The Bio-Uptaking and Fermenting Characteristics of Various Lignocellulose-Digested Mono- and Oligo-Saccharides by <i>Bacillus subtilis</i>

<i>Bacillus subtilis</i> (<i>B. subtilis</i>) has booming application prospects in the feed industry as a value-added probiotic. Considering the intermediate and end saccharides of glucan and xylan digestion during lignocellulose biorefinery processing, the various digested s...

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Main Authors: Liang Wu, Yong Xu
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Fermentation
Subjects:
Online Access:https://www.mdpi.com/2311-5637/11/3/119
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author Liang Wu
Yong Xu
author_facet Liang Wu
Yong Xu
author_sort Liang Wu
collection DOAJ
description <i>Bacillus subtilis</i> (<i>B. subtilis</i>) has booming application prospects in the feed industry as a value-added probiotic. Considering the intermediate and end saccharides of glucan and xylan digestion during lignocellulose biorefinery processing, the various digested saccharides were detected to disclose the bio-uptake and fermenting characteristics by solo or co-fermentation, especially with respect to five monosaccharides, cellobiose, and functional food additive—xylo-oligosaccharides (XOS). <i>B. subtilis</i> can directly ferment XOS without xylose, achieving a cell yield of 0.71 g/g, while it hardly utilizes cellobiose except glucose co-fermentation. With a 5 g/L glucose addition and co-fermentation, bacterial cell yield was improved to 0.70 g/g. In total, <i>B. subtilis</i> had a 0.56–0.90 g/g cell yield from corncob-digested saccharides and the highest saccharide-uptaking rate of 98%. This study provides critical insights and experimental data to advance lignocellulosic biorefinery technologies, particularly for probiotics production and simplification of enzymatic hydrolysis, as well as the potential application in high value-added XOS biopurification.
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series Fermentation
spelling doaj-art-fc42f45f77494f1e9340be63a98ff6a52025-08-20T03:43:30ZengMDPI AGFermentation2311-56372025-03-0111311910.3390/fermentation11030119The Bio-Uptaking and Fermenting Characteristics of Various Lignocellulose-Digested Mono- and Oligo-Saccharides by <i>Bacillus subtilis</i>Liang Wu0Yong Xu1Jiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, College of Chemical Engineering, Nanjing Forestry University, Nanjing 210037, ChinaJiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, College of Chemical Engineering, Nanjing Forestry University, Nanjing 210037, China<i>Bacillus subtilis</i> (<i>B. subtilis</i>) has booming application prospects in the feed industry as a value-added probiotic. Considering the intermediate and end saccharides of glucan and xylan digestion during lignocellulose biorefinery processing, the various digested saccharides were detected to disclose the bio-uptake and fermenting characteristics by solo or co-fermentation, especially with respect to five monosaccharides, cellobiose, and functional food additive—xylo-oligosaccharides (XOS). <i>B. subtilis</i> can directly ferment XOS without xylose, achieving a cell yield of 0.71 g/g, while it hardly utilizes cellobiose except glucose co-fermentation. With a 5 g/L glucose addition and co-fermentation, bacterial cell yield was improved to 0.70 g/g. In total, <i>B. subtilis</i> had a 0.56–0.90 g/g cell yield from corncob-digested saccharides and the highest saccharide-uptaking rate of 98%. This study provides critical insights and experimental data to advance lignocellulosic biorefinery technologies, particularly for probiotics production and simplification of enzymatic hydrolysis, as well as the potential application in high value-added XOS biopurification.https://www.mdpi.com/2311-5637/11/3/119<i>Bacillus subtilis</i>lignocellulose-digested saccharidesxylo-oligosaccharidescellobiosebio-uptaking characteristics
spellingShingle Liang Wu
Yong Xu
The Bio-Uptaking and Fermenting Characteristics of Various Lignocellulose-Digested Mono- and Oligo-Saccharides by <i>Bacillus subtilis</i>
Fermentation
<i>Bacillus subtilis</i>
lignocellulose-digested saccharides
xylo-oligosaccharides
cellobiose
bio-uptaking characteristics
title The Bio-Uptaking and Fermenting Characteristics of Various Lignocellulose-Digested Mono- and Oligo-Saccharides by <i>Bacillus subtilis</i>
title_full The Bio-Uptaking and Fermenting Characteristics of Various Lignocellulose-Digested Mono- and Oligo-Saccharides by <i>Bacillus subtilis</i>
title_fullStr The Bio-Uptaking and Fermenting Characteristics of Various Lignocellulose-Digested Mono- and Oligo-Saccharides by <i>Bacillus subtilis</i>
title_full_unstemmed The Bio-Uptaking and Fermenting Characteristics of Various Lignocellulose-Digested Mono- and Oligo-Saccharides by <i>Bacillus subtilis</i>
title_short The Bio-Uptaking and Fermenting Characteristics of Various Lignocellulose-Digested Mono- and Oligo-Saccharides by <i>Bacillus subtilis</i>
title_sort bio uptaking and fermenting characteristics of various lignocellulose digested mono and oligo saccharides by i bacillus subtilis i
topic <i>Bacillus subtilis</i>
lignocellulose-digested saccharides
xylo-oligosaccharides
cellobiose
bio-uptaking characteristics
url https://www.mdpi.com/2311-5637/11/3/119
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