Inhibition of PRC1 elicits immunogenic cell death by triggering ROS-dependent ER stress in colorectal cancer via the Wnt/β-catenin signaling pathway
Abstract Due to the low response rate and severe side effects, the clinical efficacy of current immunotherapy for patients with colorectal cancer (CRC) remains unsatisfactory. Induction of immunogenic cell death (ICD) has been evidenced to be conducive to enhancing the survival benefit of immune che...
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| Main Authors: | Wei Wang, Lijiang Zhou, Xinyu Zhang, Zheng Li |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-08-01
|
| Series: | Biology Direct |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13062-025-00685-0 |
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