients with type 2 diabetes: A retrospective observational cohort study
by: Taichi Muramatsu, et al.
Published: (2025-02-01)

Expression of microRNA-27b in type 2 diabetic patients and relation to microvascular complications
by: Yehia Mostafa Ghanem, et al.
Published: (2024-12-01)

How do patients and healthcare professionals experience foot examinations in diabetes care? – A randomised controlled study of digital foot examinations versus traditional foot examinations
by: Ulla Hellstrand Tang, et al.
Published: (2024-11-01)

Characteristics of Plantar Pressure Distribution in Diabetes Population with or without Peripheral Neuropathy
by: V. K. Latha, et al.
Published: (2024-11-01)

Application of NerveCheck Master in the Diagnosis of Diabetic Peripheral Neuropathy
by: Raquel García de la Peña, et al.
Published: (2025-01-01)

Association between sensitivity to thyroid hormone indices and type 2 diabetic microvascular complications in euthyroid patients
by: Junping Zhang, et al.
Published: (2024-12-01)

Elevated circulating homocysteine concentrations delayed nerve conduction velocity and increase the risk of diabetic kidney disease in patients with type 2 diabetes
by: Nannan Lv, et al.
Published: (2024-12-01)

Frequency Rhythmic Electrical Modulated System (FREMS) and its effect on the treatment of painful diabetic peripheral neuropathy: A systematic review and meta-analysis.
by: Khaled Moghib, et al.
Published: (2025-01-01)

Metformin Reduces the Risk of Diabetic Neuropathy Among Egyptian Type 2 Diabetic Patients: A Case-Control Study
by: Yomne Hicham, et al.
Published: (2023-12-01)

Development of a clinical prediction model for diabetic peripheral neuropathy with type 2 diabetes mellitus
by: OUYANG Bilu, WANG Guoqiang, WANG Mengmeng, WANG Xiuge
Published: (2024-12-01)

Peripheral Nerve Stimulation for Neuropathic Pain Management: A Narrative Review
by: Zhangyan Mao, et al.
Published: (2024-09-01)

Detecting Presence of Tarsal Tunnel Syndrome in Type II Diabetic Patients using Clinical, Radiological and Electrodiagnostic Studies: A Cross-sectional Study
by: Vipul Kumar, et al.
Published: (2024-11-01)

Impairment of Microcirculation Parameters in Patients with a History of Diabetic Foot Ulcers
by: Julien Vouillarmet, et al.
Published: (2024-12-01)

D1S-Neuro Program: Frequency and Risk Factors for the Development of Diabetic Neuropathy in Pediatric Patients with Type 1 Diabetes Mellitus, a Single Center Study
by: Marco Piccoli, et al.
Published: (2024-12-01)

Efficacy and Safety of Ultrasound-Guided Pulsed Radiofrequency Therapy of Stellate Ganglion on Refractory Painful Diabetic Peripheral Neuropathy
by: Wang J, et al.
Published: (2024-12-01)

Protective role of SIRT1 (rs3758391 T > C) polymorphism against T2DM and its complications: Influence on GPx activity
by: Rozita Naseri, et al.
Published: (2024-11-01)

Assessing the diagnostic utility of urinary albumin-to-creatinine ratio as a potential biomarker for diabetic peripheral neuropathy in type 2 diabetes mellitus patients
by: Hui Zhang, et al.
Published: (2024-11-01)

Association between glycemic control and autonomic dysfunction: A cross-sectional study in type 2 diabetes mellitus patients
by: Jibin Simon, et al.
Published: (2024-06-01)

Cross-cutting effect of type 2 diabetes on the sensorimotor control of balance
by: Trevor Lopatin, et al.
Published: (2025-01-01)