Isoniazid-induced Tenosynovitis: A Rare Case Report
The presentation of pain and numbness in flexor tendons of wrist in a patient on anti-tuberculosis treatment (ATT) with isoniazid should raise a suspicion for possible tenosynovitis. Commonly, tenosynovitis affects the wrist, hand, and fingers, although it can occur in any tendon sheath in the body....
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2024-12-01
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| Series: | Acta Medica International |
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| Online Access: | https://journals.lww.com/10.4103/amit.amit_63_24 |
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| author | Piyush Kumar Jain Pradeep Nirala Mazher Maqusood Ravi Shankar Mishra Abhishek Kumar Pooja Sindwani Ravindra Nath |
| author_facet | Piyush Kumar Jain Pradeep Nirala Mazher Maqusood Ravi Shankar Mishra Abhishek Kumar Pooja Sindwani Ravindra Nath |
| author_sort | Piyush Kumar Jain |
| collection | DOAJ |
| description | The presentation of pain and numbness in flexor tendons of wrist in a patient on anti-tuberculosis treatment (ATT) with isoniazid should raise a suspicion for possible tenosynovitis. Commonly, tenosynovitis affects the wrist, hand, and fingers, although it can occur in any tendon sheath in the body. This is a case report illustrates the occurrence of tenosynovitis in a 60-year-old female subsequent to the initiation of anti-tubercular therapy (ATT) containing isoniazid (INH). The patient presented 2 weeks, without a history of trauma. Clinical examination and diagnostic work-up confirmed tenosynovitis, ruling out other causes of musculoskeletal symptoms. Although rare, INH-induced tenosynovitis should be considered, especially in patients with normal uric acid and rheumatoid arthritis factor levels. Regular monitoring for musculoskeletal side effects during ATT is crucial for timely detection and management. The objective of this case report is to highlight the rare occurrence of INH-induced tenosynovitis and emphasize the importance of its early detection and treatment. |
| format | Article |
| id | doaj-art-fc28dbfbdbd34669a9f7a646550d1b60 |
| institution | Kabale University |
| issn | 2349-0578 2349-0896 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Acta Medica International |
| spelling | doaj-art-fc28dbfbdbd34669a9f7a646550d1b602025-01-06T14:27:38ZengWolters Kluwer Medknow PublicationsActa Medica International2349-05782349-08962024-12-0111326927110.4103/amit.amit_63_24Isoniazid-induced Tenosynovitis: A Rare Case ReportPiyush Kumar JainPradeep NiralaMazher MaqusoodRavi Shankar MishraAbhishek KumarPooja SindwaniRavindra NathThe presentation of pain and numbness in flexor tendons of wrist in a patient on anti-tuberculosis treatment (ATT) with isoniazid should raise a suspicion for possible tenosynovitis. Commonly, tenosynovitis affects the wrist, hand, and fingers, although it can occur in any tendon sheath in the body. This is a case report illustrates the occurrence of tenosynovitis in a 60-year-old female subsequent to the initiation of anti-tubercular therapy (ATT) containing isoniazid (INH). The patient presented 2 weeks, without a history of trauma. Clinical examination and diagnostic work-up confirmed tenosynovitis, ruling out other causes of musculoskeletal symptoms. Although rare, INH-induced tenosynovitis should be considered, especially in patients with normal uric acid and rheumatoid arthritis factor levels. Regular monitoring for musculoskeletal side effects during ATT is crucial for timely detection and management. The objective of this case report is to highlight the rare occurrence of INH-induced tenosynovitis and emphasize the importance of its early detection and treatment.https://journals.lww.com/10.4103/amit.amit_63_24adverse drug reactiontenosynovitistuberculosis |
| spellingShingle | Piyush Kumar Jain Pradeep Nirala Mazher Maqusood Ravi Shankar Mishra Abhishek Kumar Pooja Sindwani Ravindra Nath Isoniazid-induced Tenosynovitis: A Rare Case Report Acta Medica International adverse drug reaction tenosynovitis tuberculosis |
| title | Isoniazid-induced Tenosynovitis: A Rare Case Report |
| title_full | Isoniazid-induced Tenosynovitis: A Rare Case Report |
| title_fullStr | Isoniazid-induced Tenosynovitis: A Rare Case Report |
| title_full_unstemmed | Isoniazid-induced Tenosynovitis: A Rare Case Report |
| title_short | Isoniazid-induced Tenosynovitis: A Rare Case Report |
| title_sort | isoniazid induced tenosynovitis a rare case report |
| topic | adverse drug reaction tenosynovitis tuberculosis |
| url | https://journals.lww.com/10.4103/amit.amit_63_24 |
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