Anti-inflammatory potential of black cumin seed oil and its nanoemulsion formulation against lipopolysaccharide-induced liver injury in mice

Anti-inflammatory potential of black cumin seed oil and its nanoemulsion formulation against lipopolysaccharide-induced liver injury in mice

Objective: To evaluate the anti-inflammatory effect of black cumin seed oil (BCSO) and its nanoemulsion on lipopolysaccharide (LPS)-induced liver injury in mice. Methods: LPS-induced acute liver injury mouse model was used to evaluate the effects of BCSO and its nanoemulsion formulation on liver fun...

Full description

Saved in:

Bibliographic Details
Main Authors:	Hesham Haffez, Rehab Hosni, Shady A. Swidan, Hatem K. Amin
Format:	Article
Language:	English
Published:	Wolters Kluwer Medknow Publications 2024-12-01
Series:	Asian Pacific Journal of Tropical Biomedicine
Subjects:	black cumin seed oil liver inflammation lipopolysaccharide oxidative stress il-6 tlr4 apoptosis
Online Access:	https://journals.lww.com/10.4103/apjtb.apjtb_448_24
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Evaluating the Thymoquinone Content and Antioxidant Properties of Black Cumin (<i>Nigella sativa</i> L.) Seed Oil During Storage at Different Thermal Treatments
by: Grażyna Neunert, et al.
Published: (2025-01-01)

Effects of Different Organic Fertilizers on Yield and Yield-Related Characteristics in Black Cumin (Nigella sativa L.) Cultivation Under the Ecological Conditions of Tokat, Türkiye
by: Abdulkadir Acar, et al.
Published: (2025-01-01)

Efficacy of Black Cumin (Nigella sativa) Ameliorate Organophosphate Toxicity in Pregnant Rats Based on Progesterone Levels and Fetal Bone Development
by: Viski Fitri Hendrawan, et al.
Published: (2024-04-01)

Effect of Black Cumin on the Expression of Genes Related to Lipid Metabolism in Adipose Tissue: A Mouse Model Study
by: Roya Maleki, et al.
Published: (2024-02-01)

The Effect of Cumin on the Formation of <i>β</i>-Carboline Heterocyclic Amines in Smoked Meat and Simulated Systems
by: Xiuxiu Liu, et al.
Published: (2025-01-01)

The effect of water, urea, sodium hydroxide, and hydrogen peroxide processing on the cumin residues animal digestibility
by: Farkhondeh Rezaii, et al.
Published: (2023-12-01)

Optimizing plant density to improve the soil microenvironment and enhance crop productivity in cotton/cumin intercropping systems
by: Humei Zhang, et al.
Published: (2025-02-01)

Comparison of the Effect of New Spice Freon Extracts Towards Ground Spices and Antioxidants for Improving the Quality of Bulgarian-Type Dry-Cured Sausage
by: Balev Dessislav Kostadinov, et al.
Published: (2017-03-01)

Protective Effects of Chitosan Oligosaccharide Against Lipopolysaccharide-Induced Inflammatory Response and Oxidative Stress in Bovine Mammary Epithelial Cells
by: Ziwei Lin, et al.
Published: (2025-01-01)

PENGARUH PEMAKAIAN KOMBINASI MINYAK JINTEN HITAM (Nigella sativa) dan MADU (Apis mellifera) SEBAGAI ANTI-ACNE SECARA TOPIKAL PADA SUKARELAWAN WANITA
by: Baiq Lenysia Puspita Anjani, et al.
Published: (2015-11-01)

Lipopolysaccharide alters CEBPβ signaling and reduces estradiol production in bovine granulosa cells
by: Mackenzie J. Dickson, et al.
Published: (2022-10-01)

Protective Effect of Black Bean-Whey Double Protein Diet on Intestinal Barrier Injury Induced by Lipopolysaccharide in Rats
by: Weihong MENG, et al.
Published: (2025-01-01)

Toll-like receptor 2-mediated ERK activation significantly upregulates interleukin-6 expression in M2-polarized macrophages
by: Jo Wol Soon, et al.
Published: (2024-10-01)

Effect of dual targeting procyanidins nanoparticles on metabolomics of lipopolysaccharide-stimulated inflammatory macrophages
by: Shanshan Tie, et al.
Published: (2023-11-01)

Cisplatin and lipopolysaccharide co-administration for renal injury model in mice
by: Sae-Byeok Hwang, et al.
Published: (2024-12-01)

Effects of heat stress abatement on behavioral response in lactating dairy cows prior to and following an intramammary lipopolysaccharide infusion
by: T.N. Marins, et al.
Published: (2025-02-01)

Antioxidant and Anti-Inflammatory Potential of Cymbopogon nardus Ethanol Extract on 3T3-L1 Cells
by: Rohmawaty E, et al.
Published: (2025-02-01)

Influence of organism stimulation with bacterial lipopolysaccharide on nitric oxide production and metabolism in rat heart on the background of metabolic syndrome
by: O. Ye. Akimov, et al.
Published: (2023-12-01)

Catalpol alleviates the lipopolysaccharide-induced inflammatory response of BV2 cells
by: Sijie Liu, et al.
Published: (2024-12-01)

Reinvestigation into the role of lipopolysaccharide Glycosyltransferases in Helicobacter pylori protein glycosylation
by: Hong Li, et al.
Published: (2025-12-01)

Biosynthetic pathway for leukotrienes is stimulated by lipopolysaccharide and cytokines in pig endometrial stromal cells
by: Barbara Jana, et al.
Published: (2025-01-01)

Effects of macrolide antibiotics on blood inflammatory mediators and organ damage markers in lipopolysaccharide-induced pulmonary damage rats
by: Ayşe Er, et al.

Influence of organism stimulation with bacterial lipopolysaccharide on the metabolism of the extracellular matrix of the heart of rats under conditions of experimental metabolic syndrome
by: O.Ye. Akimov, et al.
Published: (2024-04-01)

Isolation and optimization of Bacillus thuringiensis BRB-3 isolated from germinated black upland rice seeds for GABA production
by: Rungnapha Wannasutta, et al.
Published: (2025-02-01)

The Effect of Lipopolysaccharides from <i>Salmonella enterica</i> on the Size, Density, and Compressibility of Phospholipid Vesicles
by: Tamás Szabó, et al.
Published: (2025-01-01)

Optimization of nanoemulsion hair serum from chia seed oil using the Simplex Lattice Design method
by: Mayu Rahmayanti, et al.
Published: (2024-11-01)

Effects of lipopolysaccharide infusion on feed intake, apparent digestibility, rumen fermentation and microorganisms of young Holstein bulls fed diets with different ratios of lysine and methionine
by: Huiyao Wang, et al.
Published: (2025-01-01)

Mechanistic insights into 125I seed implantation therapy for Cholangiocarcinoma: focus on ROS-Mediated apoptosis and the role of GPX2
by: Jun Luo, et al.
Published: (2024-06-01)

Interrelationships of the Intestinal Microbiome, Trimethylamine N-Oxide and Lipopolysaccharide-Binding Protein with Crohn’s Disease Activity
by: Yelena Laryushina, et al.
Published: (2024-12-01)

IRF3 Promotes Production of IL-6 and Nitric Oxide but Represses CCL22 in RAW264.7 Macrophage Cells Exposed to Lipopolysaccharides in Culture
by: Moore TC, et al.
Published: (2025-01-01)

Exploring the Impact of Drought Stress on the Yield and Yield Components of Cumin (Cuminum cyminum L.) Ecotypes
by: Vahid Bazr Afshan, et al.
Published: (2025-09-01)

The regenerating gene (Reg) family genes in inflammatory bowel disease (IBD)
by: Shin Takasawa, et al.
Published: (2025-02-01)

Lipopolysaccharide inhibits osteoblast formation and receptor activator of nuclear factor-κB ligand degradation via autophagy inhibition
by: Huaizhi Zhang, et al.
Published: (2024-04-01)

Cuminum Cyminum L Encapsulation on Perlite/calcium alginate/single walled carbon nanotubes -Glucose Composite: Fabrication, Characterization, Antibacterial and Antifungal Properties
by: Mahdieh Chegeni, et al.
Published: (2023-07-01)

Microbial diversity and food safety in duck meat preservation: effects of nanoemulsion nutmeg seed extract with focus on proteobacteria and lactococcus
by: Supamri Supamri, et al.
Published: (2025-12-01)

Effect of ozonation on the phytochemicals of black seed oil and its anti-microbial, anti-oxidant, anti-inflammatory, and anti-neoplastic activities in vitro
by: Aisha M. H. Al-Rajhi, et al.
Published: (2024-12-01)

Seed banking impacts native Acacia ulicifolia seed microbiome composition and function
by: Dylan Russell, et al.
Published: (2025-01-01)

In vitro and molecular docking evaluation of black sesame seeds' anti-prostate cancer and antioxidant activity processed by nine steaming nine drying
by: Glennielyn D. Magdamit, et al.
Published: (2025-01-01)

Physiological and sanitary quality of soybean seeds in response to harvest delay
by: Carlos Henrique Conceição Sousa, et al.
Published: (2025-01-01)

Editorial: Regulation of ovule and seed development
by: Prakash Babu Adhikari, et al.
Published: (2025-01-01)