Effects of innovative modular prone positioning tools in patients with acute respiratory distress syndrome due to COVID-19 during awake prone position: a prospective randomized controlled trial
Abstract Objectives Our aim is to investigate the effects of a innovative modular prone positioning tools on patients with acute respiratory distress syndrome (ARDS) caused by COVID-19 during awake prone positioning (AW-PP). Methods This prospective randomized controlled study initially enrolled 168...
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BMC
2024-12-01
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| Series: | European Journal of Medical Research |
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| Online Access: | https://doi.org/10.1186/s40001-024-02252-1 |
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| author | Dunbing Huang Huan Tian Wei Song Jiaqi Wang Zizhe Yao Lize Xiong Cai Jiang Anren Zhang Xiaohua Ke |
| author_facet | Dunbing Huang Huan Tian Wei Song Jiaqi Wang Zizhe Yao Lize Xiong Cai Jiang Anren Zhang Xiaohua Ke |
| author_sort | Dunbing Huang |
| collection | DOAJ |
| description | Abstract Objectives Our aim is to investigate the effects of a innovative modular prone positioning tools on patients with acute respiratory distress syndrome (ARDS) caused by COVID-19 during awake prone positioning (AW-PP). Methods This prospective randomized controlled study initially enrolled 168 patients with COVID-19 due to ARDS. However, 92 were subsequently disqualified, leaving 76 patients who were randomly assigned to either the observation group (n = 38) or the control group (n = 38). The observation group utilized innovative modular prone positioning tools for non-invasive respiratory support (NIRS), while the control group used soft pillows for the same treatment. Data were collected on comfort levels, adverse events, and efficacy indicators. Additionally, the comfort, incidence of adverse events, and treatment efficacy in both groups were evaluated. Results The observation group had shorter the daily duration spent on executing the AW-PP (2.74 ± 0.86 min vs. 4.64 ± 1.02 min, P < 0.001), longer the daily total AW-PP (8.52 ± 1.01 h vs. 6.03 ± 0.66 h, P < 0.001), longer the daily duration until the first position adjustment (59.89 ± 12.73 min vs. 36.57 ± 8.69 min, P < 0.001), and lower the daily frequency of position adjustments during the AW-PP (11.03 ± 2.67 vs. 17.95 ± 2.58, P < 0.001) in comparison with the control group. No significant differences were observed in intubation rates, mortality, the daily number of hours under HFNO and NIV, escalated to NIV from HFNO, and hospital length of stay between the groups (P > 0.05). However, the observation group experienced significantly fewer adverse events, including kinking NIRS circuit, pain, shortness of breath, dizziness, and pressure ulcers (P < 0.05). Conclusion Innovative modular prone positioning tools improved efficiency, comfort, and reduced adverse events during AW-PP but did not affect intubation rates or mortality. |
| format | Article |
| id | doaj-art-fb7948da2c1f415caae9c5a4b61d9e05 |
| institution | Kabale University |
| issn | 2047-783X |
| language | English |
| publishDate | 2024-12-01 |
| publisher | BMC |
| record_format | Article |
| series | European Journal of Medical Research |
| spelling | doaj-art-fb7948da2c1f415caae9c5a4b61d9e052025-01-05T12:12:17ZengBMCEuropean Journal of Medical Research2047-783X2024-12-0129111110.1186/s40001-024-02252-1Effects of innovative modular prone positioning tools in patients with acute respiratory distress syndrome due to COVID-19 during awake prone position: a prospective randomized controlled trialDunbing Huang0Huan Tian1Wei Song2Jiaqi Wang3Zizhe Yao4Lize Xiong5Cai Jiang6Anren Zhang7Xiaohua Ke8Department of Rehabilitation Medicine, Shanghai Fourth People’s Hospital, School of Medicine, Tongji UniversityDepartment of Rehabilitation Medicine, Shanghai Fourth People’s Hospital, School of Medicine, Tongji UniversityDepartment of Rehabilitation Medicine, Shanghai Fourth People’s Hospital, School of Medicine, Tongji UniversityDepartment of Rehabilitation Medicine, Shanghai Fourth People’s Hospital, School of Medicine, Tongji UniversityDepartment of Rehabilitation Medicine, Shanghai Fourth People’s Hospital, School of Medicine, Tongji UniversityShanghai Key Laboratory of Anesthesiology and Brain Functional Modulation, Translational Research Institute of Brain and Brain-Like Intelligence, School of Medicine, Shanghai Fourth People’s Hospital, Tongji UniversityShengli Clinical Medical College of Fujian Medical UniversityDepartment of Rehabilitation Medicine, Shanghai Fourth People’s Hospital, School of Medicine, Tongji UniversityDepartment of Rehabilitation Medicine, Shanghai Fourth People’s Hospital, School of Medicine, Tongji UniversityAbstract Objectives Our aim is to investigate the effects of a innovative modular prone positioning tools on patients with acute respiratory distress syndrome (ARDS) caused by COVID-19 during awake prone positioning (AW-PP). Methods This prospective randomized controlled study initially enrolled 168 patients with COVID-19 due to ARDS. However, 92 were subsequently disqualified, leaving 76 patients who were randomly assigned to either the observation group (n = 38) or the control group (n = 38). The observation group utilized innovative modular prone positioning tools for non-invasive respiratory support (NIRS), while the control group used soft pillows for the same treatment. Data were collected on comfort levels, adverse events, and efficacy indicators. Additionally, the comfort, incidence of adverse events, and treatment efficacy in both groups were evaluated. Results The observation group had shorter the daily duration spent on executing the AW-PP (2.74 ± 0.86 min vs. 4.64 ± 1.02 min, P < 0.001), longer the daily total AW-PP (8.52 ± 1.01 h vs. 6.03 ± 0.66 h, P < 0.001), longer the daily duration until the first position adjustment (59.89 ± 12.73 min vs. 36.57 ± 8.69 min, P < 0.001), and lower the daily frequency of position adjustments during the AW-PP (11.03 ± 2.67 vs. 17.95 ± 2.58, P < 0.001) in comparison with the control group. No significant differences were observed in intubation rates, mortality, the daily number of hours under HFNO and NIV, escalated to NIV from HFNO, and hospital length of stay between the groups (P > 0.05). However, the observation group experienced significantly fewer adverse events, including kinking NIRS circuit, pain, shortness of breath, dizziness, and pressure ulcers (P < 0.05). Conclusion Innovative modular prone positioning tools improved efficiency, comfort, and reduced adverse events during AW-PP but did not affect intubation rates or mortality.https://doi.org/10.1186/s40001-024-02252-1Innovative modular prone positioning toolsAwake prone positionAcute respiratory distress syndromeCOVID-19Randomized controlled trial |
| spellingShingle | Dunbing Huang Huan Tian Wei Song Jiaqi Wang Zizhe Yao Lize Xiong Cai Jiang Anren Zhang Xiaohua Ke Effects of innovative modular prone positioning tools in patients with acute respiratory distress syndrome due to COVID-19 during awake prone position: a prospective randomized controlled trial European Journal of Medical Research Innovative modular prone positioning tools Awake prone position Acute respiratory distress syndrome COVID-19 Randomized controlled trial |
| title | Effects of innovative modular prone positioning tools in patients with acute respiratory distress syndrome due to COVID-19 during awake prone position: a prospective randomized controlled trial |
| title_full | Effects of innovative modular prone positioning tools in patients with acute respiratory distress syndrome due to COVID-19 during awake prone position: a prospective randomized controlled trial |
| title_fullStr | Effects of innovative modular prone positioning tools in patients with acute respiratory distress syndrome due to COVID-19 during awake prone position: a prospective randomized controlled trial |
| title_full_unstemmed | Effects of innovative modular prone positioning tools in patients with acute respiratory distress syndrome due to COVID-19 during awake prone position: a prospective randomized controlled trial |
| title_short | Effects of innovative modular prone positioning tools in patients with acute respiratory distress syndrome due to COVID-19 during awake prone position: a prospective randomized controlled trial |
| title_sort | effects of innovative modular prone positioning tools in patients with acute respiratory distress syndrome due to covid 19 during awake prone position a prospective randomized controlled trial |
| topic | Innovative modular prone positioning tools Awake prone position Acute respiratory distress syndrome COVID-19 Randomized controlled trial |
| url | https://doi.org/10.1186/s40001-024-02252-1 |
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