Hepatocellular carcinoma treated with radical resection after endoscopic diagnosis of the extent of bile duct invasion: A case report
Abstract Hepatocellular carcinoma invasion of the bile duct is rare and has a poor prognosis. A 77‐year‐old man presented at the emergency department with persistent pain in the right hypochondrium. Blood tests and imaging studies revealed a 70‐mm occupying lesion in the right lobe of the liver and...
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| Format: | Article |
| Language: | English |
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Wiley
2024-04-01
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| Series: | DEN Open |
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| Online Access: | https://doi.org/10.1002/deo2.265 |
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| author | Yudai Sato Tomoko Tadokoro Hiroki Yamana Hiraki Akai Kei Takuma Naoki Fujita Mai Nakahara Kyoko Oura Koji Fujita Joji Tani Hideki Kamada Asahiro Morishita Hideki Kobara Seiko Kagawa Reiji Haba Keiichi Okano Tsutomu Masaki |
| author_facet | Yudai Sato Tomoko Tadokoro Hiroki Yamana Hiraki Akai Kei Takuma Naoki Fujita Mai Nakahara Kyoko Oura Koji Fujita Joji Tani Hideki Kamada Asahiro Morishita Hideki Kobara Seiko Kagawa Reiji Haba Keiichi Okano Tsutomu Masaki |
| author_sort | Yudai Sato |
| collection | DOAJ |
| description | Abstract Hepatocellular carcinoma invasion of the bile duct is rare and has a poor prognosis. A 77‐year‐old man presented at the emergency department with persistent pain in the right hypochondrium. Blood tests and imaging studies revealed a 70‐mm occupying lesion in the right lobe of the liver and dilated intrahepatic bile ducts. He was diagnosed with obstructive jaundice and cholangitis. Imaging studies showed an internal mass with poor contrast effects. A liver biopsy was performed to confirm the diagnosis and hepatocellular carcinoma was suspected. Endoscopic retrograde cholangiopancreatography, endoscopic ultrasound, and peroral cholangioscopy were performed to determine the treatment strategy. The bile duct invasion did not extend to the porta hepatis; therefore, right hepatic lobectomy and radical resection were performed. Bile duct invasion in hepatocellular carcinoma is rare and often difficult to diagnose by computed tomography or conventional endoscopic retrograde cholangiopancreatography. However, endoscopic ultrasound and peroral cholangioscopy enable safe and accurate diagnosis of the extent of invasion. |
| format | Article |
| id | doaj-art-fc380b8c52934850ae901bdfcd046599 |
| institution | Kabale University |
| issn | 2692-4609 |
| language | English |
| publishDate | 2024-04-01 |
| publisher | Wiley |
| record_format | Article |
| series | DEN Open |
| spelling | doaj-art-fc380b8c52934850ae901bdfcd0465992025-08-20T03:38:54ZengWileyDEN Open2692-46092024-04-0141n/an/a10.1002/deo2.265Hepatocellular carcinoma treated with radical resection after endoscopic diagnosis of the extent of bile duct invasion: A case reportYudai Sato0Tomoko Tadokoro1Hiroki Yamana2Hiraki Akai3Kei Takuma4Naoki Fujita5Mai Nakahara6Kyoko Oura7Koji Fujita8Joji Tani9Hideki Kamada10Asahiro Morishita11Hideki Kobara12Seiko Kagawa13Reiji Haba14Keiichi Okano15Tsutomu Masaki16Department of Gastroenterology and Neurology Kagawa University KagawaJapanDepartment of Gastroenterology and Neurology Kagawa University KagawaJapanDepartment of Gastroenterology and Neurology Kagawa University KagawaJapanDepartment of Gastroenterology and Neurology Kagawa University KagawaJapanDepartment of Gastroenterology and Neurology Kagawa University KagawaJapanDepartment of Gastroenterology and Neurology Kagawa University KagawaJapanDepartment of Gastroenterology and Neurology Kagawa University KagawaJapanDepartment of Gastroenterology and Neurology Kagawa University KagawaJapanDepartment of Gastroenterology and Neurology Kagawa University KagawaJapanDepartment of Gastroenterology and Neurology Kagawa University KagawaJapanDepartment of Gastroenterology and Neurology Kagawa University KagawaJapanDepartment of Gastroenterology and Neurology Kagawa University KagawaJapanDepartment of Gastroenterology and Neurology Kagawa University KagawaJapanDepartment of Pathology Kagawa University KagawaJapanDepartment of Pathology Kagawa University KagawaJapanDepartment of Gastroenterological Surgery Kagawa University KagawaJapanDepartment of Gastroenterology and Neurology Kagawa University KagawaJapanAbstract Hepatocellular carcinoma invasion of the bile duct is rare and has a poor prognosis. A 77‐year‐old man presented at the emergency department with persistent pain in the right hypochondrium. Blood tests and imaging studies revealed a 70‐mm occupying lesion in the right lobe of the liver and dilated intrahepatic bile ducts. He was diagnosed with obstructive jaundice and cholangitis. Imaging studies showed an internal mass with poor contrast effects. A liver biopsy was performed to confirm the diagnosis and hepatocellular carcinoma was suspected. Endoscopic retrograde cholangiopancreatography, endoscopic ultrasound, and peroral cholangioscopy were performed to determine the treatment strategy. The bile duct invasion did not extend to the porta hepatis; therefore, right hepatic lobectomy and radical resection were performed. Bile duct invasion in hepatocellular carcinoma is rare and often difficult to diagnose by computed tomography or conventional endoscopic retrograde cholangiopancreatography. However, endoscopic ultrasound and peroral cholangioscopy enable safe and accurate diagnosis of the extent of invasion.https://doi.org/10.1002/deo2.265bile duct invasionEUShepatocellular carcinomaperoral cholangioscopysurgery |
| spellingShingle | Yudai Sato Tomoko Tadokoro Hiroki Yamana Hiraki Akai Kei Takuma Naoki Fujita Mai Nakahara Kyoko Oura Koji Fujita Joji Tani Hideki Kamada Asahiro Morishita Hideki Kobara Seiko Kagawa Reiji Haba Keiichi Okano Tsutomu Masaki Hepatocellular carcinoma treated with radical resection after endoscopic diagnosis of the extent of bile duct invasion: A case report DEN Open bile duct invasion EUS hepatocellular carcinoma peroral cholangioscopy surgery |
| title | Hepatocellular carcinoma treated with radical resection after endoscopic diagnosis of the extent of bile duct invasion: A case report |
| title_full | Hepatocellular carcinoma treated with radical resection after endoscopic diagnosis of the extent of bile duct invasion: A case report |
| title_fullStr | Hepatocellular carcinoma treated with radical resection after endoscopic diagnosis of the extent of bile duct invasion: A case report |
| title_full_unstemmed | Hepatocellular carcinoma treated with radical resection after endoscopic diagnosis of the extent of bile duct invasion: A case report |
| title_short | Hepatocellular carcinoma treated with radical resection after endoscopic diagnosis of the extent of bile duct invasion: A case report |
| title_sort | hepatocellular carcinoma treated with radical resection after endoscopic diagnosis of the extent of bile duct invasion a case report |
| topic | bile duct invasion EUS hepatocellular carcinoma peroral cholangioscopy surgery |
| url | https://doi.org/10.1002/deo2.265 |
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