Advances in the use of dexmedetomidine during the perioperative period to improve postoperative sleep quality in patients undergoing surgery
There is a high incidence of postoperative sleep and sleep architecture disorders in patients undergoing surgery, and dexmedetomidine (DEX) is commonly used to improve postoperative sleep quality and ameliorate the adverse effects of poor sleep on various organ systems. The continuous intraoperative...
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2024-11-01
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| Series: | Journal of International Medical Research |
| Online Access: | https://doi.org/10.1177/03000605241290715 |
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| _version_ | 1846168874078175232 |
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| author | Chengying Ji Xiaodong Su Chaohui Gao Qijing Liu Ying Liu Qian Fu Boxiong Gao Yatao Liu |
| author_facet | Chengying Ji Xiaodong Su Chaohui Gao Qijing Liu Ying Liu Qian Fu Boxiong Gao Yatao Liu |
| author_sort | Chengying Ji |
| collection | DOAJ |
| description | There is a high incidence of postoperative sleep and sleep architecture disorders in patients undergoing surgery, and dexmedetomidine (DEX) is commonly used to improve postoperative sleep quality and ameliorate the adverse effects of poor sleep on various organ systems. The continuous intraoperative intravenous infusion of DEX, the addition of DEX to postoperative intravenous analgesia pumps, and the continuous infusion of DEX after admission to the intensive care unit are often used clinically to improve postoperative sleep quality at doses of 0.1 to 0.7 μg/kg/hour, but the effects of DEX on sleep quality and structure identified in these studies have been inconsistent. Thus, it is unclear whether DEX improves postoperative sleep quality. The various methods of administering DEX to improve postoperative sleep quality have differing effects, the route used modifies the effect of DEX on sleep structure, and the intrinsic mechanism whereby DEX improves sleep quality remains to be fully investigated. In the present review, we describe new directions for future research into the effects of DEX on postoperative sleep quality and the mechanisms involved, which should help guide the design of further studies. This narrative review was completed according to the Scale for the Assessment of Narrative Review Articles (SANRA). |
| format | Article |
| id | doaj-art-fb940d29b7dd408f8ede00a9a34e6d84 |
| institution | Kabale University |
| issn | 1473-2300 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Journal of International Medical Research |
| spelling | doaj-art-fb940d29b7dd408f8ede00a9a34e6d842024-11-13T11:07:04ZengSAGE PublishingJournal of International Medical Research1473-23002024-11-015210.1177/03000605241290715Advances in the use of dexmedetomidine during the perioperative period to improve postoperative sleep quality in patients undergoing surgeryChengying JiXiaodong SuChaohui GaoQijing LiuYing LiuQian FuBoxiong GaoYatao LiuThere is a high incidence of postoperative sleep and sleep architecture disorders in patients undergoing surgery, and dexmedetomidine (DEX) is commonly used to improve postoperative sleep quality and ameliorate the adverse effects of poor sleep on various organ systems. The continuous intraoperative intravenous infusion of DEX, the addition of DEX to postoperative intravenous analgesia pumps, and the continuous infusion of DEX after admission to the intensive care unit are often used clinically to improve postoperative sleep quality at doses of 0.1 to 0.7 μg/kg/hour, but the effects of DEX on sleep quality and structure identified in these studies have been inconsistent. Thus, it is unclear whether DEX improves postoperative sleep quality. The various methods of administering DEX to improve postoperative sleep quality have differing effects, the route used modifies the effect of DEX on sleep structure, and the intrinsic mechanism whereby DEX improves sleep quality remains to be fully investigated. In the present review, we describe new directions for future research into the effects of DEX on postoperative sleep quality and the mechanisms involved, which should help guide the design of further studies. This narrative review was completed according to the Scale for the Assessment of Narrative Review Articles (SANRA).https://doi.org/10.1177/03000605241290715 |
| spellingShingle | Chengying Ji Xiaodong Su Chaohui Gao Qijing Liu Ying Liu Qian Fu Boxiong Gao Yatao Liu Advances in the use of dexmedetomidine during the perioperative period to improve postoperative sleep quality in patients undergoing surgery Journal of International Medical Research |
| title | Advances in the use of dexmedetomidine during the perioperative period to improve postoperative sleep quality in patients undergoing surgery |
| title_full | Advances in the use of dexmedetomidine during the perioperative period to improve postoperative sleep quality in patients undergoing surgery |
| title_fullStr | Advances in the use of dexmedetomidine during the perioperative period to improve postoperative sleep quality in patients undergoing surgery |
| title_full_unstemmed | Advances in the use of dexmedetomidine during the perioperative period to improve postoperative sleep quality in patients undergoing surgery |
| title_short | Advances in the use of dexmedetomidine during the perioperative period to improve postoperative sleep quality in patients undergoing surgery |
| title_sort | advances in the use of dexmedetomidine during the perioperative period to improve postoperative sleep quality in patients undergoing surgery |
| url | https://doi.org/10.1177/03000605241290715 |
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