Bioluminescence Imaging of Vascular Endothelial Growth Factor Promoter Activity in Murine Mammary Tumorigenesis

Bioluminescence Imaging of Vascular Endothelial Growth Factor Promoter Activity in Murine Mammary Tumorigenesis

Vascular endothelial growth factor (VEGF) is a major inducer of angiogenesis. We generated a transgenic reporter mouse, VEGF-GL, in which an enhanced green fluorescent protein-luciferase fusion protein is expressed under the control of a human VEGF-A promoter. The VEGF-GL mouse exhibited intense bio...

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Bibliographic Details
Main Authors: Shannon L. Faley, Keiko Takahashi, Cornelia E. Crooke, Joshua T. Beckham, Takuya Tomemori, Scott B. Shappell, E. Duco Jansen, Takamune Takahashi
Format: Article
Language:English
Published: SAGE Publishing 2007-09-01
Series:Molecular Imaging
Online Access:https://doi.org/10.2310/7290.2007.00029
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